Microglial inflammation and phagocytosis in Alzheimer's disease: potential therapeutic targets by Nizami, S, Hall-Roberts, H, Warrier, S, Cowley, S, Di Daniel, E

In vitro quantitative imaging assay for phagocytosis of dead neuroblastoma cells by iPSC-macrophages by Hall-Roberts, H, Di Daniel, E, James, WS, Davis, JB, Cowley, SA

Development of a high-content imaging-based technique to measure Dickkopf-1 binding to low-density lipoprotein receptor-related protein 6 by Priestley, R, Cheung, J, Murphy, E, Ehebauer, M, Davis, J, Di Daniel, E

Oscillating magnet array−based nanomagnetic gene transfection: A valuable tool for molecular neurobiology studies by Subramanian, M, Tyler, A, Luther, E, di Daniel, E, Lim, J, Dobson, J

A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6 by Priestley, RS, Cheung, J, Murphy, EJ, Ehebauer, MT, Davis, JB, Di Daniel, E

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation by Nizami, S, Millar, V, Arunasalam, K, Zarganes-Tzitzikas, T, Brough, D, Tresadern, G, Brennan, PE, Davis, JB, Ebner, D, Di Daniel, E

TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation by Fischer, FA, Mies, LFM, Nizami, S, Pantazi, E, Danielli, S, Demarco, B, Ohlmeyer, M, Lee, MSJ, Coban, C, Kagan, JC, Di Daniel, E, Bezbradica, JS

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function by Carling, PJ, Ryan, BJ, McGuinness, W, Kataria, S, Humble, SW, Milde, S, Duce, JA, Kapadia, N, Zuercher, WJ, Davis, JB, Di Daniel, E, Wade-Martins, R

TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages by Hall-Roberts, H, Di Daniel, E, Agarwal, D, Obst, J, Smith, TB, Monzón-Sandoval, J, Webber, C, James, WS, Mead, E, Davis, JB, Cowley, SA

Alzheimer’s disease drug discovery: targeting Dickkopf-1 induction of the Wnt-PCP non-canonical pathway by Johanssen, T, Wren, SP, Woffindale, C, Priestley, R, De Cesco, S, Ehebauer, MT, Dixon-Clarke, S, Katsouri, L, England, K, Bennet, JM, Fedorov, O, Brennan, PE, Di Daniel, E, Davis, JB

Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia by Liang, Z, Damianou, A, Vendrell, I, Jenkins, E, Lassen, FH, Washer, SJ, Grigoriou, A, Liu, G, Yi, G, Lou, H, Cao, F, Zheng, X, Fernandes, RA, Dong, T, Tate, EW, Di Daniel, E, Kessler, BM

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain by Szykowska, A, Chen, Y, Smith, TB, Preger, C, Yang, J, Qian, D, Mukhopadhyay, SM, Wigren, E, Neame, SJ, Gräslund, S, Persson, H, Atkinson, PJ, Di Daniel, E, Mead, E, Wang, J, Davis, JB, Burgess-Brown, NA, Bullock, AN