Toxin-Based Targeted Therapy for Malignant Brain Tumors by Vidyalakshmi Chandramohan, John H. Sampson, Ira Pastan, Darell D. Bigner

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Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells. by Matthew Wortham, Genglin Jin, Julia Lailai Sun, Darell D Bigner, Yiping He, Hai Yan

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Monitoring Radiographic Brain Tumor Progression by John H. Sampson, Darell D. Bigner, Allan H. Friedman, Charles W. Kanaly, Ankit I. Mehta

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Development of a high-throughput screening platform to identify new therapeutic agents for Medulloblastoma Group 3 by Inés Fallon, Henar Hernando, Olga Almacellas-Rabaiget, Berta Marti-Fuster, Cesare Spadoni, Darell D Bigner, Eva Méndez

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Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors. by Xin Yu, Mikhail Dobrikov, Stephen T Keir, Matthias Gromeier, Ira H Pastan, Ralph Reisfeld, Darell D Bigner, Vidyalakshmi Chandramohan

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Immunotoxin Therapy for Lung Cancer by Li-Yi Xie, Hai-Lan Piao, Min Fan, Zhen Zhang, Chen Wang, Darell D Bigner, Xu-Hui Bao

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Imaging of Convection Enhanced Delivery of Toxins in Humans by Allan H. Friedman, Darell D. Bigner, John H. Sampson, Ira Pastan, Martin Brady, Raghu Raghavan, Bryan D. Choi, Ankit I. Mehta

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Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity by Mubeen M. Mosaheb, Elena Y. Dobrikova, Michael C. Brown, Yuanfan Yang, Jana Cable, Hideho Okada, Smita K. Nair, Darell D. Bigner, David M. Ashley, Matthias Gromeier

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A novel method for volumetric MRI response assessment of enhancing brain tumors. by Charles W Kanaly, Dale Ding, Ankit I Mehta, Anthony F Waller, Ian Crocker, Annick Desjardins, David A Reardon, Allan H Friedman, Darell D Bigner, John H Sampson

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Intratumor childhood vaccine-specific CD4+ T-cell recall coordinates antitumor CD8+ T cells and eosinophils by Daniel Landi, Annick Desjardins, Matthias Gromeier, Darell D Bigner, Smita K Nair, Michael C Brown, Georgia M Beasley, David M Ashley, Yuanfan Yang, Zachary P McKay, Dina M Randazzo

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Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma by Matthias Gromeier, Darell D Bigner, Smita K Nair, Karenia Landa, Sin-Ho Jung, Georgia M Beasley, Norma E Farrow, Maria Angelica Selim, Carol Ann Wiggs, Andrea True Kelly, April KS Salama

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Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations by Vidyalakshmi Chandramohan, Xuhui Bao, Xin Yu, Scott Parker, Charlotte McDowall, Yen-Rei Yu, Patrick Healy, Annick Desjardins, Michael D. Gunn, Matthias Gromeier, Smita K. Nair, Ira H. Pastan, Darell D. Bigner

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Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice. by Luis A Sanchez-Perez, Bryan D Choi, Gary E Archer, Xiuyu Cui, Catherine Flores, Laura A Johnson, Robert J Schmittling, David Snyder, James E Herndon, Darell D Bigner, Duane A Mitchell, John H Sampson

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Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling by Michael C. Brown, Mubeen M. Mosaheb, Malte Mohme, Zachary P. McKay, Eda K. Holl, Jonathan P. Kastan, Yuanfan Yang, Georgia M. Beasley, E. Shelley Hwang, David M. Ashley, Darell D. Bigner, Smita K. Nair, Matthias Gromeier

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Application of mutagen sensitivity assay in a glioma case-control study by Serap Erdal, Bridget J. McCarthy, Natalia Gurule, Marianne Berwick, Emily Gonzales, Johanna Byrd, Kristina Flores, JoAnna Shimek, Dora Il’yasova, Francis Ali-Osman, Darell D. Bigner, Faith G. Davis, Alexis N. Leyba, Kirsten A.M. White

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Multimodality analysis confers a prognostic benefit of a T-cell infiltrated tumor microenvironment and peripheral immune status in patients with melanoma by Matthias Gromeier, Darell D Bigner, Smita K Nair, David Boczkowski, Michael C Brown, Karenia Landa, Sin-Ho Jung, Georgia M Beasley, Norma E Farrow, Maria Angelica Selim, Rami N Al-Rohil, Aaron D Therien, Junheng Gao, Eda K Holl

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EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma. by Hongsheng Miao, Bryan D Choi, Carter M Suryadevara, Luis Sanchez-Perez, Shicheng Yang, Gabriel De Leon, Elias J Sayour, Roger McLendon, James E Herndon, Patrick Healy, Gary E Archer, Darell D Bigner, Laura A Johnson, John H Sampson

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Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells. by Laura M Epple, Rebecca D Dodd, Andrea L Merz, Anjelika M Dechkovskaia, Matthew Herring, Benjamin A Winston, Alex M Lencioni, Rae L Russell, Helen Madsen, Meheret Nega, Nathaniel L Dusto, Jason White, Darell D Bigner, Christopher V Nicchitta, Natalie J Serkova, Michael W Graner

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A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma. by John H Sampson, Robert J Schmittling, Gary E Archer, Kendra L Congdon, Smita K Nair, Elizabeth A Reap, Annick Desjardins, Allan H Friedman, Henry S Friedman, James E Herndon, April Coan, Roger E McLendon, David A Reardon, James J Vredenburgh, Darell D Bigner, Duane A Mitchell

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The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma by Bill H. Diplas, Xujun He, Jacqueline A. Brosnan-Cashman, Heng Liu, Lee H. Chen, Zhaohui Wang, Casey J. Moure, Patrick J. Killela, Daniel B. Loriaux, Eric S. Lipp, Paula K. Greer, Rui Yang, Anthony J. Rizzo, Fausto J. Rodriguez, Allan H. Friedman, Henry S. Friedman, Sizhen Wang, Yiping He, Roger E. McLendon, Darell D. Bigner, Yuchen Jiao, Matthew S. Waitkus, Alan K. Meeker, Hai Yan

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