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David A. Sinclair

Sinclair in 2020

David Andrew Sinclair (born June 26, 1969) is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and the founding director of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard. He is the co-author of ''Lifespan: Why We Age – and Why We Don't Have To.'' Provided by Wikipedia

1

Can artificial intelligence identify effective COVID‐19 therapies? by Michael B Schultz, Daniel Vera, David A Sinclair

Published 2020-07-01

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2

Novel feature selection methods for construction of accurate epigenetic clocks. by Adam Li, Amber Mueller, Brad English, Anthony Arena, Daniel Vera, Alice E Kane, David A Sinclair

Published 2022-08-01

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3

Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers by Golam M. Uddin, Neil A. Youngson, Sabiha S. Chowdhury, Christopher Hagan, David A. Sinclair, Margaret J. Morris

Published 2020-03-01

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4

The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice by Qing-Shuo Zhang, Matthew Deater, Kathryn Schubert, Laura Marquez-Loza, Carl Pelz, David A. Sinclair, Markus Grompe

Published 2015-07-01

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5

Sex dimorphism and tissue specificity of gene expression changes in aging mice by Dantong Zhu, Matt Arnold, Brady A. Samuelson, Judy Z. Wu, Amber Mueller, David A. Sinclair, Alice E. Kane

Published 2024-10-01

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6

Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila by Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, Jordan Rabasco, Felipe Escobedo, Zhongyuan Zuo, Ben Brown, Susan Celniker, David A Sinclair, Hugo J Bellen, Norbert Perrimon

Published 2022-11-01

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7

NMN Supplementation Rescues Fertility and Bone Strength in Chemotherapy-Treated Mice by Maria B. MARINOVA, Wing-Hong Jonathan HO, Michael J. BERTOLDO, Vedran LOVRIC, Kaisa SELESNIEMI, William R. WALSH, David A. SINCLAIR, Kirsty WALTERS, Robert B. GILCHRIST, Lindsay E. WU

Published 2022-09-01

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8

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. by Ron Firestein, Gil Blander, Shaday Michan, Philipp Oberdoerffer, Shuji Ogino, Jennifer Campbell, Anupama Bhimavarapu, Sandra Luikenhuis, Rafael de Cabo, Charles Fuchs, William C Hahn, Leonard P Guarente, David A Sinclair

Published 2008-04-01

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9

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mic... by Stefano Tarantini, Marta Noa Valcarcel-Ares, Peter Toth, Andriy Yabluchanskiy, Zsuzsanna Tucsek, Tamas Kiss, Peter Hertelendy, Michael Kinter, Praveen Ballabh, Zoltán Süle, Eszter Farkas, Joseph A. Baur, David A. Sinclair, Anna Csiszar, Zoltan Ungvari

Published 2019-06-01

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10

Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion chromatography by Juan A. Martínez‐Greene, Karina Hernández‐Ortega, Ricardo Quiroz‐Baez, Osbaldo Resendis‐Antonio, Israel Pichardo‐Casas, David A. Sinclair, Bogdan Budnik, Alfredo Hidalgo‐Miranda, Eileen Uribe‐Querol, María del Pilar Ramos‐Godínez, Eduardo Martínez‐Martínez

Published 2021-04-01

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11

Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice by Sara Santos Franco, Luigia De Falco, Saghi Ghaffari, Carlo Brugnara, David A. Sinclair, Alessandro Matte’, Achille Iolascon, Narla Mohandas, Mariarita Bertoldi, Xiuli An, Angela Siciliano, Pauline Rimmelé, Maria Domenica Cappellini, Shaday Michan, Elisa Zoratti, Janin Anne, Lucia De Franceschi

Published 2014-02-01

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12

Cellular rejuvenation protects neurons from inflammation-mediated cell death by Sienna S. Drake, Abdulshakour Mohammadnia, Aliyah Zaman, Christine Gianfelice, Kali Heale, Adam M.R. Groh, Elizabeth M.-L. Hua, Matthew A. Hintermayer, Yuancheng Ryan Lu, David Gosselin, Stephanie Zandee, Alexandre Prat, Jo Anne Stratton, David A. Sinclair, Alyson E. Fournier

Published 2025-02-01

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13

Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice by Devin Wahl, Samantha M. Solon-Biet, Qiao-Ping Wang, Jibran A. Wali, Tamara Pulpitel, Ximonie Clark, David Raubenheimer, Alistair M. Senior, David A. Sinclair, Gregory J. Cooney, Rafael de Cabo, Victoria C. Cogger, Stephen J. Simpson, David G. Le Couteur

Published 2018-11-01

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14

#389 : Fertility Preservation During Chemotherapy Treatment by NAD+ Repletion in Mice by Robert Gilchrist, Wing-Hong Jonathan Ho, Maria B Marinova, Dave R Listijono, Michael J Bertoldo, Dulama Richani, Kim Lynn-Jee, Amelia Brown, Angelique H Riepsamen, Safaa Cabot, Sonia Bustamante, Ling Zhong, Kaisa Selesniemi, Derek Wong, Dale M Goss, Catherine Li, Toshiyuki Araki, David J Livingston, Nigel Turner, David A Sinclair, Kirsty A Walters, Hayden A Homer, Lindsay E Wu

Published 2023-12-01

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15

Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome by Wing-Hong Jonathan Ho, Maria B Marinova, Dave R Listijono, Michael J Bertoldo, Dulama Richani, Lynn-Jee Kim, Amelia Brown, Angelique H Riepsamen, Safaa Cabot, Emily R Frost, Sonia Bustamante, Ling Zhong, Kaisa Selesniemi, Derek Wong, Romanthi Madawala, Maria Marchante, Dale M Goss, Catherine Li, Toshiyuki Araki, David J Livingston, Nigel Turner, David A Sinclair, Kirsty A Walters, Hayden A Homer, Robert B Gilchrist, Lindsay E Wu

Published 2024-08-01

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