In vitro and in vivo antimalarial activity and cytotoxicity of extracts, fractions and a substance isolated from the Amazonian plant Tachia grandiflora (Gentianaceae) by Luiz Francisco Rocha e Silva, Emerson Silva Lima, Marne Carvalho de Vasconcellos, Ellen Suzany Pereira Aranha, David Siqueira Costa, Elba Vieira Mustafa, Sabrina Kelly Reis de Morais, Maria das Gracas Costa Alecrim, Sergio Massayoshi Nunomura, Lena Struwe, Valter Ferreira de Andrade-Neto, Adrian Martin Pohlit

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