Correspondence: Challenging a proposed role for TRPC5 in aortic baroreceptor pressure-sensing by Pratish Thakore, Susan D. Brain, David J. Beech

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Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site by David J. Wright, Katie J. Simmons, Rachel M. Johnson, David J. Beech, Stephen P. Muench, Robin S. Bon

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Remarkable Progress with Small-Molecule Modulation of TRPC1/4/5 Channels: Implications for Understanding the Channels in Health and Disease by Aisling Minard, Claudia C. Bauer, David J. Wright, Hussein N. Rubaiy, Katsuhiko Muraki, David J. Beech, Robin S. Bon

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ORAI1 Ca2+ Channel as a Therapeutic Target in Pathological Vascular Remodelling by Heba Shawer, Katherine Norman, Katherine Norman, Chew W. Cheng, Richard Foster, Richard Foster, David J. Beech, Marc A. Bailey

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Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells by Vincenza Caolo, Marjolaine Debant, Naima Endesh, T Simon Futers, Laeticia Lichtenstein, Fiona Bartoli, Gregory Parsonage, Elizabeth AV Jones, David J Beech

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Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels by Jian Shi, Adam J. Hyman, Dario De Vecchis, Jiehan Chong, Laeticia Lichtenstein, T. Simon Futers, Myriam Rouahi, Anne Negre Salvayre, Nathalie Auge, Antreas C. Kalli, David J. Beech

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Side-by-side comparison of published small molecule inhibitors against thapsigargin-induced store-operated Ca2+ entry in HEK293 cells by Katherine Norman, Karen E. Hemmings, Heba Shawer, Hollie L. Appleby, Alan J. Burnett, Nurasyikin Hamzah, Rajendra Gosain, Emily M. Woodhouse, David J. Beech, Richard Foster, Marc A. Bailey

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Side-by-side comparison of published small molecule inhibitors against thapsigargin-induced store-operated Ca2+ entry in HEK293 cells. by Katherine Norman, Karen E Hemmings, Heba Shawer, Hollie L Appleby, Alan J Burnett, Nurasyikin Hamzah, Rajendra Gosain, Emily M Woodhouse, David J Beech, Richard Foster, Marc A Bailey

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Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice by Fiona Bartoli, Elizabeth L. Evans, Nicola M. Blythe, Leander Stewart, Eulashini Chuntharpursat-Bon, Marjolaine Debant, Katie E. Musialowski, Laeticia Lichtenstein, Gregory Parsonage, T. Simon Futers, Neil A. Turner, David J. Beech

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Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity by Fiona Bartoli, Marjolaine Debant, Eulashini Chuntharpursat-Bon, Elizabeth L. Evans, Katie E. Musialowski, Gregory Parsonage, Lara C. Morley, T. Simon Futers, Piruthivi Sukumar, T. Scott Bowen, Mark T. Kearney, Laeticia Lichtenstein, Lee D. Roberts, David J. Beech

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Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy by Talia Caspi, Sam Straw, Chew Cheng, Jack O Garnham, Jason L. Scragg, Jessica Smith, Aaron O. Koshy, Eylem Levelt, Piruthivi Sukumar, John Gierula, David J. Beech, Mark T. Kearney, Richard M. Cubbon, Stephen B. Wheatcroft, Klaus K. Witte, Lee D. Roberts, T. Scott Bowen

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PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing by Eulashini Chuntharpursat-Bon, Oleksandr V. Povstyan, Melanie J. Ludlow, David J. Carrier, Marjolaine Debant, Jian Shi, Hannah J. Gaunt, Claudia C. Bauer, Alistair Curd, T. Simon Futers, Paul D. Baxter, Michelle Peckham, Stephen P. Muench, Antony Adamson, Neil Humphreys, Sarka Tumova, Robin S. Bon, Richard Cubbon, Laeticia Lichtenstein, David J. Beech

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Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development by Laura J. Brylka, Assil-Ramin Alimy, Miriam E. A. Tschaffon-Müller, Shan Jiang, Tobias Malte Ballhause, Anke Baranowsky, Simon von Kroge, Julian Delsmann, Eva Pawlus, Kian Eghbalian, Klaus Püschel, Astrid Schoppa, Melanie Haffner-Luntzer, David J. Beech, Frank Timo Beil, Michael Amling, Johannes Keller, Anita Ignatius, Timur A. Yorgan, Tim Rolvien, Thorsten Schinke

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Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance by Baptiste Rode, Jian Shi, Naima Endesh, Mark J. Drinkhill, Peter J. Webster, Sabine J. Lotteau, Marc A. Bailey, Nadira Y. Yuldasheva, Melanie J. Ludlow, Richard M. Cubbon, Jing Li, T. Simon Futers, Lara Morley, Hannah J. Gaunt, Katarzyna Marszalek, Hema Viswambharan, Kevin Cuthbertson, Paul D. Baxter, Richard Foster, Piruthivi Sukumar, Andrew Weightman, Sarah C. Calaghan, Stephen B. Wheatcroft, Mark T. Kearney, David J. Beech

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Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice by Cheukyau Luk, Katherine I. Bridge, Nele Warmke, Katie J. Simmons, Michael Drozd, Amy Moran, Amanda D. V. MacCannell, Chew W. Cheng, Sam Straw, Jason L. Scragg, Jessica Smith, Claire H. Ozber, Chloe G. Wilkinson, Anna Skromna, Natallia Makava, Hiran A. Prag, T. Simon Futers, Oliver I. Brown, Alexander-Francisco Bruns, Andrew MN Walker, Nicole T. Watt, Romana Mughal, Kathryn J. Griffin, Nadira Y. Yuldasheva, Sunti Limumpornpetch, Hema Viswambharan, Piruthivi Sukumar, David J. Beech, Antonio Vidal-Puig, Klaus K. Witte, Michael P. Murphy, Richard C. Hartley, Stephen B. Wheatcroft, Richard M. Cubbon, Lee D. Roberts, Mark T. Kearney, Natalie J. Haywood

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