Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment by Jonathan Aow, Tzu-Rung Huang, Yeek Teck Goh, Alfred Xuyang Sun, Gopal Thinakaran, Edward H. Koo

Get full text

Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's disease. by Scott A Wilke, Tara Raam, Joseph K Antonios, Eric A Bushong, Edward H Koo, Mark H Ellisman, Anirvan Ghosh

Get full text

Independent relationship between amyloid precursor protein (APP) dimerization and γ-secretase processivity. by Joo In Jung, Sasha Premraj, Pedro E Cruz, Thomas B Ladd, Yewon Kwak, Edward H Koo, Kevin M Felsenstein, Todd E Golde, Yong Ran

Get full text

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity by Sandra Schilling, Ajay Pradhan, Amelie Heesch, Andrea Helbig, Kaj Blennow, Christian Koch, Lea Bertgen, Edward H. Koo, Gunnar Brinkmalm, Henrik Zetterberg, Stefan Kins, Simone Eggert

Get full text

APP family member dimeric complexes are formed predominantly in synaptic compartments by Sandra Schilling, Alexander August, Mathieu Meleux, Carolin Conradt, Luisa M. Tremmel, Sandra Teigler, Virginie Adam, Ulrike C. Müller, Edward H. Koo, Stefan Kins, Simone Eggert

Get full text

A Role for Presenilin 1 in Regulating the Delivery of Amyloid Precursor Protein to the Cell Surface by Jae Yoon Leem, Carlos A. Saura, Claus Pietrzik, John Christianson, Christian Wanamaker, LaShaunda T. King, Margaret L. Veselits, Taisuke Tomita, Laura Gasparini, Takeshi Iwatsubo, Huaxi Xu, William N. Green, Edward H. Koo, Gopal Thinakaran

Get full text

Machine learning classifies predictive kinematic features in a mouse model of neurodegeneration by Ruyi Huang, Ali A. Nikooyan, Bo Xu, M. Selvan Joseph, Hamidreza Ghasemi Damavandi, Nathan von Trotha, Lilian Li, Ashok Bhattarai, Deeba Zadeh, Yeji Seo, Xingquan Liu, Patrick A. Truong, Edward H. Koo, J. C. Leiter, Daniel C. Lu

Get full text

Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer’s Disease-like Pathology by Jeffrey N. Savas, Yi-Zhi Wang, Laura A. DeNardo, Salvador Martinez-Bartolome, Daniel B. McClatchy, Timothy J. Hark, Natalie F. Shanks, Kira A. Cozzolino, Mathieu Lavallée-Adam, Samuel N. Smukowski, Sung Kyu Park, Jeffery W. Kelly, Edward H. Koo, Terunaga Nakagawa, Eliezer Masliah, Anirvan Ghosh, John R. Yates, III

Get full text