Neuroinflammation as a Factor of Neurodegenerative Disease: Thalidomide Analogs as Treatments by Yoo Jin Jung, David Tweedie, Michael T. Scerba, Nigel H. Greig

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Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α. by Lital Rachmany, David Tweedie, Vardit Rubovitch, Qian-Sheng Yu, Yazhou Li, Jia-Yi Wang, Chaim G Pick, Nigel H Greig

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Time-dependent cytokine and chemokine changes in mouse cerebral cortex following a mild traumatic brain injury by David Tweedie, Hanuma Kumar Karnati, Roger Mullins, Chaim G Pick, Barry J Hoffer, Edward J Goetzl, Dimitrios Kapogiannis, Nigel H Greig

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Changes in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury by David Tweedie, Lital Rachmany, Vardit Rubovitch, Yongqing Zhang, Kevin G. Becker, Evelyn Perez, Barry J. Hoffer, Chaim G. Pick, Nigel H. Greig

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A New Generation of IMiDs as Treatments for Neuroinflammatory and Neurodegenerative Disorders by Katherine O. Kopp, Margaret E. Greer, Elliot J. Glotfelty, Shih-Chang Hsueh, David Tweedie, Dong Seok Kim, Marcella Reale, Neil Vargesson, Nigel H. Greig

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Pomalidomide Improves Motor Behavioral Deficits and Protects Cerebral Cortex and Striatum Against Neurodegeneration Through a Reduction of Oxidative/Nitrosative Damages and Neuroin... by Ya-Ni Huang, Nigel H. Greig, Pen-Sen Huang, Yung-Hsiao Chiang, Alan Hoffer, Chih-Hao Yang, David Tweedie, Ying Chen, Ju-Chi Ou, Jia-Yi Wang

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Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brai... by Ling-Yu Yang, Nigel H. Greig, Ya-Ni Huang, Tsung-Hsun Hsieh, David Tweedie, Qian-Sheng Yu, Barry J. Hoffer, Yu Luo, Yu-Chieh Kao, Jia-Yi Wang

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The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia by Elliot J. Glotfelty, Luis B. Tovar-y-Romo, Shih-Chang Hsueh, David Tweedie, Yazhou Li, Brandon K. Harvey, Barry J. Hoffer, Tobias E. Karlsson, Lars Olson, Nigel H. Greig

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Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis. by Yazhou Li, Srinivasulu Chigurupati, Harold W Holloway, Mohamed Mughal, David Tweedie, Daniel A Bruestle, Mark P Mattson, Yun Wang, Brandon K Harvey, Balmiki Ray, Debomoy K Lahiri, Nigel H Greig

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(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice by Daniela Lecca, Miaad Bader, David Tweedie, Alexander F. Hoffman, Yoo Jin Jung, Shin-Chang Hsueh, Barry J. Hoffer, Robert E. Becker, Chaim G. Pick, Carl R. Lupica, Nigel H. Greig

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Activity of a Novel Anti-Inflammatory Agent F-3,6′-dithiopomalidomide as a Treatment for Traumatic Brain Injury by Shih Chang Hsueh, Michael T. Scerba, David Tweedie, Daniela Lecca, Dong Seok Kim, Abdul Mannan Baig, Yu Kyung Kim, Inho Hwang, Sun Kim, Warren R. Selman, Barry J. Hoffer, Nigel H. Greig

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Exendin-4 attenuates blast traumatic brain injury induced cognitive impairments, losses of synaptophysin and in vitro TBI-induced hippocampal cellular degeneration by Lital Rachmany, David Tweedie, Vardit Rubovitch, Yazhou Li, Harold W. Holloway, Dong Seok Kim, Whitney A. Ratliff, Jessica N. Saykally, Bruce A. Citron, Barry J. Hoffer, Nigel H. Greig, Chaim G. Pick

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Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury by Miaad Bader, Yazhou Li, Daniela Lecca, Vardit Rubovitch, David Tweedie, Elliot Glotfelty, Lital Rachmany, Hee Kyung Kim, Ho-Il Choi, Barry J. Hoffer, Chaim G. Pick, Nigel H. Greig, Dong Seok Kim

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Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs by Megan L. Peach, Shaunna L. Beedie, Cindy H. Chau, Matthew K. Collins, Suzana Markolovic, Weiming Luo, David Tweedie, Christian Steinebach, Nigel H. Greig, Michael Gütschow, Neil Vargesson, Marc C. Nicklaus, William D. Figg

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Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury by Daniela Lecca, Shih-Chang Hsueh, Weiming Luo, David Tweedie, Dong Seok Kim, Abdul Mannan Baig, Neil Vargesson, Yu Kyung Kim, Inho Hwang, Sun Kim, Barry J. Hoffer, Yung-Hsiao Chiang, Nigel H. Greig

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3,6’-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation by Chih-Tung Lin, Daniela Lecca, Ling-Yu Yang, Weiming Luo, Michael T Scerba, David Tweedie, Pen-Sen Huang, Yoo-Jin Jung, Dong Seok Kim, Chih-Hao Yang, Barry J Hoffer, Jia-Yi Wang, Nigel H Greig

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Pomalidomide Reduces Ischemic Brain Injury in Rodents by Yan-Rou Tsai, David Tweedie, Ignacio Navas-Enamorado, Michael T. Scerba, Cheng-Fu Chang, Jing-Huei Lai, John Chung-Che Wu, Yen-Hua Chen, Shuo-Jhen Kang, Barry J. Hoffer, Rafael de Cabo, Nigel H. Greig, Yung-Hsiao Chiang, Kai-Yun Chen

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Neuroprotective Effects and Treatment Potential of Incretin Mimetics in a Murine Model of Mild Traumatic Brain Injury by Miaad Bader, Yazhou Li, David Tweedie, Nathan A. Shlobin, Adi Bernstein, Vardit Rubovitch, Luis B. Tovar-y-Romo, Luis B. Tovar-y-Romo, Richard D. DiMarchi, Barry J. Hoffer, Nigel H. Greig, Chaim G. Pick, Chaim G. Pick, Chaim G. Pick

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Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanism... by David Tweedie, Koji Fukui, Yazhou Li, Qian-Sheng Yu, Shani Barak, Ian A Tamargo, Vardit Rubovitch, Harold W Holloway, Elin Lehrmann, William H Wood, Yongqing Zhang, Kevin G Becker, Evelyn Perez, Henriette Van Praag, Yu Luo, Barry J Hoffer, Robert E Becker, Chaim G Pick, Nigel H Greig

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3,6′- and 1,6′-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation by Yan-Rou Tsai, Dong Seok Kim, Shih-Chang Hsueh, Kai-Yun Chen, John Chung-Che Wu, Jia-Yi Wang, Yi-Syue Tsou, Inho Hwang, Yukyung Kim, Dayeon Gil, Eui Jung Jo, Baek-Soo Han, David Tweedie, Daniela Lecca, Michael T. Scerba, Warren R. Selman, Barry J. Hoffer, Nigel H. Greig, Yung-Hsiao Chiang

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