Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing by Heckl, Dirk, Kowalczyk, Monika S., Yudovich, David, Belizaire, Roger, Puram, Rishi V., McConkey, Marie, Thielke, Anne, Aster, Jon C., Regev, Aviv, Ebert, Benjamin L.

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Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells by Kowalczyk, Monika S., Tirosh, Itay, Heckl, Dirk, Rao, Tata Nageswara, Dixit, Atray, Haas, Brian J., Schneider, Rebekka K., Wagers, Amy J., Ebert, Benjamin L., Regev, Aviv

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Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with by Ajore, Ram, Raiser, David, McConkey, Marie, Jöud, Magnus, Boidol, Bernd, Mar, Brenton, Saksena, Gordon, Weinstock, David M, Armstrong, Scott, Ellis, Steven R, Ebert, Benjamin L, Nilsson, Bjorn

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Implantable microenvironments to attract hematopoietic stem/cancer cells by Lee, Jungwoo, Li, Matthew, Milwid, Jack, Dunham, Joshua, Vinegoni, Claudio, Gorbatov, Rostic, Iwamoto, Yoshiko, Wang, Fangjing, Shen, Keyue, Hatfield, Kimberley, Enger, Marianne, Shafiee, Sahba, McCormack, Emmet, Ebert, Benjamin L., Weissleder, Ralph, Yarmush, Martin L., Parekkadan, Biju

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Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML by Puram, Rishi V., Kowalczyk, Monika S., de Boer, Carl G., Schneider, Rebekka K., Miller, Peter G., McConkey, Marie, Tothova, Zuzana, Tejero, Héctor, Heckl, Dirk, Järås, Marcus, Chen, Michelle C., Li, Hubo, Tamayo, Alfred, Cowley, Glenn S., Rozenblatt-Rosen, Orit, Al-Shahrour, Fatima, Ebert, Benjamin L., Regev, Aviv

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Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia by Kharas, Michael G., Lengner, Christopher J., Al-Shahrour, Fatima, Bullinger, Lars, Ball, Brian, Zaidi, Samir, Morgan, Kelly, Tam, Winnie, Paktinat, Mahnaz, Okabe, Rachel, Gozo, Maricel, Einhorn, William S., Lane, Steven W., Scholl, Claudia, Frohling, Stefan, Fleming, Mark, Ebert, Benjamin L., Gilliland, D. Gary, Jaenisch, Rudolf, Daley, George Q.

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Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide by Jan, Max, Scarfò, Irene, Larson, Rebecca C, Walker, Amanda, Schmidts, Andrea, Guirguis, Andrew A, Gasser, Jessica A, Słabicki, Mikołaj, Bouffard, Amanda A, Castano, Ana P, Kann, Michael C, Cabral, Maria L, Tepper, Alexander, Grinshpun, Daniel E, Sperling, Adam S, Kyung, Taeyoon, Sievers, Quinlan L, Birnbaum, Michael E, Maus, Marcela V, Ebert, Benjamin L

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Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia by Taylor, Alison M, Macari, Elizabeth R, Chan, Iris T, Blair, Megan C, Doulatov, Sergei, Vo, Linda T, Raiser, David M, Siva, Kavitha, Basak, Anindita, Pirouz, Mehdi, Shah, Arish N, McGrath, Katherine, Humphries, Jessica M, Stillman, Emma, Alter, Blanche P, Calo, Eliezer, Gregory, Richard I, Sankaran, Vijay G, Flygare, Johan, Ebert, Benjamin L, Zhou, Yi, Daley, George Q, Zon, Leonard I

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Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors by Doulatov, Sergei, Vo, Linda T., Macari, Elizabeth R., Wahlster, Lara, Kinney, Melissa A., Taylor, Alison M., Barragan, Jessica, Gupta, Manav, McGrath, Katherine, Humphries, Jessica M., DeVine, Alex, Narla, Anupama, Alter, Blanche P., Beggs, Alan H., Agarwal, Suneet, Ebert, Benjamin L., Gazda, Hanna T., Sieff, Colin A., Schlaeger, Thorsten M., Zon, Leonard I., Daley, George Q., Lee, Hsiang-Ying, Lodish, Harvey F

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Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis by Novershtern, Noa, Subramanian, Aravind, Lawton, Lee N., Mak, Raymond H., Haining, W. Nicholas, McConkey, Marie, Habib, Naomi, Yosef, Nir, Chang, Cindy Y., Shay, Tal, Frampton, Garrett M., Leskov, Ilya B., Nilsson, Bjorn, Preffer, Fred, Dombkowski, David, Evans, John W., Liefeld, Ted, Smutko, John S., Chen, Jianzhu, Friedman, Nir, Young, Richard A., Golub, Todd R., Regev, Aviv, Ebert, Benjamin L., Drake, Adam

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Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability by Paolella, Brenton R, Urbanski, Laura M, Alberta, John A, Bandopadhayay, Pratiti, Nichols, Caitlin A, Agarwalla, Pankaj K, Brown, Meredith S, Lamothe, Rebecca, Yu, Yong, Choi, Peter S, Obeng, Esther A, Heckl, Dirk, Vazquez, Francisca, Buhrlage, Sara J, Stiles, Charles D, Reed, Robin, Gibson, William J, Zack, Travis Ian, Wei, Guo, Wang, Belinda, Tsherniak, Aviad, Weir, Barbara A, Root, David, Cowley, Glenn S, Ebert, Benjamin L, Hahn, William, Beroukhim, Rameen

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In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling by Miller, Peter G., Al-Shahrour, Fatima, Hartwell, Kimberly A., Chu, Lisa P., Jaras, Marcus, Puram, Rishi V., Puissant, Alexandre, Callahan, Kevin P., Ashton, John, McConkey, Marie, Poveromo, Luke P., Cowley, Glenn S., Kharas, Michael G., Labelle, Myriam, Shterental, Sebastian, Fujisaki, Joji, Silberstein, Lev, Alexe, Gabriela, Al-Hajj, Muhammad A., Shelton, Christopher A., Armstrong, Scott A., Root, David E., Scadden, David T., Mukherjee, Siddhartha, Stegmaier, Kimberly, Jordan, Craig T., Ebert, Benjamin L., Hynes, Richard O

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Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription by Struntz, Nicholas B., Chen, Andrew I, Deutzmann, Anja, Wilson, Robert M., Stefan, Eric, Evans, Helen L, Ramirez, Maricela A., Liang, Tong, Caballero, Francisco, Wildschut, Mattheus H.E., Neel, Dylan V, Freeman, David B., Pop, Marius S, McConkey, Marie, Muller, Sandrine, Curtin, Brice Harrison, Tseng, Hanna, Frombach, Kristen R., Butty, Vincent L G, Levine, Stuart S., Feau, Clementine, Elmiligy, Sarah, Hong, Jiyoung A., Lewis, Timothy A., Vetere, Amedeo, Clemons, Paul A., Malstrom, Scott E., Ebert, Benjamin L., Lin, Charles Y., Felsher, Dean W., Koehler, Angela Nicole

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