The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using en... by Tsoumpra, MK, Muniz, JR, Barnett, BL, Kwaasi, AA, Pilka, ES, Kavanagh, KL, Evdokimov, A, Walter, RL, Von Delft, F, Ebetino, FH, Oppermann, U, Russell, RGG, Dunford, JE

BRD9-containing non-canonical BAF complex maintains somatic cell transcriptome and acts as a barrier to human reprogramming by Sevinç, K, Sevinç, GG, Cavga, AD, Philpott, M, Kelekçi, S, Can, H, Cribbs, AP, Yıldız, AB, Yılmaz, A, Ayar, ES, Arabacı, DH, Dunford, JE, Ata, D, Sigua, LH, Qi, J, Oppermann, U, Onder, TT

KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas by Heward, JA, Koniali, L, D'Avola, A, Close, K, Yeomans, A, Philpott, M, Dunford, JE, Rahim, T, Al Seraihi, AF, Wang, J, Korfi, K, Araf, S, Iqbal, S, Bewicke-Copley, F, Kumar, E, Barisic, D, Calaminici, M, Clear, AJ, Gribben, JG, Johnson, PWM, Neve, RM, Cutillas, PR, Okosun, J, Oppermann, U, Melnick, A, Packham, G, Fitzgibbon, J

GGPS1 mutations cause muscular dystrophy/hearing loss/ovarian insufficiency syndrome by Foley, AR, Zou, Y, Dunford, JE, Rooney, J, Chandra, G, Xiong, H, Straub, V, Voit, T, Romero, N, Donkervoort, S, Hu, Y, Markello, T, Horn, A, Qebibo, L, Dastgir, J, Meilleur, KG, Finkel, RS, Fan, Y, Mamchaoui, K, Duguez, S, Nelson, I, Laporte, J, Santi, M, Malfatti, E, Maisonobe, T, Touraine, P, Hirano, M, Hughes, I, Bushby, K, Oppermann, U, Böhm, J, Jaiswal, JK, Stojkovic, T, Bönnemann, CG

Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases by Pagnamenta, AT, Camps, C, Giacopuzzi, E, Taylor, JM, Hashim, M, Calpena, E, Kaisaki, PJ, Hashimoto, A, Yu, J, Sanders, E, Schwessinger, R, Hughes, JR, Lunter, G, Dreau, H, Ferla, M, Lange, L, Kesim, Y, Ragoussis, V, Vavoulis, DV, Allroggen, H, Ansorge, O, Babbs, C, Banka, S, Baños-Piñero, B, Beeson, D, Ben-Ami, T, Bennett, DL, Bento, C, Blair, E, Brasch-Andersen, C, Bull, KR, Cario, H, Cilliers, D, Conti, V, Davies, EG, Dhalla, F, Dacal, BD, Dong, Y, Dunford, JE, Guerrini, R, Harris, AL, Hartley, J, Hollander, G, Javaid, K, Kane, M, Kelly, D, Kelly, D, Knight, SJL, Kreins, AY, Kvikstad, EM, Lines, KE, Lord, SR, Lu, X, Marsden, B, Ormondroyd, E, Stevenson, M, Twigg, SRF, Uhlig, HH, Watkins, H, Schuh, AH, Wilkie, AOM, Taylor, JC