The role of DNA-demethylating agents in cancer therapy by Mehdipour, P, Murphy, T, De Carvalho, DD

The next generation of DNMT inhibitors by Mehdipour, P, Chen, R, De Carvalho, DD

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer by Hosseini, A, Lindholm, HT, Chen, R, Mehdipour, P, Marhon, SA, Ishak, CA, Moore, PC, Classon, M, Di Gioacchino, A, Greenbaum, B, De Carvalho, DD

Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency by Mehdipour, P, Marhon, SA, Ettayebi, I, Chakravarthy, A, Hosseini, A, Wang, Y, de Castro, FA, Loo Yau, H, Ishak, C, Abelson, S, O’Brien, CA, De Carvalho, DD

LSD1 ablation stimulates anti-tumor immunity and enables checkpoint blockade by Sheng, W, LaFleur, MW, Nguyen, TH, Chen, S, Chakravarthy, A, Conway, JR, Li, Y, Chen, H, Yang, H, Hsu, P-H, Van Allen, EM, Freeman, GJ, De Carvalho, DD, He, HH, Sharpe, AH, Shi, Y

Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia by de Castro, FA, Mehdipour, P, Chakravarthy, A, Ettayebi, I, Loo Yau, H, Medina, TS, Marhon, SA, de Almeida, FC, Bianco, TM, Arruda, AGF, Devlin, R, de Figueiredo‐Pontes, LL, Chahud, F, da Costa Cacemiro, M, Minden, MD, Gupta, V, De Carvalho, DD

Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways by Feng, S, Marhon, SA, Sokolowski, DJ, D’Costa, A, Soares, F, Mehdipour, P, Ishak, C, Loo Yau, H, Ettayebi, I, Patel, PS, Chen, R, Liu, J, Zuzarte, PC, Ho, KC, Ho, B, Ning, S, Huang, A, Arrowsmith, CH, Wilson, MD, Simpson, JT, De Carvalho, DD

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma by Nikolic, A, Maule, F, Bobyn, A, Ellestad, K, Paik, S, Marhon, SA, Mehdipour, P, Lun, X, Chen, H-M, Mallard, C, Hay, AJ, Johnston, MJ, Gafuik, CJ, Zemp, FJ, Shen, Y, Ninkovic, N, Osz, K, Labit, E, Berger, ND, Brownsey, DK, Kelly, JJ, Biernaskie, J, Dirks, PB, Derksen, DJ, Jones, SJM, Senger, DL, Chan, JA, Mahoney, DJ, De Carvalho, DD, Gallo, M

PRMT inhibition induces a viral mimicry response in triple-negative breast cancer by Wu, Q, Nie, DY, Ba-Alawi, W, Ji, Y, Zhang, Z, Cruickshank, J, Haight, J, Ciamponi, FE, Chen, J, Duan, S, Shen, Y, Liu, J, Marhon, SA, Mehdipour, P, Szewczyk, MM, Dogan-Artun, N, Chen, W, Zhang, LX, Deblois, G, Prinos, P, Massirer, KB, Barsyte-Lovejoy, D, Jin, J, De Carvalho, DD, Haibe-Kains, B, Wang, X, Cescon, DW, Lupien, M, Arrowsmith, CH