Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer by Linling He, Xiaohe Lin, Natalia de Val, Natalia de Val, Natalia de Val, Karen L. Saye-Francisco, Karen L. Saye-Francisco, Colin J. Mann, Ryan Augst, Charles D. Morris, Parisa Azadnia, Bin Zhou, Devin Sok, Devin Sok, Devin Sok, Gabriel Ozorowski, Gabriel Ozorowski, Gabriel Ozorowski, Andrew B. Ward, Andrew B. Ward, Andrew B. Ward, Dennis R. Burton, Dennis R. Burton, Dennis R. Burton, Dennis R. Burton, Jiang Zhu, Jiang Zhu, Jiang Zhu

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Efficient isolation of rare B cells using next-generation antigen barcoding by Jonathan Hurtado, Jonathan Hurtado, Jonathan Hurtado, Claudia Flynn, Claudia Flynn, Claudia Flynn, Jeong Hyun Lee, Jeong Hyun Lee, Jeong Hyun Lee, Eugenia C. Salcedo, Eugenia C. Salcedo, Eugenia C. Salcedo, Christopher A. Cottrell, Christopher A. Cottrell, Christopher A. Cottrell, Christopher A. Cottrell, Patrick D. Skog, Dennis R. Burton, Dennis R. Burton, Dennis R. Burton, Dennis R. Burton, David Nemazee, William R. Schief, William R. Schief, William R. Schief, William R. Schief, William R. Schief, Elise Landais, Elise Landais, Elise Landais, Devin Sok, Devin Sok, Devin Sok, Bryan Briney, Bryan Briney, Bryan Briney, Bryan Briney

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Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines by Bartek Nogal, Matteo Bianchi, Christopher A. Cottrell, Robert N. Kirchdoerfer, Leigh M. Sewall, Hannah L. Turner, Fangzhu Zhao, Devin Sok, Dennis R. Burton, Lars Hangartner, Andrew B. Ward

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Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability by Leopold Kong, Linling He, Natalia de Val, Nemil Vora, Charles D. Morris, Parisa Azadnia, Devin Sok, Bin Zhou, Dennis R. Burton, Andrew B. Ward, Ian A. Wilson, Jiang Zhu

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Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer by Jeong Hyun Lee, Catherine Nakao, Michael Appel, Amber Le, Elise Landais, Oleksandr Kalyuzhniy, Xiaozhen Hu, Alessia Liguori, Tina-Marie Mullen, Bettina Groschel, Robert K. Abbott, Devin Sok, William R. Schief, Shane Crotty

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Neutralization diversity of HIV-1 Indian subtype C envelopes obtained from cross sectional and followed up individuals against broadly neutralizing monoclonal antibodies having dis... by Ranajoy Mullick, Jyoti Sutar, Nitin Hingankar, Suprit Deshpande, Madhuri Thakar, Seema Sahay, Rajesh P. Ringe, Sampurna Mukhopadhyay, Ajit Patil, Shubhangi Bichare, Kailapuri G. Murugavel, Aylur K. Srikrishnan, Rajat Goyal, Devin Sok, Jayanta Bhattacharya

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Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles by Linling He, Natalia de Val, Charles D. Morris, Nemil Vora, Therese C. Thinnes, Leopold Kong, Parisa Azadnia, Devin Sok, Bin Zhou, Dennis R. Burton, Ian A Wilson, David Nemazee, Andrew B. Ward, Jiang Zhu

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Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies. by Laura E McCoy, Emilia Falkowska, Katie J Doores, Khoa Le, Devin Sok, Marit J van Gils, Zelda Euler, Judith A Burger, Michael S Seaman, Rogier W Sanders, Hanneke Schuitemaker, Pascal Poignard, Terri Wrin, Dennis R Burton

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Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers by Charles D. Morris, Parisa Azadnia, Natalia de Val, Nemil Vora, Andrew Honda, Erick Giang, Karen Saye-Francisco, Yushao Cheng, Xiaohe Lin, Colin J. Mann, Jeffrey Tang, Devin Sok, Dennis R. Burton, Mansun Law, Andrew B. Ward, Linling He, Jiang Zhu

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Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. by Adriana Irimia, Andreia M Serra, Anita Sarkar, Ronald Jacak, Oleksandr Kalyuzhniy, Devin Sok, Karen L Saye-Francisco, Torben Schiffner, Ryan Tingle, Michael Kubitz, Yumiko Adachi, Robyn L Stanfield, Marc C Deller, Dennis R Burton, William R Schief, Ian A Wilson

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Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model by James E. Voss, Raiees Andrabi, Laura E. McCoy, Natalia de Val, Roberta P. Fuller, Terrence Messmer, Ching-Yao Su, Devin Sok, Salar N. Khan, Fernando Garces, Laura K. Pritchard, Richard T. Wyatt, Andrew B. Ward, Max Crispin, Ian A. Wilson, Dennis R. Burton

