Autoimmune Diseases in the Bioinformatics Paradigm by Quan-Zhen Li, Edward K. Wakeland

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T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells by Aakanksha Jain, Ran Song, Edward K. Wakeland, Chandrashekhar Pasare

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Distinct patterns of innate immune activation by clinical isolates of respiratory syncytial virus. by Ruth Levitz, Yajing Gao, Igor Dozmorov, Ran Song, Edward K Wakeland, Jeffrey S Kahn

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Genomic Heterogeneity of Methicillin Resistant Staphylococcus aureus Associated with Variation in Severity of Illness among Children with Acute Hematogenous Osteomyelitis. by Claudia Gaviria-Agudelo, Chukwuemika Aroh, Naureen Tareen, Edward K Wakeland, MinSoo Kim, Lawson A Copley

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907 ANA associated regulatory polymorphisms in HLA class III region downregulate complement 4 (C4) gene expression by David R Karp, Prithvi Raj, Edward K Wakeland, Chaoying Liang, Carlos Arana, Quan-Zhen Li, Nicolai van Oers

The impact of Staphylococcus aureus genomic variation on clinical phenotype of children with acute hematogenous osteomyelitis by Angela Collins, Edward K. Wakeland, Prithvi Raj, Min S. Kim, Jiwoong Kim, Naureen G. Tareen, Lawson A.B. Copley

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Influence of Carbon Monoxide on Growth and Apoptosis of Human Umbilical Artery Smooth Muscle Cells and Vein Endothelial Cells by Yajuan Li, Hai Wang, Bin Yang, Jichen Yang, Xiuyan Ruan, Yadong Yang, Edward K. Wakeland, Quanzhen Li, Xiangdong Fang

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Few single nucleotide variations in exomes of human cord blood induced pluripotent stem cells. by Rui-Jun Su, Yadong Yang, Amanda Neises, Kimberly J Payne, Jasmin Wang, Kasthuribai Viswanathan, Edward K Wakeland, Xiangdong Fang, Xiao-Bing Zhang

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Complete genome analysis of three Acinetobacter baumannii clinical isolates in China for insight into the diversification of drug resistance elements. by Lingxiang Zhu, Zhongqiang Yan, Zhaojun Zhang, Qiming Zhou, Jinchun Zhou, Edward K Wakeland, Xiangdong Fang, Zhenyu Xuan, Dingxia Shen, Quan-Zhen Li

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T-cell tolerant fraction as a predictor of immune-related adverse events by Yang Xie, Shaheen Khan, Prithvi Raj, Edward K Wakeland, Mitchell S von Itzstein, Farjana Fattah, Jason Y Park, David Hsiehchen, Jared Ostmeyer, David E Gerber, Mary Gwin, Rodrigo Catalan

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IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility by Ran Song, Yajing Gao, Igor Dozmorov, Venkat Malladi, Irene Saha, Margaret M. McDaniel, Sreeja Parameswaran, Chaoying Liang, Carlos Arana, Bo Zhang, Benjamin Wakeland, Jinchun Zhou, Matthew T. Weirauch, Leah C. Kottyan, Edward K. Wakeland, Chandrashekhar Pasare

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Systemic immune parameters after prior radiation therapy in patients receiving immune checkpoint inhibitors by Vatsala Mundra, Yuqiu Yang, Mitchell S. von Itzstein, Farjana Fattah, Amrit S. Gonugunta, Raquibul Hannan, Laurentiu M. Pop, Yuanyuan Zhang, Yiqing Wang, Thomas Sheffield, Yang Xie, Jonathan E. Dowell, Jade Homsi, Sawsan Rashdan, Jason Park, Quan-Zhen Li, Edward K. Wakeland, David E. Gerber

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Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells by Satoko Arai, Natsumi Maehara, Yoshihiro Iwamura, Shin-ichiro Honda, Katsuhiko Nakashima, Toshihiro Kai, Masato Ogishi, Kumiko Morita, Jun Kurokawa, Mayumi Mori, Yuji Motoi, Kensuke Miyake, Nobuyuki Matsuhashi, Ken-ichi Yamamura, Osamu Ohara, Akira Shibuya, Edward K. Wakeland, Quan-Zhen Li, Toru Miyazaki

