Replication of extended lifespan phenotype in mice with deletion of insulin receptor substrate 1. by Colin Selman, Linda Partridge, Dominic J Withers

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Calcium Channel CaV2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons by Mark A. Smith, Loukia Katsouri, Samuel Virtue, Agharul I. Choudhury, Antonio Vidal-Puig, Michael L.J. Ashford, Dominic J. Withers

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PINK1 deficiency in β-cells increases basal insulin secretion and improves glucose tolerance in mice by Emma Deas, Kaisa Piipari, Asif Machhada, Abi Li, Ana Gutierrez-del-Arroyo, Dominic J. Withers, Nicholas W. Wood, Andrey Y. Abramov

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Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. by Cathy Slack, Christian Werz, Daniela Wieser, Nazif Alic, Andrea Foley, Hugo Stocker, Dominic J Withers, Janet M Thornton, Ernst Hafen, Linda Partridge

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Differential pre-mRNA splicing regulates Nnat isoforms in the hypothalamus after gastric bypass surgery in mice. by William R Scott, Cigdem Gelegen, Keval Chandarana, Efthimia Karra, Ahmed Yousseif, Chloé Amouyal, Agharul I Choudhury, Fabrizio Andreelli, Dominic J Withers, Rachel L Batterham

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Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity. by Derek A Costello, Marc Claret, Hind Al-Qassab, Florian Plattner, Elaine E Irvine, Agharul I Choudhury, K Peter Giese, Dominic J Withers, Paola Pedarzani

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Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice by Seok-Ting J. Ang, Elisa M. Crombie, Han Dong, Kuan-Ting Tan, Adriel Hernando, Dejie Yu, Stuart Adamson, Seonyoung Kim, Dominic J. Withers, Hua Huang, Shih-Yin Tsai

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Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice by Steven J. Millership, Simon J. Tunster, Mathew Van de Pette, Agharul I. Choudhury, Elaine E. Irvine, Mark Christian, Amanda G. Fisher, Rosalind M. John, James Scott, Dominic J. Withers

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Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes by Chiara Prodani, Elaine E. Irvine, Alessandro Sardini, Hannah J. Gleneadie, Andrew Dimond, Mathew Van de Pette, Rosalind John, Michelle Kokkinou, Oliver Howes, Dominic J. Withers, Mark A. Ungless, Matthias Merkenschlager, Amanda G. Fisher

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Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice by Mark A. Smith, Loukia Katsouri, Elaine E. Irvine, Mohammed K. Hankir, Silvia M.A. Pedroni, Peter J. Voshol, Matthew W. Gordon, Agharul I. Choudhury, Angela Woods, Antonio Vidal-Puig, David Carling, Dominic J. Withers

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Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH by Suchira Gallage, Adnan Ali, Jose Efren Barragan Avila, Diran Herebian, Mohammad M. Karimi, Elaine E. Irvine, Domhnall McHugh, Anne T. Schneider, Mihael Vucur, Verena Keitel, Jesús Gil, Dominic J. Withers, Tom Luedde, Mathias Heikenwalder

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Detection of senescence using machine learning algorithms based on nuclear features by Imanol Duran, Joaquim Pombo, Bin Sun, Suchira Gallage, Hiromi Kudo, Domhnall McHugh, Laura Bousset, Jose Efren Barragan Avila, Roberta Forlano, Pinelopi Manousou, Mathias Heikenwalder, Dominic J. Withers, Santiago Vernia, Robert D. Goldin, Jesús Gil

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Evaluation of Intraperitoneal [18F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity by Els F. Halff, Sridhar Natesan, David R. Bonsall, Mattia Veronese, Anna Garcia-Hidalgo, Michelle Kokkinou, Sac-Pham Tang, Laura J. Riggall, Roger N. Gunn, Elaine E. Irvine, Dominic J. Withers, Lisa A. Wells, Oliver D. Howes

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Activation of eIF4E‐binding‐protein‐1 rescues mTORC1‐induced sarcopenia by expanding lysosomal degradation capacity by Elisa M. Crombie, Seonyoung Kim, Stuart Adamson, Han Dong, Tzu‐Chiao Lu, Yiju Wu, Yajun Wu, Yotam Levy, Nolan Stimple, Wing Moon R. Lam, Hwee Weng D. Hey, Dominic J. Withers, Ao‐Lin Hsu, Boon Huat Bay, Julien Ochala, Shih‐Yin Tsai

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Modulation of SF1 Neuron Activity Coordinately Regulates Both Feeding Behavior and Associated Emotional States by Paulius Viskaitis, Elaine E. Irvine, Mark A. Smith, Agharul I. Choudhury, Elisa Alvarez-Curto, Justyna A. Glegola, Darran G. Hardy, Silvia M.A. Pedroni, Maria R. Paiva Pessoa, Anushka B.P. Fernando, Loukia Katsouri, Alessandro Sardini, Mark A. Ungless, Graeme Milligan, Dominic J. Withers

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Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity by Marie-Therese Rached, Steven J. Millership, Silvia M.A. Pedroni, Agharul I. Choudhury, Ana S.H. Costa, Darran G. Hardy, Justyna A. Glegola, Elaine E. Irvine, Colin Selman, Megan C. Woodberry, Vijay K. Yadav, Sanjay Khadayate, Antonio Vidal-Puig, Samuel Virtue, Christian Frezza, Dominic J. Withers

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Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint Mis-regulation in Adults by Mathew Van de Pette, Allifia Abbas, Amelie Feytout, Gráinne McNamara, Ludovica Bruno, Wilson K. To, Andrew Dimond, Alessandro Sardini, Zoe Webster, James McGinty, Eleanor J. Paul, Mark A. Ungless, Paul M.W. French, Dominic J. Withers, Anthony Uren, Anne C. Ferguson-Smith, Matthias Merkenschlager, Rosalind M. John, Amanda G. Fisher

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