Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1′-Biphenyl-2,2′,6,6′-tetrol per Richard C. Knighton, Krishna Sharma, Naomi S. Robertson, David R. Spring, Martin Wills

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Design and Synthesis of a Biotinylated Chemical Probe for Detecting the Molecular Targets of an Inhibitor of the Production of the Pseudomonas aeruginosa Virulence Factor Pyocyanin per Ysobel R. Baker, Warren R. J. D. Galloway, James T. Hodgkinson, David R. Spring

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Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products per Stephen M. Geddis, Teodora Coroama, Suzanne Forrest, James T. Hodgkinson, Martin Welch, David R. Spring

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Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections per Sarah L. Kidd, Thomas J. Osberger, Natalia Mateu, Hannah F. Sore, David R. Spring

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Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study per Eleanor L. Atkinson, Jessica Iegre, Paul D. Brear, Elizabeth A. Zhabina, Marko Hyvönen, David R. Spring

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Identification of key residues that confer Rhodobacter sphaeroides LPS activity at horse TLR4/MD-2. per Katherine L Irvine, Monique Gangloff, Catherine M Walsh, David R Spring, Nicholas J Gay, Clare E Bryant

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Microscopy and chemical analyses reveal flavone-based woolly fibres extrude from micron-sized holes in glandular trichomes of Dionysia tapetodes per Matthieu Bourdon, Josephine Gaynord, Karin H. Müller, Gareth Evans, Simon Wallis, Paul Aston, David R. Spring, Raymond Wightman

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Toxicity of six plant extracts and two pyridone alkaloids from Ricinus communis against the malaria vector Anopheles gambiae per Sabina Wangui Wachira, Sabar Omar, Julia Wanjiru Jacob, Martin Wahome, Hans T Alborn, David R Spring, Daniel K Masiga, Baldwyn Torto

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Combinatorial Synthesis of Structurally Diverse Triazole-Bridged Flavonoid Dimers and Trimers per Tze Han Sum, Tze Jing Sum, Warren R. J. D. Galloway, Súil Collins, David G. Twigg, Florian Hollfelder, David R. Spring

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Discovery of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells per Bernardas Morkunas, Balint Gal, Warren R. J. D. Galloway, James T. Hodgkinson, Brett M. Ibbeson, Yaw Sing Tan, Martin Welch, David R. Spring

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Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons per Elizabeth Bilsland, Tatyana A. Tavella, Renata Krogh, Jamie E. Stokes, Annabelle Roberts, James Ajioka, David R. Spring, Adriano D. Andricopulo, Fabio T. M. Costa, Stephen G. Oliver

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Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity per Meng Wang, Prasanthi Medarametla, Thales Kronenberger, Tomas Deingruber, Paul Brear, Wendy Figueroa, Pok-Man Ho, Thomas Krueger, James C. Pearce, Antti Poso, James G. Wakefield, David R. Spring, Martin Welch

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Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction per Krishna Sharma, Alexander V. Strizhak, Elaine Fowler, Wenshu Xu, Ben Chappell, Hannah F. Sore, Warren R. J. D. Galloway, Matthew N. Grayson, Yu Heng Lau, Laura S. Itzhaki, David R. Spring

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Development of a Novel Cell-Permeable Protein–Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1 per David J. Huggins, Bryn S. Hardwick, Pooja Sharma, Amy Emery, Luca Laraia, Fengzhi Zhang, Ana J. Narvaez, Meredith Roberts-Thomson, Alex T. Crooks, Robert G. Boyle, Richard Boyce, David W. Walker, Natalia Mateu, Grahame J. McKenzie, David R. Spring, Ashok R. Venkitaraman

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Novel immunotherapeutics against LGR5 to target multiple cancer types per Hung-Chang Chen, Nico Mueller, Katherine Stott, Chrysa Kapeni, Eilidh Rivers, Carolin M Sauer, Flavio Beke, Stephen J Walsh, Nicola Ashman, Louise O’Brien, Amir Rafati Fard, Arman Ghodsinia, Changtai Li, Fadwa Joud, Olivier Giger, Inti Zlobec, Ioana Olan, Sarah J Aitken, Matthew Hoare, Richard Mair, Eva Serrao, James D Brenton, Alicia Garcia-Gimenez, Simon E Richardson, Brian Huntly, David R Spring, Mikkel-Ole Skjoedt, Karsten Skjødt, Marc de la Roche, Maike de la Roche

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Publisher Correction: Novel immunotherapeutics against LGR5 to target multiple cancer types per Hung-Chang Chen, Nico Mueller, Katherine Stott, Chrysa Kapeni, Eilidh Rivers, Carolin M Sauer, Flavio Beke, Stephen J Walsh, Nicola Ashman, Louise O’Brien, Amir Rafati Fard, Arman Ghodsinia, Changtai Li, Fadwa Joud, Olivier Giger, Inti Zlobec, Ioana Olan, Sarah J Aitken, Matthew Hoare, Richard Mair, Eva Serrao, James D Brenton, Alicia Garcia-Gimenez, Simon E Richardson, Brian Huntly, David R Spring, Mikkel-Ole Skjoedt, Karsten Skjødt, Marc de la Roche, Maike de la Roche

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