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SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature. by Amy M Becker, Kathryn H Dao, Bobby Kwanghoon Han, Roger Kornu, Shuchi Lakhanpal, Angela B Mobley, Quan-Zhen Li, Yun Lian, Tianfu Wu, Andreas M Reimold, Nancy J Olsen, David R Karp, Fatema Z Chowdhury, J David Farrar, Anne B Satterthwaite, Chandra Mohan, Peter E Lipsky, Edward K Wakeland, Laurie S Davis

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Association between Antibiotic Exposure and Systemic Immune Parameters in Cancer Patients Receiving Checkpoint Inhibitor Therapy by Mitchell S. von Itzstein, Amrit S. Gonugunta, Thomas Sheffield, Jade Homsi, Jonathan E. Dowell, Andrew Y. Koh, Prithvi Raj, Farjana Fattah, Yiqing Wang, Vijay S. Basava, Shaheen Khan, Jason Y. Park, Vinita Popat, Jessica M. Saltarski, Yvonne Gloria-McCutchen, David Hsiehchen, Jared Ostmeyer, Yang Xie, Quan-Zhen Li, Edward K. Wakeland, David E. Gerber

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902 Loss-of-function variants in SAT1 cause X-linked Childhood-onset Systemic Lupus Erythematosus by Jim C Oates, Qing Sun, Joel M Guthridge, Judith A James, Lei Wang, Diane L Kamen, Fang Wang, Miaojia Zhang, Gary S Gilkeson, Deborah K McCurdy, Lingxiao Xu, Wenfeng Tan, Jian Zhao, Ting Liu, Bevra H Hahn, Betty P Tsao, R Hal Scofield, Yun Deng, Prithvi Raj, Edward K Wakeland, Linyu Geng, Xue Xu, Yunjuan Wu, Jingfeng Zhu, Alexander Awgulewitsch

Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus by Prithvi Raj, Ran Song, Honglin Zhu, Linley Riediger, Dong-Jae Jun, Chaoying Liang, Carlos Arana, Bo Zhang, Yajing Gao, Benjamin E. Wakeland, Igor Dozmorov, Jinchun Zhou, Jennifer A. Kelly, Bernard R. Lauwerys, Joel M. Guthridge, Nancy J. Olsen, Swapan K. Nath, Chandrashekhar Pasare, Nicolai van Oers, Gary Gilkeson, Betty P. Tsao, Patrick M. Gaffney, Peter K. Gregersen, Judith A. James, Xiaoxia Zuo, David R. Karp, Quan-Zhen Li, Edward K. Wakeland

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Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity by Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A Wise, John B Harley, Swapan K Nath, Judith A James, Chaim O Jacob, Betty P Tsao, Chandrashekhar Pasare, David R Karp, Quan Zhen Li, Patrick M Gaffney, Edward K Wakeland

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Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians. by Julio E Molineros, Loren L Looger, Kwangwoo Kim, Yukinori Okada, Chikashi Terao, Celi Sun, Xu-Jie Zhou, Prithvi Raj, Yuta Kochi, Akari Suzuki, Shuji Akizuki, Shuichiro Nakabo, So-Young Bang, Hye-Soon Lee, Young Mo Kang, Chang-Hee Suh, Won Tae Chung, Yong-Beom Park, Jung-Yoon Choe, Seung-Cheol Shim, Shin-Seok Lee, Xiaoxia Zuo, Kazuhiko Yamamoto, Quan-Zhen Li, Nan Shen, Lauren L Porter, John B Harley, Kek Heng Chua, Hong Zhang, Edward K Wakeland, Betty P Tsao, Sang-Cheol Bae, Swapan K Nath

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Transancestral mapping and genetic load in systemic lupus erythematosus by Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse

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