Editorial: Optimizing the first-line treatment for metastatic colorectal cancer by Davide Ciardiello, Angelica Petrillo

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The Interplay between Anti-Angiogenics and Immunotherapy in Colorectal Cancer by Brigida Anna Maiorano, Alessandro Parisi, Evaristo Maiello, Davide Ciardiello

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CAVE-2 (Cetuximab-AVElumab) mCRC: A Phase II Randomized Clinical Study of the Combination of Avelumab Plus Cetuximab as a Rechallenge Strategy in Pre-Treated RAS/BRAF Wild-Type mCR... by Stefania Napolitano, Giulia Martini, Davide Ciardiello, Davide Ciardiello, Massimo Di Maio, Nicola Normanno, Antonio Avallone, Erika Martinelli, Evaristo Maiello, Teresa Troiani, Fortunato Ciardiello

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Efficacy and safety of a biomarker-driven cetuximab-based treatment regimen over 3 treatment lines in mCRC patients with RAS/BRAF wild type tumors at start of first line: The CAPRI... by Giulia Martini, Davide Ciardiello, Davide Ciardiello, Stefania Napolitano, Erika Martinelli, Teresa Troiani, Tiziana Pia Latiano, Antonio Avallone, Nicola Normanno, Massimo Di Maio, Evaristo Maiello, Fortunato Ciardiello

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Case report of unusual synchronous anal and rectal squamous cell carcinoma: clinical and therapeutic lesson by Davide Ciardiello, Davide Ciardiello, Sara Del Tufo, Paola Parente, Antonietta Gerarda Gravina, Francesco Selvaggi, Iacopo Panarese, Renato Franco, Michele Caterino, Giulia Martini, Fortunato Ciardiello, Roberto Grassi, Salvatore Cappabianca, Alfonso Reginelli, Erika Martinelli

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Immune-Checkpoint Inhibitors in Advanced Bladder Cancer: Seize the Day by Brigida Anna Maiorano, Ugo De Giorgi, Davide Ciardiello, Giovanni Schinzari, Antonio Cisternino, Giampaolo Tortora, Evaristo Maiello

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Cancer Vaccines for Genitourinary Tumors: Recent Progresses and Future Possibilities by Brigida Anna Maiorano, Giovanni Schinzari, Davide Ciardiello, Maria Grazia Rodriquenz, Antonio Cisternino, Giampaolo Tortora, Evaristo Maiello

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Comprehensive Review on the Clinical Relevance of Long Non-Coding RNAs in Cutaneous Melanoma by Vincenzo De Falco, Stefania Napolitano, Daniela Esposito, Luigi Pio Guerrera, Davide Ciardiello, Luigi Formisano, Teresa Troiani

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Beyond Platinum, ICIs in Metastatic Cervical Cancer: A Systematic Review by Brigida Anna Maiorano, Mauro Francesco Pio Maiorano, Davide Ciardiello, Annamaria Maglione, Michele Orditura, Domenica Lorusso, Evaristo Maiello

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The Interplay between PARP Inhibitors and Immunotherapy in Ovarian Cancer: The Rationale behind a New Combination Therapy by Brigida Anna Maiorano, Domenica Lorusso, Mauro Francesco Pio Maiorano, Davide Ciardiello, Paola Parrella, Antonio Petracca, Gennaro Cormio, Evaristo Maiello

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Macrophage Migration Inhibitory Factor Is a Molecular Determinant of the Anti-EGFR Monoclonal Antibody Cetuximab Resistance in Human Colorectal Cancer Cells by Rosita Russo, Nunzia Matrone, Valentina Belli, Davide Ciardiello, Mariangela Valletta, Sabrina Esposito, Paolo Vincenzo Pedone, Fortunato Ciardiello, Teresa Troiani, Angela Chambery

