Examining the roles of the pyruvate kinase isoforms, PKMI1 and PKM2, in systemic metabolism and tumor development by Dayton, Talya Lucia

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Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma by Dayton, Talya L., Miller, Kathryn M., Bronson, Roderick T., Dayton, Talya L., Gocheva, Vasilena, Miller, Kathryn, Bhutkar, Arjun, Chidley, Caroline, Vander Heiden, Matthew G., Jacks, Tyler E.

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Elevated circulating branched chain amino acids are an early event in pancreatic adenocarcinoma development by Mayers, Jared R., Torrence, Margaret E., Fiske, Brian Prescott, Davidson, Shawn Michael, Papagiannakopoulos, Thales, Dayton, Talya Lucia, Vander Heiden, Matthew G.

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PKM2 is not required for pancreatic ductal adenocarcinoma by Danai, Laura V, Di Vizio, Dolores, Hillis, Alissandra L., Lau, Allison N., Devoe, Camille X., Vander Heiden, Matthew G., Dayton, Talya Lucia

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PKM2 is not required for colon cancer initiated by APC loss by Sinnamon, Mark J, Georgeon, Larissa, Yilmaz, Omer H, Di Vizio, Dolores, Hung, Kenneth E, Vander Heiden, Matthew G, Lau, Allison N., Israelsen, William J., Sinnamon, Mark J., Dayton, Talya L., Hillis, Alissandra L., Hung, Kenneth E., Israelsen, William James, Roper, Jatin, Yilmaz, Omer, Vander Heiden, Matthew G., Dayton, Talya Lucia

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Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma by Chen, Guoan, Dayton, Talya Lucia, Kim-Kiselak, Caroline, Hoersch, Sebastian, Whittaker, Charles A., Bronson, Roderick T., Beer, David G., Winslow, Monte M., Li, Carman Man-Chung, Jacks, Tyler E

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Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma by Clish, Clary B., Bronson, Roderick T., Dayton, Talya L., Gocheva, Vasilena, Miller, Kathryn, Israelsen, William James, Bhutkar, Arjun, Davidson, Shawn Michael, Luengo, Alba, Jacks, Tyler E., Vander Heiden, Matthew G.

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Metabolic Pathway Alterations that Support Cell Proliferation by Vander Heiden, Matthew G., Lunt, Sophia Yunkyungkwon, Dayton, Talya Lucia, Fiske, Brian Prescott, Israelsen, William James, Mattaini, Katherine Ruth, Vokes, N. I., Stephanopoulos, G., Cantley, Lewis C., Metallo, Christian M., Locasale, Jason W.

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Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival by Gocheva, Vasilena, Naba, Alexandra, Bhutkar, Arjun, Guardia, Talia, Miller, Kathryn, Li, Carman Man Chung, Dayton, Talya L., Sanchez-Rivera, Francisco Javier, Kim-Kiselak, Caroline, Jailkhani, Noor, Winslow, Monte Meier, Del Rosario, Amanda M., Hynes, Richard O., Jacks, Tyler E.

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Nuclear Factor I/B is an Oncogene in Small Cell Lung Cancer by Dooley, Alison L., Winslow, Monte Meier, Chiang, Derek Y., Banerji, Shantanu, Stransky, Nicolas, Dayton, Talya Lucia, Snyder, Eric, Senna, Stephanie, Whittaker, Charles A., Bronson, Roderick T., Crowley, Denise G., Barretina, Jordi, Garraway, Levi A., Meyerson, Matthew L., Jacks, Tyler E

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Suppression of Lung Adenocarcinoma Progression by Nkx2-1 by Winslow, Monte Meier, Dayton, Talya Lucia, Kim-Kiselak, Caroline, Snyder, Eric, Feldser, David M., DuPage, Michel J., Whittaker, Charles A., Hoersch, Sebastian, Yoon, Stephanie M., Crowley, Denise G., Verhaak, Roel G., Hubbard, Diana D., Chiang, Derek Y., Myerson, Matthew, Bronson, Roderick T., Jacks, Tyler E

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p53 Controls Radiation-Induced Gastrointestinal Syndrome in Mice Independent of Apoptosis by Kirsch, David G., Santiago, Philip M., di Tomaso, Emmanuelle, Sullivan, Julie M., Hou, Wu-Shiun, Dayton, Talya Lucia, Jeffords, Laura B., Sodha, Pooja, Mercer, Kim L., Cohen, Rhianna, Takeuchi, Osamu, Korsmeyer, Stanley J., Bronson, Roderick T., Kim, Carla F., Haigis, Kevin M., Jain, Rakesh K., Jacks, Tyler E

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Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing by Taylor-Weiner, Amaro, Stewart, Chip, Carter, Scott L., Cibulskis, Kristian, McKenna, Aaron, Dooley, Alison, Sougnez, Carrie, Park, Jennifer, Farago, Anna F., Dayton, Talya, Shefler, Erica, Gabriel, Stacey, Getz, Gad, McFadden, David Glenn, Papagiannakopoulos, Thales, Bhutkar, Arjun, Vernon, Amanda, Malstrom, Scott E., Heimann, Megan Kristianne, Parker, Jennifer E., Chen, Frances K., Jacks, Tyler E.

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PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells by Li, Jie, Sasaki, Mika, Horner, James W., Burga, Laura N., Xie, Jianxin, Jurczak, Michael J., DePinho, Ronald A., Clish, Clary B., Kibbey, Richard G., Wulf, Gerburg M., Di Vizio, Dolores, Mills, Gordon B., Cantley, Lewis C., Israelsen, William James, Dayton, Talya L., Davidson, Shawn M., Fiske, Brian Prescott, Hosios, Aaron Marc, Bellinger, Gary, Yu, Yimin, Jacks, Tyler E., Vander Heiden, Matthew G.

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Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma by Davidson, Shawn M, Schmidt, Daniel R, Heyman, Julia E, O'Brien, James P, Liu, Amy C, Israelsen, William J, Dayton, Talya L, Sehgal, Raghav, Bronson, Roderick T, Freinkman, Elizaveta, Mak, Howard H, Fanelli, Giuseppe Nicolò, Malstrom, Scott, Bellinger, Gary, Carracedo, Arkaitz, Pandolfi, Pier Paolo, Courtney, Kevin D, Jha, Abhishek, DePinho, Ronald A, Horner, James W, Thomas, Craig J, Cantley, Lewis C, Loda, Massimo, Vander Heiden, Matthew G

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Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation by Lunt, Sophia Y., Muralidhar, Vinayak, Israelsen, William J., Newhouse, Lauren, Ogrodzinski, Martin, Xu, Kali, Hollern, Daniel P., Bellinger, Gary, Christen, Stefan, Elia, Ilaria, Dinh, Anh T., Stephanopoulos, Gregory, Manalis, Scott R., Yaffe, Michael B., Andrechek, Eran R., Fendt, Sarah-Maria, Vander Heiden, Matthew G., Hosios, Aaron Marc, Gui, Dan Yi, Acevedo, Paula N. Marin, Dayton, Talya Lucia, Lunt, Sophia Y., Dinh, Anh T., Vander Heiden, Matthew G., Manalis, Scott R, Yaffe, Michael B, Hecht, Vivian Chaya

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