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MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment by Douglas D. Fang, Qiuqiong Tang, Yanhui Kong, Qixin Wang, Jiaxing Gu, Xu Fang, Peng Zou, Tao Rong, Jingwen Wang, Dajun Yang, Yifan Zhai
Published 2019-11-01
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MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models by Douglas D. Fang, Qiuqiong Tang, Yanhui Kong, Tao Rong, Qixin Wang, Na Li, Xu Fang, Jiaxing Gu, Dengkun Xiong, Yan Yin, Jing Deng, Dajun Yang, Yifan Zhai
Published 2021-05-01
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Discovery of a novel ALK/ROS1/FAK inhibitor, APG-2449, in preclinical non-small cell lung cancer and ovarian cancer models by Douglas D. Fang, Ran Tao, Guangfeng Wang, Yuanbao Li, Kaixiang Zhang, Chunhua Xu, Guoqin Zhai, Qixin Wang, Jingwen Wang, Chunyang Tang, Ping Min, Dengkun Xiong, Jianyong Chen, Shaomeng Wang, Dajun Yang, Yifan Zhai
Published 2022-07-01
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Preclinical development of HQP1351, a multikinase inhibitor targeting a broad spectrum of mutant KIT kinases, for the treatment of imatinib-resistant gastrointestinal stromal tumor... by Xuechao Liu, Guangfeng Wang, Xianglei Yan, Haibo Qiu, Ping Min, Miaoyi Wu, Chunyang Tang, Fei Zhang, Qiuqiong Tang, Saijie Zhu, Miaozhen Qiu, Wei Zhuang, Douglas D. Fang, Zhiwei Zhou, Dajun Yang, Yifan Zhai
Published 2019-10-01
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Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation. by Douglas D Fang, Cathy C Zhang, Yin Gu, Jitesh P Jani, Joan Cao, Konstantinos Tsaparikos, Jing Yuan, Melissa Thiel, Amy Jackson-Fisher, Qing Zong, Patrick B Lappin, Tomoko Hayashi, Richard B Schwab, Anthony Wong, Annette John-Baptiste, Shubha Bagrodia, Geritt Los, Steve Bender, James Christensen, Todd Vanarsdale
Published 2013-01-01
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