Synthesis of 2,4,6-Tris(4-N-isopropylamidinophenyl)pyrimidine trihydrochloride by David W. Boykin, Miroslav Bajić

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A New Generation of Minor-Groove-Binding—Heterocyclic Diamidines That Recognize G·C Base Pairs in an AT Sequence Context by Ananya Paul, Pu Guo, David W. Boykin, W. David Wilson

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Thermodynamic Factors That Drive Sequence-Specific DNA Binding of Designed, Synthetic Minor Groove Binding Agents by Ananya Paul, Abdelbasset A. Farahat, David W. Boykin, W. David Wilson

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Discovery of a novel, monocationic, small-molecule inhibitor of scrapie prion accumulation in cultured sheep microglia and Rov cells. by James B Stanton, David A Schneider, Kelcey D Dinkel, Bethany F Balmer, Timothy V Baszler, Bruce A Mathison, David W Boykin, Arvind Kumar

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Arylimidamides Have Potential for Chemoprophylaxis against Blood-Transmitted Chagas Disease by Bruno Lisboa Timm, Aline Nefertiti Silva da Gama, Marcos Meuser Batista, Denise da Gama Jaén Batista, David W. Boykin, Harry P. De Koning, Maria de Nazaré Correia Soeiro

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Induction of AML cell differentiation using HOXA9/DNA binding inhibitors as a potential therapeutic option for HOXA9‐dependent AML by Mélanie Lambert, Samy Jambon, Mohamed A. Bouhlel, Sabine Depauw, Julie Vrevin, Samuel Blanck, Guillemette Marot, Martin Figeac, Claude Preudhomme, Bruno Quesnel, David W. Boykin, Marie‐Hélène David‐Cordonnier

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Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis. by John K Thuita, Michael Z Wang, John M Kagira, Cathrine L Denton, Mary F Paine, Raymond E Mdachi, Grace A Murilla, Shelley Ching, David W Boykin, Richard R Tidwell, James E Hall, Reto Brun

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Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys. by John K Thuita, Kristina K Wolf, Grace A Murilla, Arlene S Bridges, David W Boykin, James N Mutuku, Qiang Liu, Susan K Jones, Charles O Gem, Shelley Ching, Richard R Tidwell, Michael Z Wang, Mary F Paine, Reto Brun

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Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis. by John K Thuita, Kristina K Wolf, Grace A Murilla, Qiang Liu, James N Mutuku, Yao Chen, Arlene S Bridges, Raymond E Mdachi, Mohamed A Ismail, Shelley Ching, David W Boykin, James Edwin Hall, Richard R Tidwell, Mary F Paine, Reto Brun, Michael Zhuo Wang

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Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies by Maria de Nazaré C Soeiro, Andréia P Dantas, Anissa Daliry, Cristiane F da Silva, Denise GJ Batista, Elen M de Souza, Gabriel M Oliveira, Kelly Salomão, Marcos Meuser Batista, Michelle GO Pacheco, Patrícia Bernardino da Silva, Ricardo M Santa-Rita, Rubem FS Menna Barreto, David W Boykin, Solange Lisboa de Castro

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G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo by Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert‐Jaramillo, Samir Abdelkarim, Emma L Clayton, Mica Clarke, Marie‐Therese Konrad, Andrew J Nicoll, Jamie S Mitchell, Andrea Calvo, Adriano Chio, Henry Houlden, James M Polke, Mohamed A Ismail, Chad E Stephens, Tam Vo, Abdelbasset A Farahat, W David Wilson, David W Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M Isaacs

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Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei by Ali H Alghamdi, Jane C Munday, Gustavo Daniel Campagnaro, Dominik Gurvic, Fredrik Svensson, Chinyere E Okpara, Arvind Kumar, Juan Quintana, Maria Esther Martin Abril, Patrik Milić, Laura Watson, Daniel Paape, Luca Settimo, Anna Dimitriou, Joanna Wielinska, Graeme Smart, Laura F Anderson, Christopher M Woodley, Siu Pui Ying Kelly, Hasan MS Ibrahim, Fabian Hulpia, Mohammed I Al-Salabi, Anthonius A Eze, Teresa Sprenger, Ibrahim A Teka, Simon Gudin, Simone Weyand, Mark Field, Christophe Dardonville, Richard R Tidwell, Mark Carrington, Paul O'Neill, David W Boykin, Ulrich Zachariae, Harry P De Koning

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