The promise of gene editing: so close and yet so perilously far by David J. Segal

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Bacteria herald a new era of gene editing by David J Segal

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UBE3A: An E3 Ubiquitin Ligase With Genome-Wide Impact in Neurodevelopmental Disease by Simon Jesse Lopez, Simon Jesse Lopez, Simon Jesse Lopez, Simon Jesse Lopez, David J. Segal, David J. Segal, David J. Segal, David J. Segal, Janine M. LaSalle, Janine M. LaSalle, Janine M. LaSalle, Janine M. LaSalle

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Imaging Unique DNA Sequences in Individual Cells Using a CRISPR-Cas9-Based, Split Luciferase Biosensor by Nicholas G. Heath, Nicholas G. Heath, Nicholas G. Heath, Henriette O’Geen, Henriette O’Geen, Nicole B. Halmai, Nicole B. Halmai, Jacob E. Corn, Jacob E. Corn, David J. Segal, David J. Segal, David J. Segal

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Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators. by Henriette O'Geen, Chonghua Ren, Nicole B Coggins, Sofie L Bates, David J Segal

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Miz-1 activates gene expression via a novel consensus DNA binding motif. by Bonnie L Barrilleaux, Dana Burow, Sarah H Lockwood, Abigail Yu, David J Segal, Paul S Knoepfler

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The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres. by Amanda K Frank, Duy C Tran, Roy W Qu, Bradley A Stohr, David J Segal, Lifeng Xu

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UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons by S. Jesse Lopez, Keith Dunaway, M. Saharul Islam, Charles Mordaunt, Annie Vogel Ciernia, Makiko Meguro-Horike, Shin-ichi Horike, David J. Segal, Janine M. LaSalle

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Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner by Henriette O’Geen, Sofie L. Bates, Sakereh S. Carter, Karly A. Nisson, Julian Halmai, Kyle D. Fink, Suhn K. Rhie, Peggy J. Farnham, David J. Segal

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Unique Features of the Gut Microbiome Characterized in Animal Models of Angelman Syndrome by Ulrika Beitnere, Brayan Vilanova-Cuevas, Sarah G. Christian, Clint Taylor, Elizabeth L. Berg, Nycole A. Copping, Scott V. Dindot, Jill L. Silverman, Mélanie G. Gareau, David J. Segal

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Allele-Specific Reduction of the Mutant Huntingtin Allele Using Transcription Activator-Like Effectors in Human Huntington's Disease Fibroblasts by Kyle D. Fink Ph.D, Peter Deng, Josh Gutierrez, Joseph S. Anderson, Audrey Torrest, Anvita Komarla, Stefanos Kalomoiris, Whitney Cary, Johnathon D. Anderson, William Gruenloh, Alexandra Duffy, Teresa Tempkin, Geralyn Annett, Vicki Wheelock, David J. Segal, Jan A. Nolta

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Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation by Jai Woong Seo, Elizabeth S. Ingham, Lisa Mahakian, Spencer Tumbale, Bo Wu, Sadaf Aghevlian, Shahin Shams, Mo Baikoghli, Poorva Jain, Xiaozhe Ding, Nick Goeden, Tatyana Dobreva, Nicholas C. Flytzanis, Michael Chavez, Kratika Singhal, Ryan Leib, Michelle L. James, David J. Segal, R. Holland Cheng, Eduardo A. Silva, Viviana Gradinaru, Katherine W. Ferrara

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An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models by Peter Deng, Peter Deng, Peter Deng, Peter Deng, Julian A. N. M. Halmai, Julian A. N. M. Halmai, Julian A. N. M. Halmai, Ulrika Beitnere, David Cameron, David Cameron, David Cameron, Michele L. Martinez, Charles C. Lee, Jennifer J. Waldo, Jennifer J. Waldo, Jennifer J. Waldo, Krista Thongphanh, Krista Thongphanh, Anna Adhikari, Nycole Copping, Stela P. Petkova, Ruth D. Lee, Samantha Lock, Samantha Lock, Samantha Lock, Miranda Palomares, Henriette O’Geen, Jasmine Carter, Jasmine Carter, Jasmine Carter, Casiana E. Gonzalez, Casiana E. Gonzalez, Casiana E. Gonzalez, Fiona K. B. Buchanan, Fiona K. B. Buchanan, Fiona K. B. Buchanan, Johnathan D. Anderson, Fernando A. Fierro, Jan A. Nolta, Alice F. Tarantal, Jill L. Silverman, David J. Segal, Kyle D. Fink, Kyle D. Fink, Kyle D. Fink

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