David B. Weiner

David B. Weiner is an American biomedical researcher at The Wistar Institute in Philadelphia, where he serves as executive vice president and director of the Vaccines and Immunotherapy Center. Weiner also holds the titles of WW Smith Distinguished Chair in Cancer Research and professor emeritus, Perelman School of Medicine at the University of Pennsylvania. Provided by Wikipedia
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  1. 1
    Novel Synthetic DNA Immunogens Targeting Latent Expressed Antigens of Epstein–Barr Virus Elicit Potent Cellular Responses and Inhibit Tumor Growth

    Novel Synthetic DNA Immunogens Targeting Latent Expressed Antigens of Epstein–Barr Virus Elicit Potent Cellular Responses and Inhibit Tumor Growth by Krzysztof Wojtak, Alfredo Perales-Puchalt, David B. Weiner

    Published 2019-05-01
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  2. 2
    Designed DNA-Encoded IL-36 Gamma Acts as a Potent Molecular Adjuvant Enhancing Zika Synthetic DNA Vaccine-Induced Immunity and Protection in a Lethal Challenge Model

    Designed DNA-Encoded IL-36 Gamma Acts as a Potent Molecular Adjuvant Enhancing Zika Synthetic DNA Vaccine-Induced Immunity and Protection in a Lethal Challenge Model by Lumena Louis, Megan C. Wise, Hyeree Choi, Daniel O. Villarreal, Kar Muthumani, David B. Weiner

    Published 2019-05-01
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  3. 3
    Incorporation of a Novel CD4+ Helper Epitope Identified from Aquifex aeolicus Enhances Humoral Responses Induced by DNA and Protein Vaccinations

    Incorporation of a Novel CD4+ Helper Epitope Identified from Aquifex aeolicus Enhances Humoral Responses Induced by DNA and Protein Vaccinations by Ziyang Xu, Neethu Chokkalingam, Edgar Tello-Ruiz, Susanne Walker, Daniel W. Kulp, David B. Weiner

    Published 2020-08-01
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  4. 4
    Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge.

    Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge. by Lauren A Hirao, David A Hokey, Matthew P Morrow, Maria N Jure-Kunkel, David B Weiner

    Published 2011-01-01
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  5. 5
    Correction: Induction of Intrahepatic HCV NS4B, NS5A and NS5B-Specific Cellular Immune Responses following Peripheral Immunization.

    Correction: Induction of Intrahepatic HCV NS4B, NS5A and NS5B-Specific Cellular Immune Responses following Peripheral Immunization. by Krystle A. Lang Kuhs, Roberta Toporovski, Jian Yan, Arielle A. Ginsberg, Devon J. Shedlock, David B. Weiner

    Published 2013-01-01
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  6. 6
    REDD1 Is Essential for Optimal T Cell Proliferation and Survival.

    REDD1 Is Essential for Optimal T Cell Proliferation and Survival. by Emma L Reuschel, JiangFang Wang, Debra K Shivers, Karuppiah Muthumani, David B Weiner, Zhengyu Ma, Terri H Finkel

    Published 2015-01-01
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  7. 7
    Durability of response to VGX-3100 treatment of HPV16/18 positive cervical HSIL

    Durability of response to VGX-3100 treatment of HPV16/18 positive cervical HSIL by Prakash K. Bhuyan, Michael Dallas, Kim Kraynyak, Timothy Herring, Matthew Morrow, Jean Boyer, Susan Duff, Joseph Kim, David B. Weiner

    Published 2021-05-01
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  8. 8
    Elicitation of immune responses against Nipah virus by an engineered synthetic DNA vaccine

    Elicitation of immune responses against Nipah virus by an engineered synthetic DNA vaccine by Hyeree Choi, Sagar B. Kudchodkar, Ziyang Xu, Michelle Ho, Peng Xiao, Stephanie Ramos, Laurent Humeau, David B. Weiner, Kar Muthumani

    Published 2022-11-01
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  9. 9
    Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-delivered Genetic Adjuvants

    Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-delivered Genetic Adjuvants by Seleeke eFlingai, Matias eCzerwonko, Matias eCzerwonko, Jonathan eGoodman, Sagar B Kudchodkar, Kar eMuthumani, David B Weiner

    Published 2013-11-01
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  10. 10
    Synthetic DNA delivery by electroporation promotes robust in vivo sulfation of broadly neutralizing anti-HIV immunoadhesin eCD4-IgResearch in context

    Synthetic DNA delivery by electroporation promotes robust in vivo sulfation of broadly neutralizing anti-HIV immunoadhesin eCD4-IgResearch in context by Ziyang Xu, Megan C. Wise, Hyeree Choi, Alfredo Perales-Puchalt, Ami Patel, Edgar Tello-Ruiz, Jacqueline D. Chu, Kar Muthumani, David B. Weiner

    Published 2018-09-01
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  11. 11
    Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens.

    Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens. by Dominick J Laddy, Jian Yan, Michele Kutzler, Darwyn Kobasa, Gary P Kobinger, Amir S Khan, Jack Greenhouse, Niranjan Y Sardesai, Ruxandra Draghia-Akli, David B Weiner

    Published 2008-01-01
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  12. 12
    In vivo DNA-launched bispecific T cell engager targeting IL-13Rα2 controls tumor growth in an animal model of glioblastoma multiforme

    In vivo DNA-launched bispecific T cell engager targeting IL-13Rα2 controls tumor growth in an animal model of glioblastoma multiforme by Pratik S. Bhojnagarwala, Ryan P. O’Connell, Daniel Park, Kevin Liaw, Ali R. Ali, Devivasha Bordoloi, Joel Cassel, Nicholas J. Tursi, Ebony Gary, David B. Weiner

    Published 2022-09-01
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  13. 13
    Neutralization of hepatitis B virus by a novel DNA-encoded monoclonal antibody

    Neutralization of hepatitis B virus by a novel DNA-encoded monoclonal antibody by Urvi S. Zankharia, Sagar Kudchodkar, Makan Khoshnejad, Alfredo Perales-Puchalt, Hyeree Choi, Michelle Ho, Faraz Zaidi, Kenneth E. Ugen, Joseph J. Kim, David B. Weiner, Kar Muthumani

    Published 2020-09-01
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  14. 14
    Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity In Vivo

    Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity In Vivo by Makan Khoshnejad, Alfredo Perales-Puchalt, Yaya Dia, Peng Xiao, Ami Patel, Ziyang Xu, Xizhou Zhu, Kun Yun, Ishana Baboo, Rehman Qureshi, Laurent Humeau, Kar Muthumani, David B. Weiner

    Published 2020-09-01
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  15. 15
    Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity

    Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity by Devon J. Shedlock, Colleen Tingey, Lavanya Mahadevan, Natalie Hutnick, Emma L. Reuschel, Sagar Kudchodkar, Seleeke Flingai, Jenny Yan, Joseph J. Kim, Kenneth E. Ugen, David B. Weiner, Kar Muthumani

    Published 2014-03-01
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  16. 16
    IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment

    IL-33 delays metastatic peritoneal cancer progression inducing an allergic microenvironment by Alfredo Perales-Puchalt, Nikolaos Svoronos, Daniel O. Villarreal, Urvi Zankharia, Emma Reuschel, Krzysztof Wojtak, Kyle K. Payne, Elizabeth K. Duperret, Kar Muthumani, Jose R. Conejo-Garcia, David B. Weiner

    Published 2019-01-01
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  17. 17
    A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy

    A mAb against surface-expressed FSHR engineered to engage adaptive immunity for ovarian cancer immunotherapy by Devivasha Bordoloi, Pratik S. Bhojnagarwala, Alfredo Perales-Puchalt, Abhijeet J. Kulkarni, Xizhou Zhu, Kevin Liaw, Ryan P. O’Connell, Daniel H. Park, Daniel W. Kulp, Rugang Zhang, David B. Weiner

    Published 2022-11-01
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  18. 18
    Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses

    Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses by Laura K. Aisenberg, Kimberly E. Rousseau, Katherine Cascino, Guido Massaccesi, William H. Aisenberg, Wensheng Luo, Kar Muthumani, David B. Weiner, Stephen S. Whitehead, Michael A. Chattergoon, Anna P. Durbin, Andrea L. Cox

    Published 2022-06-01
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  19. 19
    Induction of Inflammation by West Nile virus Capsid through the Caspase-9 Apoptotic Pathway

    Induction of Inflammation by West Nile virus Capsid through the Caspase-9 Apoptotic Pathway by Joo-Sung Yang, Mathura P. Ramanathan, Karuppiah Muthumani, Andrew Y. Choo, Sung-Ha Jin, Qian-Chun Yu, Daniel S. Hwang, Daniel K. Choo, Mark D. Lee, Kesen Dang, J. Joseph Kim, David B. Weiner

    Published 2002-12-01
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  20. 20
    Engineered transfer RNAs for suppression of premature termination codons

    Engineered transfer RNAs for suppression of premature termination codons by John D. Lueck, Jae Seok Yoon, Alfredo Perales-Puchalt, Adam L. Mackey, Daniel T. Infield, Mark A. Behlke, Marshall R. Pope, David B. Weiner, William R. Skach, Paul B. McCray, Christopher A. Ahern

    Published 2019-02-01
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