Evaluation of a French adaptation of a community-based advance serious illness planning decision aid by Ariane Plaisance, Jennifer Mallmes, Anna Kamateros, Daren K. Heyland

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Coagulase-Negative Staphylococcus, Catheter-Related, Bloodstream Infections and their Association with Acute Phase Markers of Inflammation in the Intensive Care Unit: An Observatio... by Oleksa Rewa, John Muscedere, Steve Reynolds, Xuran Jiang, Daren K Heyland

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Exploring patient-reported barriers to advance care planning in family practice by Carrie Bernard, Amy Tan, Marissa Slaven, Dawn Elston, Daren K. Heyland, Michelle Howard

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Toward Optimal End-of-Life Care for Patients with Advanced Chronic Obstructive Pulmonary Disease: Insights from a Multicentre Study by Graeme M Rocker, Peter M Dodek, Daren K Heyland, for the Canadian Researchers at the End of Life Network

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Decision support intervention (Plan Well Guide) for patients and their substitute decision-makers to improve engagement in advance care planning: protocol for a randomised trial by Michelle Howard, Daren K Heyland, Amy Tan, Carrie Bernard, Marissa Slaven, Sayem Borhan, Dawn Elston, Neha Arora

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Impact of Candida Species on Clinical Outcomes in Patients with Suspected Ventilator-Associated Pneumonia by Marie-Soleil Delisle, David R Williamson, Martin Albert, Marc M Perreault, Xuran Jiang, Andrew G Day, Daren K Heyland

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Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation... by Daren K Heyland, Andrew Day, G John Clarke, Catherine (Terri) Hough, D Clark Files, Marina Mourtzakis, Nicolaas Deutz, Dale M Needham, Renee Stapleton

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Intravenous vitamin C monotherapy in critically ill patients: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis by Zheng-Yii Lee, Luis Ortiz-Reyes, Charles Chin Han Lew, M. Shahnaz Hasan, Lu Ke, Jayshil J. Patel, Christian Stoppe, Daren K. Heyland

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Early versus delayed enteral nutrition in mechanically ventilated patients with circulatory shock: a nested cohort analysis of an international multicenter, pragmatic clinical tria... by Luis Ortiz-Reyes, Jayshil J. Patel, Xuran Jiang, Angel Coz Yataco, Andrew G. Day, Faraaz Shah, James Zelten, Maximiliano Tamae-Kakazu, Todd Rice, Daren K. Heyland

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Frailty as a sequela of burn injury: a post hoc analysis of the “RE-ENERGIZE” multicenter randomized-controlled trial and the National Health Interview Survey by Adriana C. Panayi, Daren K. Heyland, Christian Stoppe, Marc G. Jeschke, Samuel Knoedler, Christian Tapking, Oliver Didzun, Valentin Haug, Amir K. Bigdeli, Ulrich Kneser, Dennis P. Orgill, Gabriel Hundeshagen

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Preoperative Nutritional Optimization and Physical Exercise for Patients Scheduled for Elective Implantation for a Left-Ventricular Assist Device—The PROPER-LVAD Study by Aileen Hill, Vera von Dossow, Daren K. Heyland, Rolf Rossaint, Patrick Meybohm, Henrik Fox, Michiel Morshuis, Gunnar Elke, Bernd Panholzer, Assad Haneya, Andreas Böning, Bernd Niemann, Rashad Zayat, Ajay Moza, Christian Stoppe

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Family-Reported Experiences Evaluation (FREE) study: a mixed-methods study to evaluate families’ satisfaction with adult critical care services in the NHS by Stephen E Wright, Emma Walmsley, Sheila E Harvey, Emily Robinson, Paloma Ferrando-Vivas, David A Harrison, Ruth R Canter, Elaine McColl, Annette Richardson, Michael Richardson, Lisa Hinton, Daren K Heyland, Kathryn M Rowan

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Family satisfaction with critical care in the UK: a multicentre cohort study by Lisa Hinton, Michael Richardson, Ruth Canter, Kathryn M Rowan, Daren K Heyland, David A Harrison, Paloma Ferrando, Doug W Gould, Emma Walmsley, Alvin Richards-Belle, Steven Saunders, Sheila Harvey, Annette Richardson, Stephen E Wright

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A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial by Paul E. Wischmeyer, Michel Hasselmann, Christine Kummerlen, Rosemary Kozar, Demetrios James Kutsogiannis, Constantine J. Karvellas, Beth Besecker, David K. Evans, Jean-Charles Preiser, Leah Gramlich, Khursheed Jeejeebhoy, Rupinder Dhaliwal, Xuran Jiang, Andrew G. Day, Daren K. Heyland

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Identifying a target group for selenium supplementation in high-risk cardiac surgery: a secondary analysis of the SUSTAIN CSX trial by Quirin Notz, Daren K. Heyland, Zheng-Yii Lee, Johannes Menger, Johannes Herrmann, Thilo S. Chillon, Stephen Fremes, Siamak Mohammadi, Gunnar Elke, C. David Mazer, Aileen Hill, Markus Velten, Sascha Ott, Maren Kleine-Brueggeney, Patrick Meybohm, Lutz Schomburg, Christian Stoppe

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The Clinical Frailty Scale for mortality prediction of old acutely admitted intensive care patients: a meta-analysis of individual patient-level data by Raphael Romano Bruno, Bernhard Wernly, Sean M. Bagshaw, Mark van den Boogaard, Jai N. Darvall, Lina De Geer, Pablo Ruiz de Gopegui Miguelena, Daren K. Heyland, David Hewitt, Aluko A. Hope, Emilie Langlais, Pascale Le Maguet, Carmel L. Montgomery, Dimitrios Papageorgiou, Philippe Seguin, Wytske W. Geense, J. Alberto Silva-Obregón, Georg Wolff, Amin Polzin, Lisa Dannenberg, Malte Kelm, Hans Flaatten, Michael Beil, Marcus Franz, Sigal Sviri, Susannah Leaver, Bertrand Guidet, Ariane Boumendil, Christian Jung

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Lessening Organ Dysfunction With Vitamin C (LOVIT) Trial: Statistical Analysis Plan by Neill KJ Adhikari, Ruxandra Pinto, Andrew G Day, Marie-Hélène Masse, Julie Ménard, Sheila Sprague, Djillali Annane, Yaseen M Arabi, Marie-Claude Battista, Dian Cohen, Deborah J Cook, Gordon H Guyatt, Daren K Heyland, Salmaan Kanji, Shay P McGuinness, Rachael L Parke, Bharath Kumar Tirupakuzhi Vijayaraghavan, Emmanuel Charbonney, Michaël Chassé, Lorenzo Del Sorbo, Demetrios James Kutsogiannis, François Lauzier, Rémi Leblanc, David M Maslove, Sangeeta Mehta, Armand Mekontso Dessap, Tina S Mele, Bram Rochwerg, Oleksa G Rewa, Jason Shahin, Pawel Twardowski, Paul Jeffrey Young, François Lamontagne

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