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Multi-Omic Approaches in Colorectal Cancer beyond Genomic Data by Emilia Sardo, Stefania Napolitano, Carminia Maria Della Corte, Davide Ciardiello, Antonio Raucci, Gianluca Arrichiello, Teresa Troiani, Fortunato Ciardiello, Erika Martinelli, Giulia Martini

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Cutaneous Metastasis from Colorectal Cancer: Making Light on an Unusual and Misdiagnosed Event by Paola Parente, Davide Ciardiello, Luca Reggiani Bonetti, Vincenzo Famiglietti, Gerardo Cazzato, Stefania Caramaschi, Vito Attino, Diego Urbano, Giuseppe Di Maggio, Giuseppe Ingravallo

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Clinic, Endoscopic and Histological Features in Patients Treated with ICI Developing GI Toxicity: Some News and Reappraisal from a Mono-Institutional Experience by Paola Parente, Brigida Anna Maiorano, Davide Ciardiello, Francesco Cocomazzi, Sonia Carparelli, Maria Guerra, Giuseppe Ingravallo, Gerardo Cazzato, Illuminato Carosi, Evaristo Maiello, Fabrizio Bossa

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Molecular subtypes and the evolution of treatment management in metastatic colorectal cancer by Giulia Martini, Rodrigo Dienstmann, Javier Ros, Iosune Baraibar, Jose Luis Cuadra-Urteaga, Francesc Salva, Davide Ciardiello, Nuria Mulet, Guillem Argiles, Josep Tabernero, Elena Elez

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Mucosal Microbiota from Colorectal Cancer, Adenoma and Normal Epithelium Reveals the Imprint of <i>Fusobacterium nucleatum</i> in Cancerogenesis by Orazio Palmieri, Stefano Castellana, Anna Latiano, Tiziana Latiano, Annamaria Gentile, Anna Panza, Marianna Nardella, Davide Ciardiello, Tiziana Pia Latiano, Giuseppe Corritore, Tommaso Mazza, Francesco Perri, Giuseppe Biscaglia

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Correction: Ciardiello et al. Biomarker-Guided Anti-EGFR Rechallenge Therapy in Metastatic Colorectal Cancer. <i>Cancers</i> 2021, <i>13</i>, 1941 by Davide Ciardiello, Giulia Martini, Vincenzo Famiglietti, Stefania Napolitano, Vincenzo De Falco, Teresa Troiani, Tiziana Pia Latiano, Javier Ros, Elena Elez Fernandez, Pietro Paolo Vitiello, Evaristo Maiello, Fortunato Ciardiello, Erika Martinelli

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ITGB1 and DDR activation as novel mediators in acquired resistance to osimertinib and MEK inhibitors in EGFR-mutant NSCLC by Caterina De Rosa, Viviana De Rosa, Concetta Tuccillo, Virginia Tirino, Luisa Amato, Federica Papaccio, Davide Ciardiello, Stefania Napolitano, Giulia Martini, Fortunato Ciardiello, Floriana Morgillo, Francesca Iommelli, Carminia Maria Della Corte

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Biomarker-Guided Anti-EGFR Rechallenge Therapy in Metastatic Colorectal Cancer by Davide Ciardiello, Giulia Martini, Vincenzo Famiglietti, Stefania Napolitano, Vincenzo De Falco, Teresa Troiani, Tiziana Pia Latiano, Javier Ros, Elena Elez Fernandez, Pietro Paolo Vitiello, Evaristo Maiello, Fortunato Ciardiello, Erika Martinelli

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Immunotherapy for Biliary Tract Cancer in the Era of Precision Medicine: Current Knowledge and Future Perspectives by Davide Ciardiello, Brigida Anna Maiorano, Paola Parente, Maria Grazia Rodriquenz, Tiziana Pia Latiano, Cinzia Chiarazzo, Valerio Pazienza, Luigi Pio Guerrera, Brunella Amoruso, Nicola Normanno, Giulia Martini, Fortunato Ciardiello, Erika Martinelli, Evaristo Maiello

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