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Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model by James E. Voss, Raiees Andrabi, Laura E. McCoy, Natalia de Val, Roberta P. Fuller, Terrence Messmer, Ching-Yao Su, Devin Sok, Salar N. Khan, Fernando Garces, Laura K. Pritchard, Richard T. Wyatt, Andrew B. Ward, Max Crispin, Ian A. Wilson, Dennis R. Burton

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Reprogramming the antigen specificity of B cells using genome-editing technologies by James E Voss, Alicia Gonzalez-Martin, Raiees Andrabi, Roberta P Fuller, Ben Murrell, Laura E McCoy, Katelyn Porter, Deli Huang, Wenjuan Li, Devin Sok, Khoa Le, Bryan Briney, Morgan Chateau, Geoffrey Rogers, Lars Hangartner, Ann J Feeney, David Nemazee, Paula Cannon, Dennis R Burton

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Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer by Liwei Cao, Matthias Pauthner, Raiees Andrabi, Kimmo Rantalainen, Zachary Berndsen, Jolene K. Diedrich, Sergey Menis, Devin Sok, Raiza Bastidas, Sung-Kyu Robin Park, Claire M. Delahunty, Lin He, Javier Guenaga, Richard T. Wyatt, William R. Schief, Andrew B. Ward, John R. Yates, Dennis R. Burton, James C. Paulson

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Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer. by Rajesh Kumar, Suprit Deshpande, Leigh M Sewall, Gabriel Ozorowski, Christopher A Cottrell, Wen-Hsin Lee, Lauren G Holden, Sara T Richey, Antra Singh Chandrawacar, Kanika Dhiman, Ashish, Vivek Kumar, Shubbir Ahmed, Nitin Hingankar, Naresh Kumar, Kailapuri G Murugavel, Aylur K Srikrishnan, Devin Sok, Andrew B Ward, Jayanta Bhattacharya

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Global site-specific N-glycosylation analysis of HIV envelope glycoprotein by Liwei Cao, Jolene K. Diedrich, Daniel W. Kulp, Matthias Pauthner, Lin He, Sung-Kyu Robin Park, Devin Sok, Ching Yao Su, Claire M. Delahunty, Sergey Menis, Raiees Andrabi, Javier Guenaga, Erik Georgeson, Michael Kubitz, Yumiko Adachi, Dennis R. Burton, William R. Schief, John R. Yates III, James C. Paulson

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Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. by Pilar X Altman, Gabriel Ozorowski, Robyn L Stanfield, Jeremy Haakenson, Michael Appel, Mara Parren, Wen-Hsin Lee, Huldah Sang, Jordan Woehl, Karen Saye-Francisco, Leigh M Sewall, Collin Joyce, Ge Song, Katelyn Porter, Elise Landais, Raiees Andrabi, Ian A Wilson, Andrew B Ward, Waithaka Mwangi, Vaughn V Smider, Dennis R Burton, Devin Sok

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HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway by Robert Krause, Jumari Snyman, Hwa Shi-Hsia, Daniel Muema, Farina Karim, Yashica Ganga, Abigail Ngoepe, Yenzekile Zungu, Inbal Gazy, Mallory Bernstein, Khadija Khan, Matilda Mazibuko, Ntombifuthi Mthabela, Dirhona Ramjit, COMMIT-KZN Team, Oliver Limbo, Joseph Jardine, Devin Sok, Ian A Wilson, Willem Hanekom, Alex Sigal, Henrik Kløverpris, Thumbi Ndung'u, Alasdair Leslie

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Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways by Fangzhu Zhao, Celina Keating, Gabriel Ozorowski, Namir Shaabani, Irene M. Francino-Urdaniz, Shawn Barman, Oliver Limbo, Alison Burns, Panpan Zhou, Michael J. Ricciardi, Jordan Woehl, Quoc Tran, Hannah L. Turner, Linghang Peng, Deli Huang, David Nemazee, Raiees Andrabi, Devin Sok, John R. Teijaro, Timothy A. Whitehead, Andrew B. Ward, Dennis R. Burton, Joseph G. Jardine

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Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. by Jean-Philippe Julien, Devin Sok, Reza Khayat, Jeong Hyun Lee, Katie J Doores, Laura M Walker, Alejandra Ramos, Devan C Diwanji, Robert Pejchal, Albert Cupo, Umesh Katpally, Rafael S Depetris, Robyn L Stanfield, Ryan McBride, Andre J Marozsan, James C Paulson, Rogier W Sanders, John P Moore, Dennis R Burton, Pascal Poignard, Andrew B Ward, Ian A Wilson

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