Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging by Francesco Longo, Isabella Russo, Derya R. Shimshek, Elisa Greggio, Michele Morari

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Surfactant secretion in LRRK2 knock-out rats: changes in lamellar body morphology and rate of exocytosis. by Pika Miklavc, Konstantin Ehinger, Kristin E Thompson, Nina Hobi, Derya R Shimshek, Manfred Frick

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G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice by Salvatore Novello, Ludovico Arcuri, Sandra Dovero, Nathalie Dutheil, Derya R. Shimshek, Erwan Bezard, Michele Morari

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Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo by Federica Albanese, Daniela Mercatelli, Luca Finetti, Giulia Lamonaca, Sara Pizzi, Derya R. Shimshek, Giovanni Bernacchia, Michele Morari

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Enhanced odor discrimination and impaired olfactory memory by spatially controlled switch of AMPA receptors. by Derya R Shimshek, Thorsten Bus, Jinhyun Kim, Andre Mihaljevic, Volker Mack, Peter H Seeburg, Rolf Sprengel, Andreas T Schaefer

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Imaging of Cerebrovascular Pathology in Animal Models of Alzheimer`s Disease by Jan eKlohs, Jan eKlohs, Markus eRudin, Markus eRudin, Markus eRudin, Derya R. Shimshek, Nicolau eBeckmann

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Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice. by Douglas Young, Franziska Mayer, Nella Vidotto, Tatjana Schweizer, Ramon Berth, Dorothee Abramowski, Derya R Shimshek, P Herman van der Putten, Peter Schmid

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Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model by Nicolau Beckmann, Anna Neuhaus, Stefan Zurbruegg, Pia Volkmer, Claudia Patino, Stefanie Joller, Dominik Feuerbach, Arno Doelemeyer, Tatjana Schweizer, Stefan Rudin, Ulf Neumann, Ramon Berth, Wilfried Frieauff, Fabrizio Gasparini, Derya R. Shimshek

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High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain. by Martin C Herzig, Michael Bidinosti, Tatjana Schweizer, Thomas Hafner, Christine Stemmelen, Andreas Weiss, Simone Danner, Nella Vidotto, Daniela Stauffer, Carmen Barske, Franziska Mayer, Peter Schmid, Giorgio Rovelli, P Herman van der Putten, Derya R Shimshek

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Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions by Gaye Tanriöver, Mehtap Bacioglu, Manuel Schweighauser, Jasmin Mahler, Bettina M. Wegenast-Braun, Angelos Skodras, Ulrike Obermüller, Melanie Barth, Deborah Kronenberg-Versteeg, K. Peter R. Nilsson, Derya R. Shimshek, Philipp J. Kahle, Yvonne S. Eisele, Mathias Jucker

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Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units by Elisa Giorgetti, Moh Panesar, Yunyu Zhang, Stefanie Joller, Marie Ronco, Michael Obrecht, Christian Lambert, Nathalie Accart, Nicolau Beckmann, Arno Doelemeyer, Ludovic Perrot, Isabelle Fruh, Matthias Mueller, Eliane Pierrel, Serge Summermatter, Michael Bidinosti, Derya R. Shimshek, Sophie Brachat, Mark Nash

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Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon aging. by David Marcellin, Dorothee Abramowski, Douglas Young, Jens Richter, Andreas Weiss, Audrey Marcel, Julia Maassen, Muriel Kauffmann, Miriam Bibel, Derya R Shimshek, Richard L M Faull, Gillian P Bates, Rainer R Kuhn, P Herman Van der Putten, Peter Schmid, Gregor P Lotz

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Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures by Melanie Barth, Mehtap Bacioglu, Niklas Schwarz, Renata Novotny, Janine Brandes, Marc Welzer, Sonia Mazzitelli, Lisa M. Häsler, Manuel Schweighauser, Thomas V. Wuttke, Deborah Kronenberg-Versteeg, Karina Fog, Malene Ambjørn, Ania Alik, Ronald Melki, Philipp J. Kahle, Derya R. Shimshek, Henner Koch, Mathias Jucker, Gaye Tanriöver

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The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease by Ulf Neumann, Mike Ufer, Laura H Jacobson, Marie‐Laure Rouzade‐Dominguez, Gunilla Huledal, Carine Kolly, Rainer M Lüönd, Rainer Machauer, Siem J Veenstra, Konstanze Hurth, Heinrich Rueeger, Marina Tintelnot‐Blomley, Matthias Staufenbiel, Derya R Shimshek, Ludovic Perrot, Wilfried Frieauff, Valerie Dubost, Hilmar Schiller, Barbara Vogg, Karen Beltz, Alexandre Avrameas, Sandrine Kretz, Nicole Pezous, Jean‐Michel Rondeau, Nicolau Beckmann, Andreas Hartmann, Stefan Vormfelde, Olivier J David, Bruno Galli, Rita Ramos, Ana Graf, Cristina Lopez Lopez

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