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Reversible linkage of two distinct small molecule inhibitors of Myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines. by Jutta Wanner, Darlene Romashko, Douglas S Werner, Earl W May, Yue Peng, Ryan Schulz, Kenneth W Foreman, Suzanne Russo, Lee D Arnold, Maneesh Pingle, Donald E Bergstrom, Francis Barany, Stuart Thomson
Published 2015-01-01
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Linking ATP and allosteric sites to achieve superadditive binding with bivalent EGFR kinase inhibitors by Florian Wittlinger, Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner, Brandon T. Oligny, Surbhi P. Chitnis, Tyler S. Beyett, Alexander Rasch, Brian Buckley, Daniel A. Urul, Tatiana Shaurova, Earl W. May, Erik M. Schaefer, Michael J. Eck, Pamela A. Hershberger, Antti Poso, Stefan A. Laufer, David E. Heppner
Published 2024-02-01
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