Daved H. Fremont
Daved H. Fremont (born January 13, 1964) is a professor at the Washington University School of Medicine in St. Louis with dual appointments in the Departments of Pathology and Immunology/Biochemistry and Molecular Biophysics. He is currently director of the Computational and Molecular Biophysics Program. Fremont is also a principal investigator in the Center for Structural Genomics of Infectious Disease and his laboratory has deposited structures of proteins from several major human pathogens to the protein data bank (PDB).In 1993, Fremont received his Ph.D. in chemistry working in Ian Wilson's laboratory at The Scripps Research Institute while a student at the University of California, San Diego.
In 1998, he joined Washington University in St. Louis as an assistant professor where his research expanded to include viral immune evasion and antibody-mediated neutralization. His laboratory has since established the structural basis for interactions between host cytokines and poxviruses and herpesviruses decoy receptors and neutralization of West Nile virus by therapeutic antibodies. Fremont is now best known for his research on how the immune system recognizes viruses and the subversion mechanisms they deploy to avoid detection and clearance.
On the personal side, Fremont is married and has a daughter. He enjoys playing Go and poker; in the latter, he is partial to seven card stud, especially the Chesterfield version, and does not prefer wild card games. Provided by Wikipedia
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A molecular understanding of alphavirus entry. by Autumn C Holmes, Katherine Basore, Daved H Fremont, Michael S Diamond
Published 2020-10-01
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Enhancing the therapeutic activity of hyperimmune IgG against chikungunya virus using FcγRIIIa affinity chromatography by Julie M. Fox, Julie M. Fox, Vicky Roy, Bronwyn M. Gunn, Glen R. Bolton, Daved H. Fremont, Daved H. Fremont, Galit Alter, Galit Alter, Michael S. Diamond, Michael S. Diamond, Michael S. Diamond, Austin W. Boesch
Published 2023-05-01
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Structural mechanism of ER retrieval of MHC class I by cowpox. by William H McCoy, Xiaoli Wang, Wayne M Yokoyama, Ted H Hansen, Daved H Fremont
Published 2012-01-01
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Epitope Mapping of Japanese Encephalitis Virus Neutralizing Antibodies by Native Mass Spectrometry and Hydrogen/Deuterium Exchange by Jagat Adhikari, James Heffernan, Melissa Edeling, Estefania Fernandez, Prashant N. Jethva, Michael S. Diamond, Daved H. Fremont, Michael L. Gross
Published 2024-03-01
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A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy by Ahmed O. Hassan, Igor P. Dmitriev, Elena A. Kashentseva, Haiyan Zhao, Douglas E. Brough, Daved H. Fremont, David T. Curiel, Michael S. Diamond
Published 2019-09-01
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Capturing a flavivirus pre-fusion intermediate. by Bärbel Kaufmann, Paul R Chipman, Heather A Holdaway, Syd Johnson, Daved H Fremont, Richard J Kuhn, Michael S Diamond, Michael G Rossmann
Published 2009-11-01
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Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope. by S Kyle Austin, Kimberly A Dowd, Bimmi Shrestha, Christopher A Nelson, Melissa A Edeling, Syd Johnson, Theodore C Pierson, Michael S Diamond, Daved H Fremont
Published 2012-01-01
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Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy by Reza Ghasemi, Eric Lazear, Xiaoli Wang, Saeed Arefanian, Alexander Zheleznyak, Beatriz M. Carreno, Ryuji Higashikubo, Andrew E. Gelman, Daniel Kreisel, Daved H. Fremont, Alexander Sasha Krupnick
Published 2016-09-01
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Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors by Jun Wu, Karen Krchma, Hyung Joo Lee, Sairam Prabhakar, Xiaoli Wang, Haiyong Zhao, Xiaoyun Xing, Rho H. Seong, Daved H. Fremont, Maxim N. Artyomov, Ting Wang, Kyunghee Choi
Published 2020-11-01
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Progression of SARS-CoV-2 Seroprevalence in St. Louis, Missouri, through January 2021 by Brittany K. Smith, Andrew B. Janowski, Arim C. Fremont, Lucas J. Adams, Ya-Nan Dai, Christopher W. Farnsworth, Ann M. Gronowski, Stephen M. Roper, David Wang, Daved H. Fremont
Published 2021-08-01
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The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1. by Bimmi Shrestha, James D Brien, Soila Sukupolvi-Petty, S Kyle Austin, Melissa A Edeling, Taekyung Kim, Katie M O'Brien, Christopher A Nelson, Syd Johnson, Daved H Fremont, Michael S Diamond
Published 2010-04-01
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Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus by Estefania Fernandez, Nurgun Kose, Melissa A. Edeling, Jagat Adhikari, Gopal Sapparapu, Susana M. Lazarte, Christopher A. Nelson, Jennifer Govero, Michael L. Gross, Daved H. Fremont, James E. Crowe, Michael S. Diamond
Published 2018-03-01
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The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors. by Ravi F Iyer, David M Edwards, Philipp Kolb, Hans-Peter Raué, Chris A Nelson, Megan L Epperson, Mark K Slifka, Jeffrey C Nolz, Hartmut Hengel, Daved H Fremont, Klaus Früh
Published 2022-09-01
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