A comparison of the efficacy and safety of oral and intravenous fludarabine in chronic lymphocytic leukemia in the LRF CLL4 trial. by Dearden, C, Richards, S, Else, M, Catovsky, D, Hillmen, P

Fludarabine plus cyclophosphamide induces better response rates and progression-free survival across all age and risk groups in the LRF CLL4 trial (on behalf of the UKNCRI CLL Tria... by Catovsky, D, Richards, S, Dearden, C, Matutes, E, Dyer, M, Hillmen, P

The combination of fludarabine and cyclophosphamide has a beneficial effect on the incidence of hemolytic anemia in chronic lymphocytic leukemia. Results from the UK LRF CLL4 trial by Dearden, C, Wade, R, Else, M, Richards, S, Milligan, D, Hamblin, T, Catovsky, D

The prognostic significance of a positive direct antiglobulin test in chronic lymphocytic leukemia: a beneficial effect of the combination of fludarabine and cyclophosphamide on th... by Dearden, C, Wade, R, Else, M, Richards, S, Milligan, D, Hamblin, T, Catovsky, D

Response to therapy and survival in CLL is influenced by genetic markers. preliminary analysis from the LRF CLL4 trial. by Catovsky, D, Richards, S, Matutes, E, Burford, A, Brito-Babapulle, V, Dearden, C, Morris, P, Pettitt, A

Mutational status of the TP53 gene as a predictor of response and survival in patients with chronic lymphocytic leukemia: results from the LRF CLL4 trial. by Gonzalez, D, Martinez, P, Wade, R, Hockley, S, Oscier, D, Matutes, E, Dearden, C, Richards, S, Catovsky, D, Morgan, G

Drug cross-resistance and therapy-induced resistance in chronic lymphocytic leukaemia by an enhanced method of individualised tumour response testing. by Bosanquet, A, Richards, S, Wade, R, Else, M, Matutes, E, Dyer, M, Rassam, S, Durant, J, Scadding, S, Raper, S, Dearden, C, Catovsky, D

Mutational Status of the TP53 Gene as a Predictor of Response and Survival in CLL Patients with and without 17p Deletion by Gonzalez, D, Martinez, P, Wade, R, Hockley, S, Brito-Babapulle, V, Oscier, D, Matutes, E, Dearden, C, Richards, S, Catovsky, D, Morgan, G

Guidelines on the diagnosis, investigation and management of chronic lymphocytic leukaemia. by Oscier, D, Dearden, C, Eren, E, Erem, E, Fegan, C, Follows, G, Hillmen, P, Illidge, T, Matutes, E, Milligan, D, Pettitt, A, Schuh, A, Wimperis, J

Functional analysis of the ATM-p53-p21 pathway in the LRF CLL4 trial: blockade at the level of p21 is associated with short response duration. by Lin, K, Adamson, J, Johnson, G, Carter, A, Oates, M, Wade, R, Richards, S, Gonzalez, D, Matutes, E, Dearden, C, Oscier, D, Catovsky, D, Pettitt, A

AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION (AUTOHSCT) IN CLL: FIRST RESULTS OF AN EBMT RANDOMIZED TRIAL COMPARING AUTOTRANSPLANT VERSUS WAIT AND WATCH by Michallet, M, Dreger, P, Sutton, L, Brand, R, Richards, S, van Biezen, A, Sobh, M, Gratwohl, M, Kolbe, K, Dearden, C, Hallek, M, de Witte, T, Niederweiser, D, Leporrier, M, Milligan, D

Autologous Hematopoietic Stem Cell Transplantation (autoHSCT) in CLL: First Results of An EBMT Randomized Trial Comparing Autotransplant Versus Wait and Watch by Michallet, M, Dreger, P, Sutton, L, Brand, R, Richards, S, van Biezen, A, Sobh, M, Gratwohl, A, Kolbe, K, Dearden, C, Hallek, M, de Witte, T, Niederwieser, D, Leporrier, M, Milligan, D

Autologous haematopoietic stem cell transplantation in CLL: first results of an EBMT randomized trial comparing autotransplant versus wait and watch by Michallet, M, Dreger, P, Sutton, L, Brand, R, Richards, S, Van Biezen, A, Sobh, M, Gratwohl, A, Kolbe, K, Dearden, C, Hallek, M, De Witte, T, Niederwieser, D, Leporrier, M, Milligan, D

Final results of a randomized trial comparing autotransplant versus wait and watch in 222 patients with CLL in 1(st) or 2(nd) remission (EBMT CLL auto trial / GCLLSG CLL3R trial) by McClanahan, F, Michallet, M, Milligan, D, Sutton, L, Brand, R, Richards, S, Van Biezen, A, Sobh, M, Gratwohl, A, Herr, W, Dearden, C, Hallek, M, Stilgenbauer, S, De Witte, T, Niederwieser, D, Leporrier, M, Dreger, P

Autologous hematopoietic stem cell transplantation in chronic lymphocytic leukemia: results of European intergroup randomized trial comparing autografting versus observation. by Michallet, M, Dreger, P, Sutton, L, Brand, R, Richards, S, van Os, M, Sobh, M, Choquet, S, Corront, B, Dearden, C, Gratwohl, A, Herr, W, Catovsky, D, Hallek, M, de Witte, T, Niederwieser, D, Leporrier, M, Milligan, D

Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial. by Catovsky, D, Richards, S, Matutes, E, Oscier, D, Dyer, M, Bezares, R, Pettitt, A, Hamblin, T, Milligan, D, Child, J, Hamilton, MS, Dearden, C, Smith, A, Bosanquet, A, Davis, Z, Brito-Babapulle, V, Else, M, Wade, R, Hillmen, P

Alemtuzumab in combination with methylprednisolone is a highly effective induction regimen for patients with chronic lymphocytic leukemia and deletion of TP53: final results of the... by Pettitt, A, Jackson, R, Carruthers, S, Dodd, J, Dodd, S, Oates, M, Johnson, G, Schuh, A, Matutes, E, Dearden, C, Catovsky, D, Radford, J, Bloor, A, Follows, G, Devereux, S, Kruger, A, Blundell, J, Agrawal, S, Allsup, D, Proctor, S, Heartin, E, Oscier, D, Hamblin, T, Rawstron, A, Hillmen, P

The HadGEM2 family of Met Office Unified Model climate configurations by Martin, G, Bellouin, N, Collins, W, Culverwell, I, Halloran, P, Hardiman, S, Hinton, T, Jones, C, McDonald, R, McLaren, A, O'Connor, F, Roberts, M, Rodriguez, J, Woodward, S, Best, M, Brooks, M, Brown, A, Butchart, N, Dearden, C, Derbyshire, S, Dharssi, I, Doutriaux-Boucher, M, Edwards, J, Falloon, P, Gedney, N