Denis Duboule

Denis Duboule in 2010 Denis Duboule (born February 17, 1955) is a Swiss-French biologist. He earned his PhD in Biology in 1984 and is currently Professor of Developmental Genetics and Genomics at the École polytechnique fédérale de Lausanne (EPFL) and at the Department of Genetics and Evolution of the University of Geneva. Since 2001, he is the Director of the Swiss National Research Center "Frontiers in Genetics" and since 2017, he is also a professor at the Collège de France. He has notably worked on Hox genes, a group of genes involved in the formation of the body plan and of the limbs. Provided by Wikipedia
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  1. 1
    Structural and functional differences in the long non-coding RNA hotair in mouse and human.

    Structural and functional differences in the long non-coding RNA hotair in mouse and human. by Patrick Schorderet, Denis Duboule

    Published 2011-05-01
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  2. 2
    Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo

    Rescue of an aggressive female sexual courtship in mice by CRISPR/Cas9 secondary mutation in vivo by Jozsef Zakany, Denis Duboule

    Published 2018-03-01
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  3. 3
    Distinct roles and regulations for HoxD genes in metanephric kidney development.

    Distinct roles and regulations for HoxD genes in metanephric kidney development. by Nicolas Di-Poï, József Zákány, Denis Duboule

    Published 2007-12-01
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  4. 4
    Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits.

    Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits. by Joost M Woltering, Daan Noordermeer, Marion Leleu, Denis Duboule

    Published 2014-01-01
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  5. 5
    Uncoupling time and space in the collinear regulation of Hox genes.

    Uncoupling time and space in the collinear regulation of Hox genes. by Patrick Tschopp, Basile Tarchini, François Spitz, Jozsef Zakany, Denis Duboule

    Published 2009-03-01
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  6. 6
    Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

    Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations by Christopher Chase Bolt, Lucille Lopez-Delisle, Bénédicte Mascrez, Denis Duboule

    Published 2021-08-01
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  7. 7
    Hotair Is Dispensible for Mouse Development.

    Hotair Is Dispensible for Mouse Development. by Ana Rita Amândio, Anamaria Necsulea, Elisabeth Joye, Bénédicte Mascrez, Denis Duboule

    Published 2016-12-01
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  8. 8
    Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci

    Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci by Daan Noordermeer, Marion Leleu, Patrick Schorderet, Elisabeth Joye, Fabienne Chabaud, Denis Duboule

    Published 2014-04-01
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  9. 9
    A complex regulatory landscape involved in the development of mammalian external genitals

    A complex regulatory landscape involved in the development of mammalian external genitals by Ana Rita Amândio, Lucille Lopez-Delisle, Christopher Chase Bolt, Bénédicte Mascrez, Denis Duboule

    Published 2020-04-01
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  10. 10
    Multiple Enhancers Regulate Hoxd Genes and the Hotdog LncRNA during Cecum Budding

    Multiple Enhancers Regulate Hoxd Genes and the Hotdog LncRNA during Cecum Budding by Saskia Delpretti, Thomas Montavon, Marion Leleu, Elisabeth Joye, Athanasia Tzika, Michel Milinkovitch, Denis Duboule

    Published 2013-10-01
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  11. 11
    A genetic approach to the recruitment of PRC2 at the HoxD locus.

    A genetic approach to the recruitment of PRC2 at the HoxD locus. by Patrick Schorderet, Nicolas Lonfat, Fabrice Darbellay, Patrick Tschopp, Sandra Gitto, Natalia Soshnikova, Denis Duboule

    Published 2013-11-01
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  12. 12
    Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

    Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes by Eddie Rodríguez-Carballo, Lucille Lopez-Delisle, Nayuta Yakushiji-Kaminatsui, Asier Ullate-Agote, Denis Duboule

    Published 2019-07-01
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  13. 13
    Induction of a chromatin boundary in vivo upon insertion of a TAD border.

    Induction of a chromatin boundary in vivo upon insertion of a TAD border. by Andréa Willemin, Lucille Lopez-Delisle, Christopher Chase Bolt, Marie-Laure Gadolini, Denis Duboule, Eddie Rodriguez-Carballo

    Published 2021-07-01
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  14. 14
    Context-dependent enhancer function revealed by targeted inter-TAD relocation

    Context-dependent enhancer function revealed by targeted inter-TAD relocation by Christopher Chase Bolt, Lucille Lopez-Delisle, Aurélie Hintermann, Bénédicte Mascrez, Antonella Rauseo, Guillaume Andrey, Denis Duboule

    Published 2022-06-01
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  15. 15
    Large scale genomic reorganization of topological domains at the HoxD locus

    Large scale genomic reorganization of topological domains at the HoxD locus by Pierre J. Fabre, Marion Leleu, Benjamin H. Mormann, Lucille Lopez-Delisle, Daan Noordermeer, Leonardo Beccari, Denis Duboule

    Published 2017-08-01
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  16. 16
    Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan

    Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan by Isabel Guerreiro, Sandra Gitto, Ana Novoa, Julien Codourey, Thi Hanh Nguyen Huynh, Federico Gonzalez, Michel C Milinkovitch, Moises Mallo, Denis Duboule

    Published 2016-08-01
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  17. 17
    A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus.

    A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus. by Marc Friedli, Isabelle Barde, Mélanie Arcangeli, Sonia Verp, Alexandra Quazzola, Jozsef Zakany, Nathalie Lin-Marq, Daniel Robyr, Catia Attanasio, François Spitz, Denis Duboule, Didier Trono, Stylianos E Antonarakis

    Published 2010-01-01
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  18. 18
    Considerations when investigating lncRNA function in vivo

    Considerations when investigating lncRNA function in vivo by Andrew R Bassett, Asifa Akhtar, Denise P Barlow, Adrian P Bird, Neil Brockdorff, Denis Duboule, Anne Ephrussi, Anne C Ferguson-Smith, Thomas R Gingeras, Wilfried Haerty, Douglas R Higgs, Eric A Miska, Chris P Ponting

    Published 2014-08-01
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