Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity by Yuan Zhang, Na Li, Heikyung Suh, Darrell J. Irvine

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Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade by Ganapathy Sriram, Tiffany R. Emmons, Lauren E. Milling, Darrell J. Irvine, Michael B. Yaffe

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Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer by Dobrin Draganov, Zhen Han, Aamir Rana, Nitasha Bennett, Darrell J. Irvine, Peter P. Lee

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DNA-Loaded Cationic Liposomes Efficiently Function as a Vaccine against Malarial Proteins by Wesley L. Fotoran, Rachele Santangelo, Beatriz N.M. de Miranda, Darrell J. Irvine, Gerhard Wunderlich

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Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models by Adrienne Rothschilds, Alice Tzeng, Naveen K. Mehta, Kelly D. Moynihan, Darrell J. Irvine, K. Dane Wittrup

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Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agents for a Plasmodium vivax malaria vaccine. by James J Moon, Heikyung Suh, Mark E Polhemus, Christian F Ockenhouse, Anjali Yadava, Darrell J Irvine

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IgG-Engineered Protective Antigen for Cytosolic Delivery of Proteins into Cancer Cells by Zeyu Lu, Nicholas L. Truex, Mariane B. Melo, Yiran Cheng, Na Li, Darrell J. Irvine, Bradley L. Pentelute

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High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function. by Maria Hottelet Foley, Talitha Forcier, Elizabeth McAndrew, Michael Gonzalez, Huabiao Chen, Boris Juelg, Bruce D Walker, Darrell J Irvine

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Temporal dynamics of intradermal cytokine response to tuberculin in Mycobacterium bovis BCG-vaccinated cattle using sampling microneedles by Sabine Steinbach, Sasan Jalili-Firoozinezhad, Sreenidhi Srinivasan, Mariane B. Melo, Sonya Middleton, Timm Konold, Michael Coad, Paula T. Hammond, Darrell J. Irvine, Martin Vordermeier, Vivek Kapur

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Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors by Antonio E. Barberio, Sean G. Smith, Ivan S. Pires, Sonia Iyer, Ferenc Reinhardt, Mariane B. Melo, Heikyung Suh, Robert A. Weinberg, Darrell J. Irvine, Paula T. Hammond

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Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells by Nicholas L. Truex, Aurélie Rondon, Simon L. Rössler, Cameron C. Hanna, Yehlin Cho, Bin-You Wang, Coralie M. Backlund, Emi A. Lutz, Darrell J. Irvine, Bradley L. Pentelute

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Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway by Sudha Kumari, David Depoil, Roberta Martinelli, Edward Judokusumo, Guillaume Carmona, Frank B Gertler, Lance C Kam, Christopher V Carman, Janis K Burkhardt, Darrell J Irvine, Michael L Dustin

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Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes. by Richard Brad Jones, Rachel O'Connor, Stefanie Mueller, Maria Foley, Gregory L Szeto, Dan Karel, Mathias Lichterfeld, Colin Kovacs, Mario A Ostrowski, Alicja Trocha, Darrell J Irvine, Bruce D Walker

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Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression by Kim Bich Nguyen, Malte Roerden, Christopher J Copeland, Coralie M Backlund, Nory G Klop-Packel, Tanaka Remba, Byungji Kim, Nishant K Singh, Michael E Birnbaum, Darrell J Irvine, Stefani Spranger

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T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity by Daniela Schmid, Chun Gwon Park, Christina A. Hartl, Nikita Subedi, Adam N. Cartwright, Regina Bou Puerto, Yiran Zheng, James Maiarana, Gordon J. Freeman, Kai W. Wucherpfennig, Darrell J. Irvine, Michael S. Goldberg

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Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy by Kristin L. Griffiths, Mushtaq Ahmed, Shibali Das, Radha Gopal, William Horne, Terry D. Connell, Kelly D. Moynihan, Jay K. Kolls, Darrell J. Irvine, Maxim N. Artyomov, Javier Rangel-Moreno, Shabaana A. Khader

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Cholesterol‐Amino‐Phosphate (CAP) Derived Lipid Nanoparticles for Delivery of Self‐Amplifying RNA and Restoration of Spermatogenesis in Infertile Mice by Shi Du, Wenqing Li, Yuebao Zhang, Yonger Xue, Xucheng Hou, Jingyue Yan, Jeffrey Cheng, Binbin Deng, David W. McComb, Jennifer Lin, Hong Zeng, Xiaolin Cheng, Darrell J. Irvine, Ron Weiss, Yizhou Dong

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Optimization of an alum-anchored clinical HIV vaccine candidate by Kristen A. Rodrigues, Christopher A. Cottrell, Jon M. Steichen, Bettina Groschel, Wuhbet Abraham, Heikyung Suh, Yash Agarwal, Kaiyuan Ni, Jason Y. H. Chang, Parisa Yousefpour, Mariane B. Melo, William R. Schief, Darrell J. Irvine

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Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma by Beth E. Grace, Beth E. Grace, Coralie M. Backlund, Coralie M. Backlund, Duncan M. Morgan, Duncan M. Morgan, Byong H. Kang, Byong H. Kang, Nishant K. Singh, Nishant K. Singh, Nishant K. Singh, Brooke D. Huisman, Brooke D. Huisman, C. Garrett Rappazzo, C. Garrett Rappazzo, Kelly D. Moynihan, Kelly D. Moynihan, Laura Maiorino, Laura Maiorino, Connor S. Dobson, Connor S. Dobson, Taeyoon Kyung, Taeyoon Kyung, Khloe S. Gordon, Khloe S. Gordon, Patrick V. Holec, Patrick V. Holec, Overbeck C. Takou Mbah, Daniel Garafola, Shengwei Wu, J. Christopher Love, J. Christopher Love, J. Christopher Love, K. Dane Wittrup, K. Dane Wittrup, K. Dane Wittrup, Darrell J. Irvine, Darrell J. Irvine, Darrell J. Irvine, Michael E. Birnbaum, Michael E. Birnbaum, Michael E. Birnbaum

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LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing by Yonger Xue, Yuebao Zhang, Yichen Zhong, Shi Du, Xucheng Hou, Wenqing Li, Haoyuan Li, Siyu Wang, Chang Wang, Jingyue Yan, Diana D. Kang, Binbin Deng, David W. McComb, Darrell J. Irvine, Ron Weiss, Yizhou Dong

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