Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer by Terese Geraghty, Anugraha Rajagopalan, Rabail Aslam, Alexander Pohlman, Ishwarya Venkatesh, Andrew Zloza, David Cimbaluk, David G. DeNardo, David G. DeNardo, David G. DeNardo, Vineet Gupta, Vineet Gupta

Get full text

Rethinking immune checkpoint blockade: ‘Beyond the T cell’ by Xiuting Liu, David G DeNardo, Graham D Hogg

Get full text

Tumor Microenvironment as a Regulator of Radiation Therapy: New Insights into Stromal-Mediated Radioresistance by Varintra E. Krisnawan, Jennifer A. Stanley, Julie K. Schwarz, David G. DeNardo

Get full text

Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer by Hui Peng, Lijin Li, Chong Zuo, Michael Y. Chen, Xiuli Zhang, Nancy B. Myers, Graham D. Hogg, David G. DeNardo, David G. DeNardo, S. Peter Goedegebuure, S. Peter Goedegebuure, William G. Hawkins, William G. Hawkins, William E. Gillanders, William E. Gillanders

Get full text

Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer by Julie G Grossman, Timothy M Nywening, Brian A Belt, Roheena Z Panni, Bradley A Krasnick, David G DeNardo, William G Hawkins, S Peter Goedegebuure, David C Linehan, Ryan C Fields

Get full text

Intratumoral T-cell receptor repertoire composition predicts overall survival in patients with pancreatic ductal adenocarcinoma by Vikram S. Pothuri, Graham D. Hogg, Leah Conant, Nicholas Borcherding, C. Alston James, Jacqueline Mudd, Greg Williams, Yongwoo David Seo, William G. Hawkins, Venu G. Pillarisetty, David G. DeNardo, Ryan C. Fields

Get full text

Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma by Arja Ray, Mackenzie K. Callaway, Nelson J. Rodríguez-Merced, Alexandra L. Crampton, Marjorie Carlson, Kenneth B. Emme, Ethan A. Ensminger, Alexander A. Kinne, Jonathan H. Schrope, Haley R. Rasmussen, Hong Jiang, David G. DeNardo, David K. Wood, Paolo P. Provenzano

Get full text

Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance by Melissa A. Meyer, John M. Baer, Brett L. Knolhoff, Timothy M. Nywening, Roheena Z. Panni, Xinming Su, Katherine N. Weilbaecher, William G. Hawkins, Cynthia Ma, Ryan C. Fields, David C. Linehan, Grant A. Challen, Roberta Faccio, Rebecca L. Aft, David G. DeNardo

Get full text

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis by Megan K. Ruhland, Andrew J. Loza, Aude-Helene Capietto, Xianmin Luo, Brett L. Knolhoff, Kevin C. Flanagan, Brian A. Belt, Elise Alspach, Kathleen Leahy, Jingqin Luo, Andras Schaffer, John R. Edwards, Gregory Longmore, Roberta Faccio, David G. DeNardo, Sheila A. Stewart

Get full text

Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response by Anthony Z. Wang, Jay A. Bowman-Kirigin, Rupen Desai, Liang-I Kang, Pujan R. Patel, Bhuvic Patel, Saad M. Khan, Diane Bender, M. Caleb Marlin, Jingxian Liu, Joshua W. Osbun, Eric C. Leuthardt, Michael R. Chicoine, Ralph G. Dacey, Gregory J. Zipfel, Albert H. Kim, David G. DeNardo, Allegra A. Petti, Gavin P. Dunn

Get full text

Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer by Ashenafi Bulle, Peng Liu, Kuljeet Seehra, Sapana Bansod, Yali Chen, Kiran Zahra, Vikas Somani, Iftikhar Ali Khawar, Hung-Po Chen, Paarth B. Dodhiawala, Lin Li, Yutong Geng, Chia-Kuei Mo, Jay Mahsl, Li Ding, Ramaswamy Govindan, Sherri Davies, Jacqueline Mudd, William G. Hawkins, Ryan C. Fields, David G. DeNardo, Deborah Knoerzer, Jason M. Held, Patrick M. Grierson, Andrea Wang-Gillam, Marianna B. Ruzinova, Kian-Huat Lim

Get full text

High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival by Erik P. Storrs, Prathamesh Chati, Abul Usmani, Ian Sloan, Bradley A. Krasnick, Ramandeep Babbra, Peter K. Harris, Chloe M. Sachs, Faridi Qaium, Deyali Chatterjee, Chris Wetzel, S. Peter Goedegebuure, Thomas Hollander, Hephzibah Anthony, Jennifer Ponce, Ateeq M. Khaliq, Shahed Badiyan, Hyun Kim, David G. Denardo, Gabriel D. Lang, Natalie D. Cosgrove, Vladimir M. Kushnir, Dayna S. Early, Ashiq Masood, Kian-Huat Lim, William G. Hawkins, Li Ding, Ryan C. Fields, Koushik K. Das, Aadel A. Chaudhuri

Get full text

Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop by Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Chowell, Lisa M. Coussens, Daniel D. De Carvalho, David G. DeNardo, Jérôme Galon, Howard L. Kaufman, Tomas Kirchhoff, Michael T. Lotze, Jason J. Luke, Andy J. Minn, Katerina Politi, Leonard D. Shultz, Richard Simon, Vésteinn Thórsson, Joanne B. Weidhaas, Maria Libera Ascierto, Paolo Antonio Ascierto, James M. Barnes, Valentin Barsan, Praveen K. Bommareddy, Adrian Bot, Sarah E. Church, Gennaro Ciliberto, Andrea De Maria, Dobrin Draganov, Winson S. Ho, Heather M. McGee, Anne Monette, Joseph F. Murphy, Paola Nisticò, Wungki Park, Maulik Patel, Michael Quigley, Laszlo Radvanyi, Harry Raftopoulos, Nils-Petter Rudqvist, Alexandra Snyder, Randy F. Sweis, Sara Valpione, Roberta Zappasodi, Lisa H. Butterfield, Mary L. Disis, Bernard A. Fox, Alessandra Cesano, Francesco M. Marincola, Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups

Get full text

Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop by Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Chowell, Lisa M. Coussens, Daniel D. De Carvalho, David G. DeNardo, Jérôme Galon, Howard L. Kaufman, Tomas Kirchhoff, Michael T. Lotze, Jason J. Luke, Andy J. Minn, Katerina Politi, Leonard D. Shultz, Richard Simon, Vésteinn Thórsson, Joanne B. Weidhaas, Maria Libera Ascierto, Paolo Antonio Ascierto, James M. Barnes, Valentin Barsan, Praveen K. Bommareddy, Adrian Bot, Sarah E. Church, Gennaro Ciliberto, Andrea De Maria, Dobrin Draganov, Winson S. Ho, Heather M. McGee, Anne Monette, Joseph F. Murphy, Paola Nisticò, Wungki Park, Maulik Patel, Michael Quigley, Laszlo Radvanyi, Harry Raftopoulos, Nils-Petter Rudqvist, Alexandra Snyder, Randy F. Sweis, Sara Valpione, Roberta Zappasodi, Lisa H. Butterfield, Mary L. Disis, Bernard A. Fox, Alessandra Cesano, Francesco M. Marincola, Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups

Get full text