Indomethacin-Induced Apoptosis in Esophageal Adenocarcinoma Cells Involves Upregulation of Bax and Translocation of Mitochondrial Cytochrome C Independent of COX-2 Expression by Sanjeev Aggarwal, Neelam Taneja, Lin Lin, Mark B. Orringer, Alnawaz Rehemtulla, David G. Beer

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Isoform alterations in the ubiquitination machinery impacting gastrointestinal malignancies by Srimathi Kasturirangan, Derek J. Nancarrow, Ayush Shah, Kiran H. Lagisetty, Theodore S. Lawrence, David G. Beer, Dipankar Ray

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Cytochromes P450 are Expressed in Proliferating Cells in Barrett's Metaplasia by Steven J. Hughes, Mark A. Morse, Christopher M. Weghorst, Hyesook Kim, Paul B. Watkins, F. Peter Guengerich, Mark B. Orringer, David G. Beer

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LINC00857 Interacting with YBX1 to Regulate Apoptosis and Autophagy via MET and Phosphor-AMPKa Signaling by Wenmei Su, Lihui Wang, Huijie Zhao, Shengmin Hu, Yi Zhou, Chunfang Guo, Bin Wu, Lixia Li, Zhixiong Yang, David G. Beer, Guoan Chen

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Regulation of EGFR Protein Stability by the HECT-type Ubiquitin Ligase SMURF2 by Dipankar Ray, Aarif Ahsan, Abigail Helman, Guoan Chen, Ashok Hegde, Susmita Ramanand Gurjar, Lili Zhao, Hiroaki Kiyokawa, David G Beer, Theodore S Lawrence, Mukesh K Nyati

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Overexpression of LINC00152 correlates with poor patient survival and knockdown impairs cell proliferation in lung cancer by Shumei Feng, Jie Zhang, Wenmei Su, Shengbin Bai, Lei Xiao, Xiuyuan Chen, Jules Lin, Rishindra M. Reddy, Andrew C. Chang, David G. Beer, Guoan Chen

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Collagen modifying enzyme P4HA1 is overexpressed and plays a role in lung adenocarcinoma by Alyncia D. Robinson, Balabhadrapatruni V.S.K. Chakravarthi, Sumit Agarwal, Darshan Shimoga Chandrashekar, Mackenzie L. Davenport, Guoan Chen, Upender Manne, David G. Beer, Mick D. Edmonds, Sooryanarayana Varambally

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L-Type Amino Acid Transporter-1 Overexpression and Melphalan Sensitivity in Barrett's Adenocarcinoma by Jules Lin, Duna A. Raoof, Dafydd G. Thomas, Joel K. Greenson, Thomas J. Giordano, Gregory S. Robinson, Maureen J. Bourner, Christopher T. Bauer, Mark B. Orringer, David G. Beer

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Clinically relevant characterization of lung adenocarcinoma subtypes based on cellular pathways: an international validation study. by Christopher M Bryant, Daniel L Albertus, Sinae Kim, Guoan Chen, Christian Brambilla, Mickael Guedj, Chinatsu Arima, William D Travis, Yasushi Yatabe, Takashi Takahashi, Elisabeth Brambilla, David G Beer

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Upregulated INHBA Expression May Promote Cell Proliferation and Is Associated with Poor Survival in Lung Adenocarcinoma by Christopher W. Seder, Wibisono Hartojo, Lin Lin, Amy L. Silvers, Zhuwen Wang, Dafydd G. Thomas, Thomas J. Giordano, Guoan Chen, Andrew C. Chang, Mark B. Orringer, David G. Beer

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Expression and Effect of Inhibition of the Ubiquitin-Conjugating Enzyme E2C on Esophageal Adenocarcinoma by Jules Lin, Duna A. Raoof, Zhuwen Wang, Mu-Yen Lin, Dafydd G. Thomas, Joel K. Greenson, Thomas J. Giordano, Mark B. Orringer, Andrew C. Chang, David G. Beer, Lin Lin

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Characterizing isoform switching events in esophageal adenocarcinoma by Yun Zhang, Katherine M. Weh, Connor L. Howard, Jean-Jack Riethoven, Jennifer L. Clarke, Kiran H. Lagisetty, Jules Lin, Rishindra M. Reddy, Andrew C. Chang, David G. Beer, Laura A. Kresty

