In vitro quantitative imaging assay for phagocytosis of dead neuroblastoma cells by iPSC-macrophages by Hall-Roberts, H, Di Daniel, E, James, WS, Davis, JB, Cowley, SA

A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6 by Priestley, RS, Cheung, J, Murphy, EJ, Ehebauer, MT, Davis, JB, Di Daniel, E

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation by Nizami, S, Millar, V, Arunasalam, K, Zarganes-Tzitzikas, T, Brough, D, Tresadern, G, Brennan, PE, Davis, JB, Ebner, D, Di Daniel, E

Structural premise of selective deubiquitinase USP30 inhibition by small-molecule benzosulfonamides by O'Brien, DP, Jones, HBL, Guenther, F, Murphy, EJ, England, KS, Anderson, M, Brennan, P, Davis, JB, Pinto-Fernandez, A, Turnbull, AP, Kessler, BM

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function by Carling, PJ, Ryan, BJ, McGuinness, W, Kataria, S, Humble, SW, Milde, S, Duce, JA, Kapadia, N, Zuercher, WJ, Davis, JB, Di Daniel, E, Wade-Martins, R

TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages by Hall-Roberts, H, Di Daniel, E, Agarwal, D, Obst, J, Smith, TB, Monzón-Sandoval, J, Webber, C, James, WS, Mead, E, Davis, JB, Cowley, SA

Structural premise of selective deubiquitinase USP30 inhibition by small-molecule benzosulfonamides by O’Brien, DP, Jones, HBL, Guenther, F, Murphy, EJ, England, KS, Vendrell, I, Anderson, M, Brennan, PE, Davis, JB, Pinto-Fernández, A, Turnbull, AP, Kessler, BM

Alzheimer’s disease drug discovery: targeting Dickkopf-1 induction of the Wnt-PCP non-canonical pathway by Johanssen, T, Wren, SP, Woffindale, C, Priestley, R, De Cesco, S, Ehebauer, MT, Dixon-Clarke, S, Katsouri, L, England, K, Bennet, JM, Fedorov, O, Brennan, PE, Di Daniel, E, Davis, JB

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain by Szykowska, A, Chen, Y, Smith, TB, Preger, C, Yang, J, Qian, D, Mukhopadhyay, SM, Wigren, E, Neame, SJ, Gräslund, S, Persson, H, Atkinson, PJ, Di Daniel, E, Mead, E, Wang, J, Davis, JB, Burgess-Brown, NA, Bullock, AN