Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study by Liu, J, Semiz, S, Van Der Lee, S, Van Der Spek, A, Verhoeven, A, Van Klinken, J, Sijbrands, E, Harms, A, Hankemeier, T, Van Dijk, K, Van Duijn, C, Demirkan, A

A combined linkage and exome sequencing analysis for electrocardiogram parameters in the erasmus rucphen family study by Silva, C, Zorkoltseva, I, Amin, N, Demirkan, A, Van Leeuwen, E, Kors, J, Van Den Berg, M, Stricker, B, Uitterlinden, A, Kirichenko, A, Witteman, J, Willemsen, R, Oostra, B, Axenovich, T, Van Duijn, C, Isaacs, A

A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy by Silva, C, Zorkoltseva, I, Niemeijer, M, Van Den Berg, M, Amin, N, Demirkan, A, Van Leeuwen, E, Iglesias, A, Piñeros-Hernández, L, Restrepo, C, Kors, J, Kirichenko, A, Willemsen, R, Oostra, B, Stricker, B, Uitterlinden, A, Axenovich, T, Van Duijn, C, Isaacs, A

Lipidomic profiling identifies signatures of metabolic risk by Yin, X, Willinger, CM, Keefe, J, Liu, J, Fernández-Ortiz, A, Ibáñez, B, Peñalvo, J, Adourian, A, Chen, G, Corella, D, Pamplona, R, Portero-Otin, M, Jove, M, Courchesne, P, Van Duijn, CM, Fuster, V, Ordovás, JM, Demirkan, A, Larson, MG, Levy, D

CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers by Ahmad, S, del Campo Milan, M, Hansson, O, Demirkan, A, Agustin, R, Sáez, ME, Giagtzoglou, N, Cabrera-Socorro, A, Bakker, MHM, Ramirez, A, Hankemeier, T, Stomrud, E, Mattsson-Carlgren, N, Scheltens, P, van der Flier, WM, Ikram, MA, Malarstig, A, Teunissen, CE, Amin, N, van Duijn, CM

Common variants associated with plasma triglycerides and risk for coronary artery disease. by Do, R, Willer, C, Schmidt, E, Sengupta, S, Gao, C, Peloso, G, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M, Mora, S, Beckmann, J, Bragg-Gresham, J, Chang, H, Demirkan, A, Den Hertog, H, Donnelly, L, Ehret, G, Esko, T, Feitosa, M, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R

Discovery and refinement of loci associated with lipid levels. by Willer, C, Schmidt, E, Sengupta, S, Peloso, G, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M, Mora, S, Beckmann, J, Bragg-Gresham, J, Chang, H, Demirkan, A, Den Hertog, H, Do, R, Donnelly, L, Ehret, G, Esko, T, Feitosa, M, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R, Freitag, D

Common variants associated with plasma triglycerides and risk for coronary artery disease by Do, R, Willer, C, Schmidt, E, Sengupta, S, Gao, C, Peloso, G, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M, Mora, S, Beckmann, J, Bragg-Gresham, J, Chang, H, Demirkan, A, Den Hertog, H, Donnelly, L, Ehret, G, Esko, T, Feitosa, M, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R

Genetic architecture of circulating lipid levels. by Demirkan, A, Amin, N, Isaacs, A, Jarvelin, MR, Whitfield, J, Wichmann, H, Kyvik, K, Rudan, I, Gieger, C, Hicks, A, Johansson, Å, Hottenga, J, Smith, J, Wild, S, Pedersen, N, Willemsen, G, Mangino, M, Hayward, C, Uitterlinden, A, Hofman, A, Witteman, J, Montgomery, G, Pietiläinen, K, Rantanen, T, Kaprio, J

Genetic architecture of circulating lipid levels by Demirkan, A, Amin, N, Isaacs, A, Jarvelin, M, Whitfield, J, Wichmann, H, Kyvik, K, Rudan, I, Gieger, C, Hicks, A, Johansson, A, Hottenga, J, Smith, J, Wild, S, Pedersen, N, Willemsen, G, Mangino, M, Hayward, C, Uitterlinden, A, Hofman, A, Witteman, J, Montgomery, G, Pietiläinen, K, Rantanen, T, Kaprio, J

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: The ENGAGE consortium by Van Der Spek, A, Broer, L, Draisma, HHM, Pool, R, Albrecht, E, Beekman, M, Mangino, M, Raag, M, Nyholt, DR, Dharuri, HK, Codd, V, Amin, N, De Geus, EJC, Deelen, J, Demirkan, A, Yet, I, Fischer, K, Haller, T, Henders, AK, Isaacs, A, Medland, SE, Montgomery, GW, Mooijaart, SP, Strauch, K, Suchiman, HED

Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels by Tin, A, Li, Y, Brody, J, Nutile, T, Chu, A, Huffman, J, Yang, Q, Chen, M, Robinson-Cohen, C, Macé, A, Liu, J, Demirkan, A, Sorice, R, Sedaghat, S, Swen, M, Yu, B, Ghasemi, S, Teumer, A, Vollenweider, P, Ciullo, M, Li, M, Uitterlinden, A, Kraaij, R, Amin, N, Van Rooij, J, Kutalik, Z, Dehghan, A, McKnight, B, Van Duijn, C, Morrison, A, Psaty, B, Boerwinkle, E, Fox, C, Woodward, O, Köttgen, A

Increased high-density lipoprotein levels associated with age-related macular degeneration: evidence from the EYE-RISK and European Eye Epidemiology Consortia by Colijn, JM, Hollander, AI, Demirkan, A, Cougnard-Grégoire, A, Verzijden, T, Kersten, E, Meester-Smoor, MA, Merle, BMJ, Papageorgiou, G, Ahmad, S, Mulder, MT, Costa, MA, Benlian, P, Bertelsen, G, Bron, AM, Claes, B, Creuzot-Garcher, C, Erke, MG, Fauser, S, Foster, PJ, Hammond, CJ, Hense, H-W, Hoyng, CB, Khawaja, AP, Korobelnik, J-F, Piermarocchi, S, Segato, T, Silva, R, Souied, EH, Williams, KM, Van Duijn, CM, Delcourt, C, Klaver, CCW, European Eye Epidemiology Consortium, Eye-Risk Consortium

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine by Onderwater, GLJ, Ligthart, L, Bot, M, Demirkan, A, Fu, J, Van Der Kallen, CJH, Vijfhuizen, LS, Pool, R, Liu, J, Vanmolkot, FHM, Beekman, M, Wen, K-X, Amin, N, Thesing, CS, Pijpers, JA, Kies, DA, Zielman, R, De Boer, I, Van Greevenbroek, MMJ, Arts, ICW, Milaneschi, Y, Schram, MT, Dagnelie, PC, Franke, L, Ikram, MA, Ferrari, MD, Goeman, JJ, Slagboom, PE, Wijmenga, C, Stehouwer, CDA, Boomsma, DI, Van Duijn, CM, Penninx, BW, Hoen, PAC, Terwindt, GM, Van Den Maagdenberg, AMJM, Bbmri Metabolomics Consortium

Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose by Wu, P, Rybin, D, Bielak, LF, Feitosa, MF, Franceschini, N, Li, Y, Lu, Y, Marten, J, Musani, SK, Noordam, R, Raghavan, S, Rose, LM, Schwander, K, Smith, AV, Tajuddin, SM, Vojinovic, D, Amin, N, Arnett, DK, Bottinger, EP, Demirkan, A, Florez, JC, Ghanbari, M, Harris, TB, Launer, LJ, Liu, J, Liu, J, Mook-Kanamori, DO, Murray, AD, Nalls, MA, Peyser, PA, Uitterlinden, AG, Voortman, T, Bouchard, C, Chasman, D, Correa, A, de Mutsert, R, Evans, MK, Gudnason, V, Hayward, C, Kao, L, Kardia, SLR, Kooperberg, C, Loos, RJF, Province, MM, Rankinen, T, Redline, S, Ridker, PM, Rotter, JI, Siscovick, D, Smith, BH, van Duijn, C

Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity by Yaghootkar, H, Zhang, Y, Spracklen, CN, Karaderi, T, Huang, LO, Bradfield, J, Schurmann, C, Fine, RS, Preuss, MH, Kutalik, Z, Wittemans, LB, Lu, Y, Metz, S, Willems, SM, Li-Gao, R, Grarup, N, Wang, S, Molnos, S, Sandoval-Zárate, AA, Nalls, MA, Lange, LA, Haesser, J, Guo, X, Lyytikäinen, L-P, Feitosa, MF, Sitlani, CM, Venturini, C, Mahajan, A, Kacprowski, T, Wang, CA, Chasman, DI, Amin, N, Broer, L, Robertson, N, Young, KL, Allison, M, Auer, PL, Blüher, M, Borja, JB, Bork-Jensen, J, Carrasquilla, GD, Christofidou, P, Demirkan, A, Doege, CA, Garcia, ME, Graff, M, Guo, K, Hakonarson, H, Hong, J, Ida Chen, Y-D, van Duijn, CM, Et al.

