Nuclear Regulation of Wnt/β-Catenin Signaling: It’s a Complex Situation by Christin C. Anthony, David J. Robbins, Yashi Ahmed, Ethan Lee

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Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer by Fan Yang, Daniel T. Wynn, Chen Shen, Nagi G. Ayad, David J. Robbins

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NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis by Elena Shersher, Mohini Lahiry, Annamil Alvarez-Trotta, Giulia Diluvio, David J. Robbins, Ramin Shiekhattar, Anthony J. Capobianco

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Casein Kinase 1α as a Regulator of Wnt-Driven Cancer by Chen Shen, Anmada Nayak, Ricardo A. Melendez, Daniel T. Wynn, Joshua Jackson, Ethan Lee, Yashi Ahmed, David J. Robbins

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The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression by Emily F. Winterbottom, Devin C. Koestler, Dennis Liang Fei, Eric Wika, Anthony J. Capobianco, Carmen J. Marsit, Margaret R. Karagas, David J. Robbins

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Identification of a Family of Fatty-Acid-Speciated Sonic Hedgehog Proteins, Whose Members Display Differential Biological Properties by Jun Long, Robert Tokhunts, William M. Old, Stephane Houel, Jezabel Rodgriguez-Blanco, Samer Singh, Neal Schilling, Anthony J. Capobianco, Natalie G. Ahn, David J. Robbins

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GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth by Emily F. Winterbottom, Dennis L. Fei, Devin C. Koestler, Camilla Giambelli, Eric Wika, Anthony J. Capobianco, Ethan Lee, Carmen J. Marsit, Margaret R. Karagas, David J. Robbins

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Opioids Impair Intestinal Epithelial Repair in HIV-Infected Humanized Mice by Jingjing Meng, Jingjing Meng, Santanu Banerjee, Santanu Banerjee, Li Zhang, Greg Sindberg, Shamsudheen Moidunny, Bin Li, David J. Robbins, Mohit Girotra, Bradley Segura, Sundaram Ramakrishnan, Sabita Roy, Sabita Roy

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Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner by Emily F. Winterbottom, Yuka Moroishi, Yuliya Halchenko, David A. Armstrong, Paul J. Beach, Quang P. Nguyen, Anthony J. Capobianco, Nagi G. Ayad, Carmen J. Marsit, Zhigang Li, Margaret R. Karagas, David J. Robbins

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Identification of a Paralog-Specific Notch1 Intracellular Domain Degron by Matthew R. Broadus, Tony W. Chen, Leif R. Neitzel, Victoria H. Ng, Jeanne N. Jodoin, Laura A. Lee, Adrian Salic, David J. Robbins, Anthony J. Capobianco, James G. Patton, Stacey S. Huppert, Ethan Lee

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Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis. by Bin Li, Colin A Flaveny, Camilla Giambelli, Dennis Liang Fei, Lu Han, Brian I Hang, Feng Bai, Xin-Hai Pei, Vania Nose, Oname Burlingame, Anthony J Capobianco, Darren Orton, Ethan Lee, David J Robbins

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The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6 by Zachary T. Spencer, Victoria H. Ng, Hassina Benchabane, Ghalia Saad Siddiqui, Deepesh Duwadi, Ben Maines, Jamal M. Bryant, Anna Schwarzkopf, Kai Yuan, Sara N. Kassel, Anant Mishra, Ashley Pimentel, Andres M. Lebensohn, Rajat Rohatgi, Scott A. Gerber, David J. Robbins, Ethan Lee, Yashi Ahmed

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling by Chen Shen, Anmada Nayak, Leif R. Neitzel, Amber A. Adams, Maya Silver-Isenstadt, Leah M. Sawyer, Hassina Benchabane, Huilan Wang, Nawat Bunnag, Bin Li, Daniel T. Wynn, Fan Yang, Marta Garcia-Contreras, Charles H. Williams, Sivanesan Dakshanamurthy, Charles C. Hong, Nagi G. Ayad, Anthony J. Capobianco, Yashi Ahmed, Ethan Lee, David J. Robbins

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The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling by Victoria H. Ng, Zachary Spencer, Leif R. Neitzel, Anmada Nayak, Matthew A. Loberg, Chen Shen, Sara N. Kassel, Heather K. Kroh, Zhenyi An, Christin C. Anthony, Jamal M. Bryant, Amanda Lawson, Lily Goldsmith, Hassina Benchabane, Amanda G. Hansen, Jingjing Li, Starina D’Souza, Andres M. Lebensohn, Rajat Rohatgi, William A. Weiss, Vivian L. Weiss, Charles Williams, Charles C. Hong, David J. Robbins, Yashi Ahmed, Ethan Lee

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