Disruption of IL-33 Signaling Limits Early CD8+ T Cell Effector Function Leading to Exhaustion in Murine Hemophagocytic Lymphohistiocytosis by Julia E. Rood, Julia E. Rood, Thomas N. Burn, Thomas N. Burn, Vanessa Neal, Niansheng Chu, Edward M. Behrens, Edward M. Behrens

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509 AMG487, A CXCR3 Antagonist, changes the Inflammatory Milieu in Familial Hemophagocytic Lymphohistiocytosis (FHL) Hepatitis by Tamir Diamond, Michelle M. Lau, Niansheng Chu, Edward M. Behrens

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CXCL9 inhibition does not ameliorate disease in murine models of both primary and secondary hemophagocytic lymphohistiocytosis by Tamir Diamond, Michelle Lau, Jeremy Morrissette, Niansheng Chu, Edward M. Behrens

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Effector memory CD8 T-cells as a novel peripheral blood biomarker for activated T-cell pediatric acute liver failure. by Catherine A Chapin, Thomas M Burn, Tamir Diamond, Kathleen M Loomes, Estella M Alonso, Edward M Behrens

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Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay. by Mobin A Karimi, Eric Lee, Michael H Bachmann, Ana Maria Salicioni, Edward M Behrens, Taku Kambayashi, Cynthia L Baldwin

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Familial hemophagocytic lymphohistiocytosis hepatitis is mediated by IFN-γ in a predominantly hepatic-intrinsic manner. by Tamir Diamond, Thomas N Burn, Mailyn A Nishiguchi, Danielle Minichino, Julie Chase, Niansheng Chu, Portia A Kreiger, Edward M Behrens

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Familial hemophagocytic lymphohistiocytosis hepatitis is mediated by IFN-γ in a predominantly hepatic-intrinsic manner by Tamir Diamond, Thomas N. Burn, Mailyn A. Nishiguchi, Danielle Minichino, Julie Chase, Niansheng Chu, Portia A. Kreiger, Edward M. Behrens

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Skewed Cytokine Responses Rather Than the Magnitude of the Cytokine Storm May Drive Cardiac Dysfunction in Multisystem Inflammatory Syndrome in Children by Joyce C. Chang, Daisuke Matsubara, Ryan W. Morgan, Caroline Diorio, Sumekala Nadaraj, David T. Teachey, Hamid Bassiri, Edward M. Behrens, Anirban Banerjee

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Avoid a rash diagnosis: reconsidering cytophagic histiocytic panniculitis as a distinct clinical-pathologic entity by Jessica Perfetto, MD, Edward M. Behrens, MD, Melissa A. Lerman, MD, PhD, MSCE, Michele E. Paessler, DO, Emily J. Liebling, MD

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Tyrosine 870 of TLR9 is critical for receptor maturation rather than phosphorylation-dependent ligand-induced signaling. by Chhanda Biswas, Sheila Rao, Katharine Slade, David Hyman, Devin Dersh, Adriana R Mantegazza, Philip W Zoltick, Michael S Marks, Yair Argon, Edward M Behrens

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Transcriptional Analysis of Liver Tissue Identifies Distinct Phenotypes of Indeterminate Pediatric Acute Liver Failure by Catherine A Chapin, Sarah A Taylor, Padmini Malladi, Katie Neighbors, Hector Melin‐Aldana, Portia A Kreiger, Nina Bowsher, Matthew J Schipma, Kathleen M Loomes, Edward M Behrens, Estella M Alonso

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Low-dose biliatresone treatment of pregnant mice causes subclinical biliary disease in their offspring: Evidence for a spectrum of neonatal injury. by Kapish Gupta, Jimmy P Xu, Tamir Diamond, Iris E M de Jong, Andrew Glass, Jessica Llewellyn, Neil D Theise, Orith Waisbourd-Zinman, Jeffrey D Winkler, Edward M Behrens, Clementina Mesaros, Rebecca G Wells

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Kagami Ogata syndrome: a small deletion refines critical region for imprinting by Gonench Kilich, Kelly Hassey, Edward M. Behrens, Marni Falk, Adeline Vanderver, Daniel J. Rader, Patrick J. Cahill, Anna Raper, Zhe Zhang, Dawn Westerfer, Tanaya Jadhav, Laura Conlin, Kosuke Izumi, Ramakrishnan Rajagopalan, Kathleen E. Sullivan, UDN Consortium

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c-Myc uses Cul4b to preserve genome integrity and promote antiviral CD8+ T cell immunity by Asif A. Dar, Dale D. Kim, Scott M. Gordon, Kathleen Klinzing, Siera Rosen, Ipsita Guha, Nadia Porter, Yohaniz Ortega, Katherine S. Forsyth, Jennifer Roof, Hossein Fazelinia, Lynn A. Spruce, Laurence C. Eisenlohr, Edward M. Behrens, Paula M. Oliver

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Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction by Caroline Diorio, Rawan Shraim, Laura A. Vella, Josephine R. Giles, Amy E. Baxter, Derek A. Oldridge, Scott W. Canna, Sarah E. Henrickson, Kevin O. McNerney, Frances Balamuth, Chakkapong Burudpakdee, Jessica Lee, Tomas Leng, Alvin Farrel, Michele P. Lambert, Kathleen E. Sullivan, E. John Wherry, David T. Teachey, Hamid Bassiri, Edward M. Behrens

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