Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes. by Valdes, A, McWilliams, D, Arden, N, Doherty, SA, Wheeler, M, Muir, K, Zhang, W, Cooper, C, Maciewicz, R, Doherty, M

Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis. by Valdes, A, Spector, T, Tamm, A, Kisand, K, Doherty, SA, Dennison, E, Mangino, M, Tamm, A, Kerna, I, Hart, D, Wheeler, M, Cooper, C, Lories, R, Arden, N, Doherty, M

Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain. by Valdes, A, Arden, N, Vaughn, F, Doherty, SA, Leaverton, P, Zhang, W, Muir, K, Rampersaud, E, Dennison, E, Edwards, M, Jameson, K, Javaid, M, Spector, T, Cooper, C, Maciewicz, R, Doherty, M

The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study. by Panoutsopoulou, K, Metrustry, S, Doherty, SA, Laslett, L, Maciewicz, R, Hart, D, Zhang, W, Muir, K, Wheeler, M, Cooper, C, Spector, T, Cicuttini, F, Jones, G, Arden, N, Doherty, M, Zeggini, E, Valdes, A

Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis. by Neogi, T, Soni, A, Doherty, SA, Laslett, L, Maciewicz, R, Hart, D, Zhang, W, Muir, K, Wheeler, M, Cooper, C, Spector, T, Cicuttini, F, Jones, G, Nevitt, M, Liu, Y, Arden, N, Doherty, M, Valdes, A

The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis. by Valdes, A, De Wilde, G, Doherty, SA, Lories, R, Vaughn, F, Laslett, L, Maciewicz, R, Soni, A, Hart, D, Zhang, W, Muir, K, Dennison, E, Wheeler, M, Leaverton, P, Cooper, C, Spector, T, Cicuttini, F, Chapman, V, Jones, G, Arden, N, Doherty, M

The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis. by Valdes, A, De Wilde, G, Doherty, SA, Lories, R, Vaughn, F, Laslett, L, Maciewicz, R, Soni, A, Hart, D, Zhang, W, Muir, K, Dennison, E, Wheeler, M, Leaverton, P, Cooper, C, Spector, T, Cicuttini, F, Chapman, V, Jones, G, Arden, N, Doherty, M

The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance. by Valdes, A, Evangelou, E, Kerkhof, H, Tamm, A, Doherty, SA, Kisand, K, Tamm, A, Kerna, I, Uitterlinden, A, Hofman, A, Rivadeneira, F, Cooper, C, Dennison, E, Zhang, W, Muir, K, Ioannidis, J, Wheeler, M, Maciewicz, R, van Meurs, J, Arden, N, Spector, T, Doherty, M

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. by Betancourt, C, Cailotto, F, Kerkhof, H, Cornelis, F, Doherty, SA, Hart, D, Hofman, A, Luyten, F, Maciewicz, R, Mangino, M, Metrustry, S, Muir, K, Peters, M, Rivadeneira, F, Wheeler, M, Zhang, W, Arden, N, Spector, T, Uitterlinden, A, Doherty, M, Lories, R, Valdes, A, van Meurs, J

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoar... by Kerkhof, H, Doherty, M, Arden, N, Abramson, S, Attur, M, Bos, S, Cooper, C, Dennison, E, Doherty, SA, Evangelou, E, Hart, D, Hofman, A, Javaid, M, Kerna, I, Kisand, K, Kloppenburg, M, Krasnokutsky, S, Maciewicz, R, Meulenbelt, I, Muir, K, Rivadeneira, F, Samuels, J, Sezgin, M, Slagboom, E, Smith, A

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoar... by Kerkhof, H, Doherty, M, Arden, N, Abramson, S, Attur, M, Bos, S, Cooper, C, Dennison, E, Doherty, SA, Evangelou, E, Hart, D, Hofman, A, Javaid, K, Kerna, I, Kisand, K, Kloppenburg, M, Krasnokutsky, S, Maciewicz, R, Meulenbelt, I, Muir, K, Rivadeneira, F, Samuels, J, Sezgin, M, Slagboom, E, Smith, A

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium. by Kerkhof, H, Meulenbelt, I, Akune, T, Arden, N, Aromaa, A, Bierma-Zeinstra, S, Carr, A, Cooper, C, Dai, J, Doherty, M, Doherty, SA, Felson, D, Gonzalez, A, Gordon, A, Harilainen, A, Hart, D, Hauksson, V, Heliovaara, M, Hofman, A, Ikegawa, S, Ingvarsson, T, Jiang, Q, Jonsson, H, Jonsdottir, I, Kawaguchi, H

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium. by Kerkhof, H, Meulenbelt, I, Akune, T, Arden, N, Aromaa, A, Bierma-Zeinstra, S, Carr, A, Cooper, C, Dai, J, Doherty, M, Doherty, SA, Felson, D, Gonzalez, A, Gordon, A, Harilainen, A, Hart, D, Hauksson, V, Heliovaara, M, Hofman, A, Ikegawa, S, Ingvarsson, T, Jiang, Q, Jonsson, H, Jonsdottir, I, Kawaguchi, H

LARGE SCALE META-ANALYSIS OF INTERLEUKIN-1 BETA AND INTERLEUKIN-1 RECEPTOR ANTAGONIST POLYMORPHISMS ON RISK OF RADIOGRAPHIC HIP AND KNEE OSTEOARTHRITIS AND SEVERITY OF KNEE OSTEOAR... by Kerkhof, H, Doherty, M, Abramson, S, Arden, N, Attur, M, Bos, S, Cooper, C, Doherty, SA, Evangelou, E, Kerna, I, Kisand, K, Kloppenburg, M, Maciewicz, R, Meulenbelt, I, Sezgin, M, Slagboom, E, Smith, A, Spector, T, Tamm, A, Tamm, A, Uitterlinden, A, Wheeler, M, Zhang, W, van Meurs, J, Valdes, A

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations. by Valdes, A, Styrkarsdottir, U, Doherty, M, Morris, D, Mangino, M, Tamm, A, Doherty, SA, Kisand, K, Kerna, I, Tamm, A, Wheeler, M, Maciewicz, R, Zhang, W, Muir, K, Dennison, E, Hart, D, Metrustry, S, Jonsdottir, I, Jonsson, G, Jonsson, H, Ingvarsson, T, Cooper, C, Vyse, T, Spector, T, Stefansson, K, Arden, N

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium by Kerkhof, H, Meulenbelt, I, Akune, T, Arden, N, Aromaa, A, Bierma-Zeinstra, SMA, Carr, A, Cooper, C, Dai, J, Doherty, M, Doherty, SA, Felson, D, Gonzalez, A, Gordon, A, Harilainen, A, Hart, D, Hauksson, V, Heliovaara, M, Hofman, A, Ikegawa, S, Ingvarsson, T, Jiang, Q, Jonsson, H, Jonsdottir, I, Kawaguchi, H