Genome-wide characterization of circulating metabolic biomarkers by Karjalainen, MK, Karthikeyan, S, Oliver-Williams, C, Sliz, E, Allara, E, Fung, WT, Surendran, P, Zhang, W, Jousilahti, P, Kristiansson, K, Salomaa, V, Goodwin, M, Hughes, DA, Boehnke, M, Fernandes Silva, L, Yin, X, Mahajan, A, Neville, MJ, van Zuydam, NR, de Mutsert, R, Li-Gao, R, Mook-Kanamori, DO, Demirkan, A, Liu, J, Noordam, R, Trompet, S, Chen, Z, Kartsonaki, C, Li, L, Lin, K, Hagenbeek, FA, Hottenga, JJ, Pool, R, Ikram, MA, van Meurs, J, Haller, T, Milaneschi, Y, Kähönen, M, Mishra, PP, Joshi, PK, Macdonald-Dunlop, E, Mangino, M, Zierer, J, Acar, IE, Hoyng, CB, Lechanteur, YTE, Franke, L, Kurilshikov, A, Zhernakova, A, Beekman, M, Walters, RG, Karpe, F, McCarthy, MI, van Duijn, C, Kettunen, J

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas by Liu, J, Lahousse, L, Nivard, MG, Bot, M, Chen, L, van Klinken, JB, Thesing, CS, Beekman, M, van den Akker, EB, Slieker, RC, Waterham, E, van der Kallen, CJH, de Boer, I, Li-Gao, R, Vojinovic, D, Amin, N, Radjabzadeh, D, Kraaij, R, Alferink, LJM, Murad, SD, Uitterlinden, AG, Willemsen, G, Pool, R, Milaneschi, Y, van Heemst, D, Suchiman, HED, Rutters, F, Elders, PJM, Beulens, JWJ, van der Heijden, AAWA, van Greevenbroek, MJM, Arts, ICW, Onderwater, GLJ, van den Maagdenberg, AMJM, Mook-Kanamori, DO, Hankemeier, T, Terwindt, GM, Stehouwer, CDA, Geleijnse, JM, Hart, LMT, Slagboom, PE, van Dijk, KW, Zhernakova, A, Fu, J, Penninx, BWJH, Boomsma, DI, Demirkan, A, Stricker, BHC, van Duijn, CM

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis by Liu, J, Carnero-Montoro, E, Van Dongen, J, Lent, S, Nedeljkovic, I, Ligthart, S, Tsai, P, Martin, T, Mandaviya, P, Jansen, R, Peters, M, Duijts, L, Jaddoe, V, Tiemeier, H, Felix, J, Willemsen, G, De Geus, E, Chu, A, Levy, D, Hwang, S, Bressler, J, Gondalia, R, Salfati, E, Herder, C, Hidalgo, B, Tanaka, T, Moore, A, Lemaitre, R, Jhun, M, Smith, J, Sotoodehnia, N, Bandinelli, S, Ferrucci, L, Arnett, D, Grallert, H, Assimes, T, Hou, L, Baccarelli, A, Whitsel, E, Van Dijk, K, Amin, N, Uitterlinden, A, Sijbrands, E, Franco, O, Dehghan, A, Spector, T, Dupuis, J, Hivert, M, Rotter, J, Meigs, J, Pankow, J, Van Meurs, J, Isaacs, A, Boomsma, D, Bell, J, Demirkan, A, Van Duijn, C

Exome-derived adiponectin-associated variants implicate obesity and lipid biology by Spracklen, CN, Karaderi, T, Yaghootkar, H, Schurmann, C, Fine, RS, Kutalik, Z, Preuss, MH, Lu, Y, Wittemans, LBL, Adair, LS, Allison, M, Amin, N, Auer, PL, Bartz, TM, Blüher, M, Boehnke, M, Borja, JB, Bork-Jensen, J, Broer, L, Chasman, DI, Chen, Y-DI, Chirstofidou, P, Demirkan, A, Van Duijn, CM, Feitosa, MF, Garcia, ME, Graff, M, Grallert, H, Grarup, N, Guo, X, Haesser, J, Hansen, T, Harris, TB, Highland, HM, Hong, J, Ikram, MA, Ingelsson, E, Jackson, R, Jousilahti, P, Kähönen, M, Kizer, JR, Kovacs, P, Kriebel, J, Laakso, M, Lange, LA, Lehtimäki, T, Li, J, Li-Gao, R, Lind, L, Luan, J, Lyytikäinen, L-P, Macgregor, S, Mackey, DA, Mahajan, A, Mangino, M, Männistö, S, McCarthy, MI, McKnight, B, Medina-Gomez, C, Meigs, JB, Molnos, S, Mook-Kanamori, D, Morris, AP, De Mutsert, R, Nalls, MA, Nedeljkovic, I, North, KE, Pennell, CE, Pradhan, AD, Province, MA, Raitakari, OT, Raulerson, CK, Reiner, AP, Ridker, PM, Ripatti, S, Roberston, N, Rotter, JI, Salomaa, V, Sandoval-Zárate, AA, Sitlani, CM, Spector, TD, Strauch, K, Stumvoll, M, Taylor, KD, Thuesen, B, Tönjes, A, Uitterlinden, AG, Venturini, C, Walker, M, Wang, CA, Wang, S, Wareham, NJ, Willems, SM, Van Dijk, K, Wilson, JG, Wu, Y, Yao, J, Young, KL, Langenberg, C, Frayling, TM, Kilpeläinen, TO, Lindgren, CM, Loos, RJF, Mohlke, KL