David M. Knipe

David Mahan Knipe is the Higgins Professor of Microbiology and Molecular Genetics in the Department of Microbiology at the Harvard Medical School in Boston, Massachusetts and co-chief editor of the reference book Fields Virology. He returned to the Chair of the Program in Virology at Harvard Medical School in 2019, having previously held the position from 2004 through 2016 and served as interim Co-Chair of the Microbiology and Immunobiology Department from 2016 through 2018. Provided by Wikipedia
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  1. 1
    Herpes Simplex Virus 1 Manipulates Host Cell Antiviral and Proviral DNA Damage Responses

    Herpes Simplex Virus 1 Manipulates Host Cell Antiviral and Proviral DNA Damage Responses by Max E. Mertens, David M. Knipe

    Published 2021-02-01
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  2. 2
    Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection

    Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection by Philipp E. Merkl, David M. Knipe

    Published 2019-02-01
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  3. 3
    Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters

    Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters by Hyung Suk Oh, Paula Traktman, David M. Knipe

    Published 2015-07-01
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  4. 4
    Kinetics of Facultative Heterochromatin and Polycomb Group Protein Association with the Herpes Simplex Viral Genome during Establishment of Latent Infection

    Kinetics of Facultative Heterochromatin and Polycomb Group Protein Association with the Herpes Simplex Viral Genome during Establishment of Latent Infection by Anna R. Cliffe, Donald M. Coen, David M. Knipe

    Published 2013-03-01
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  5. 5
    Cellular SNF2H Chromatin-Remodeling Factor Promotes Herpes Simplex Virus 1 Immediate-Early Gene Expression and Replication

    Cellular SNF2H Chromatin-Remodeling Factor Promotes Herpes Simplex Virus 1 Immediate-Early Gene Expression and Replication by Kevin F. Bryant, Robert C. Colgrove, David M. Knipe

    Published 2011-03-01
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  6. 6
    ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress

    ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress by Joseph M Cabral, Hyung Suk Oh, David M Knipe

    Published 2018-11-01
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  7. 7
    Vaccination Route as a Determinant of Protective Antibody Responses against Herpes Simplex Virus

    Vaccination Route as a Determinant of Protective Antibody Responses against Herpes Simplex Virus by Clare Burn Aschner, Carl Pierce, David M. Knipe, Betsy C. Herold

    Published 2020-06-01
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  8. 8
    Sp1 facilitates continued HSV-1 gene expression in the absence of key viral transactivators

    Sp1 facilitates continued HSV-1 gene expression in the absence of key viral transactivators by Catherine N. Sodroski, Hyung Suk Oh, Shu-Fan Chou, David M. Knipe

    Published 2024-03-01
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  9. 9
    ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection.

    ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection. by Joseph M Cabral, Camille H Cushman, Catherine N Sodroski, David M Knipe

    Published 2021-04-01
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  10. 10
    Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes.

    Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes. by Tejaswini S Reddi, Philipp E Merkl, So-Yon Lim, Norman L Letvin, David M Knipe

    Published 2021-02-01
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  11. 11
    Roles of the Nuclear Lamina in Stable Nuclear Association and Assembly of a Herpesviral Transactivator Complex on Viral Immediate-Early Genes

    Roles of the Nuclear Lamina in Stable Nuclear Association and Assembly of a Herpesviral Transactivator Complex on Viral Immediate-Early Genes by Lindsey Silva, Hyung Suk Oh, Lynne Chang, Zhipeng Yan, Steven J. Triezenberg, David M. Knipe

    Published 2012-03-01
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  12. 12
    A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin

    A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin by Priya Raja, Jennifer S. Lee, Dongli Pan, Jean M. Pesola, Donald M. Coen, David M. Knipe

    Published 2016-07-01
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  13. 13
    CCCTC-Binding Factor Acts as a Heterochromatin Barrier on Herpes Simplex Viral Latent Chromatin and Contributes to Poised Latent Infection

    CCCTC-Binding Factor Acts as a Heterochromatin Barrier on Herpes Simplex Viral Latent Chromatin and Contributes to Poised Latent Infection by Jennifer S. Lee, Priya Raja, Dongli Pan, Jean M. Pesola, Donald M. Coen, David M. Knipe

    Published 2018-03-01
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  14. 14
    Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9

    Herpesviral lytic gene functions render the viral genome susceptible to novel editing by CRISPR/Cas9 by Hyung Suk Oh, Werner M Neuhausser, Pierce Eggan, Magdalena Angelova, Rory Kirchner, Kevin C Eggan, David M Knipe

    Published 2019-12-01
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  15. 15
    IFNγ is a central node of cancer immune equilibrium

    IFNγ is a central node of cancer immune equilibrium by Michael J. Walsh, Courtney T. Stump, Rakeeb Kureshi, Patrick Lenehan, Lestat R. Ali, Michael Dougan, David M. Knipe, Stephanie K. Dougan

    Published 2023-03-01
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  16. 16
    A Targeted RNA Interference Screen Reveals Novel Epigenetic Factors That Regulate Herpesviral Gene Expression

    A Targeted RNA Interference Screen Reveals Novel Epigenetic Factors That Regulate Herpesviral Gene Expression by Hyung Suk Oh, Kevin F. Bryant, Thomas J. F. Nieland, Aprotim Mazumder, Mukta Bagul, Mark Bathe, David E. Root, David M. Knipe

    Published 2014-02-01
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  17. 17
    Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs

    Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs by Dongli Pan, Gang Li, Jenna Morris-Love, Shuyuan Qi, Lei Feng, Max E. Mertens, Igor Jurak, David M. Knipe, Donald M. Coen

    Published 2019-02-01
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  18. 18
    HIV Integrase Inhibitors Block Replication of Alpha-, Beta-, and Gammaherpesviruses

    HIV Integrase Inhibitors Block Replication of Alpha-, Beta-, and Gammaherpesviruses by Zhipeng Yan, Kevin F. Bryant, Sean M. Gregory, Magdalena Angelova, David H. Dreyfus, Xue Zhi Zhao, Donald M. Coen, Terrence R. Burke, David M. Knipe

    Published 2014-08-01
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  19. 19
    Neuronal miR-9 promotes HSV-1 epigenetic silencing and latency by repressing Oct-1 and Onecut family genes

    Neuronal miR-9 promotes HSV-1 epigenetic silencing and latency by repressing Oct-1 and Onecut family genes by Yue Deng, Yuqi Lin, Siyu Chen, Yuhang Xiang, Hongjia Chen, Shuyuan Qi, Hyung Suk Oh, Biswajit Das, Gloria Komazin-Meredith, Jean M. Pesola, David M. Knipe, Donald M. Coen, Dongli Pan

    Published 2024-03-01
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  20. 20
    Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA

    Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA by Jan B. Boscheinen, Sabrina Thomann, David M. Knipe, Neal DeLuca, Beatrice Schuler-Thurner, Stefanie Gross, Jan Dörrie, Niels Schaft, Christian Bach, Anette Rohrhofer, Melanie Werner-Klein, Barbara Schmidt, Barbara Schmidt, Barbara Schmidt, Philipp Schuster

    Published 2019-01-01
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