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18F-FDG PET intensity correlates with a hypoxic gene signature and other oncogenic abnormalities in operable non-small cell lung cancer. by Brendan T Heiden, Guoan Chen, Matthew Hermann, Richard K J Brown, Mark B Orringer, Jules Lin, Andrew C Chang, Philip W Carrott, William R Lynch, Lili Zhao, David G Beer, Rishindra M Reddy

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Immune determinants of Barrett’s progression to esophageal adenocarcinoma by Kiran H. Lagisetty, Dyke P. McEwen, Derek J. Nancarrow, Johnathon G. Schiebel, Daysha Ferrer-Torres, Dipankar Ray, Timothy L. Frankel, Jules Lin, Andrew C. Chang, Laura A. Kresty, David G. Beer

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EML4-ALK Fusion Lung Cancer: A Rare Acquired Event by Sven Perner, Patrick L Wagner, Francesca Demichelis, Rohit Mehra, Christopher J LaFargue, Benjamin J Moss, Stefanie Arbogast, Alex Soltermann, Walter Weder, Thomas J Giordano, David G Beer, David S Rickman, Arul M Chinnaiyan, Holger Moch, Mark A Rubin

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Proteomic Analysis of Cytokeratin Isoforms Uncovers Association with Survival in Lung Adenocarcinoma by Tarek G. Gharib, Guoan Chen, Hong Wang, Chiang-Ching Huang, Michael S. Prescott, Kerby Shedden, David E. Misek, Dafydd G. Thomas, Thomas J. Giordano, Jeremy M.G. Taylor, Sharon Kardiat, John Yee, Mark B. Orringer, Samir Hanash, David G. Beer

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KRAS Protein Stability Is Regulated through SMURF2: UBCH5 Complex-Mediated β-TrCP1 Degradation by Shirish Shukla, Uday Sankar Allam, Aarif Ahsan, Guoan Chen, Pranathi Meda Krishnamurthy, Katherine Marsh, Matthew Rumschlag, Sunita Shankar, Christopher Whitehead, Matthew Schipper, Venkatesha Basrur, Daniel R. Southworth, Arul M. Chinnaiyan, Alnawaz Rehemtulla, David G. Beer, Theodore S. Lawrence, Mukesh K. Nyati, Dipankar Ray

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Genomic regions associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study. by Xiangqing Sun, Apoorva K Chandar, Marcia I Canto, Prashanthi N Thota, Malcom Brock, Nicholas J Shaheen, David G Beer, Jean S Wang, Gary W Falk, Prasad G Iyer, Julian A Abrams, Medha Venkat-Ramani, Martina Veigl, Alexander Miron, Joseph Willis, Deepa T Patil, Ilke Nalbantoglu, Kishore Guda, Sanford D Markowitz, Xiaofeng Zhu, Robert Elston, Amitabh Chak

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Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas. by Yuwei Zhang, Rodrigo Calado, Mahadev Rao, Julie A Hong, Alan K Meeker, Bogdan Dumitriu, Scott Atay, Peter J McCormick, Susan H Garfield, Danny Wangsa, Hesed M Padilla-Nash, Sandra Burkett, Mary Zhang, Tricia F Kunst, Nathan R Peterson, Sichuan Xi, Suzanne Inchauste, Nasser K Altorki, Alan G Casson, David G Beer, Curtis C Harris, Thomas Ried, Neal S Young, David S Schrump

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Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors by Daniel H. Hovelson, Andrew S. McDaniel, Andi K. Cani, Bryan Johnson, Kate Rhodes, Paul D. Williams, Santhoshi Bandla, Geoffrey Bien, Paul Choppa, Fiona Hyland, Rajesh Gottimukkala, Guoying Liu, Manimozhi Manivannan, Jeoffrey Schageman, Efren Ballesteros-Villagrana, Catherine S. Grasso, Michael J. Quist, Venkata Yadati, Anmol Amin, Javed Siddiqui, Bryan L. Betz, Karen E. Knudsen, Kathleen A. Cooney, Felix Y. Feng, Michael H. Roh, Peter S. Nelson, Chia-Jen Liu, David G. Beer, Peter Wyngaard, Arul M. Chinnaiyan, Seth Sadis, Daniel R. Rhodes, Scott A. Tomlins

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