Edward W. Yu

Edward W. Yu is an American crystallographer.

After completing his doctoral degree at the University of Michigan in 1997, Yu became a postdoctoral researcher with the National Institutes of Health, then subsequently joined the faculty of Iowa State University in 2004. He is also associated with the Ames National Laboratory. ISU's Department of Chemistry named Yu to the John D. Corbett Professorship in 2014. That year, he was also elected a fellow of the American Association for the Advancement of Science. In 2016, the American Physical Society elected Yu to fellowship, "[f]or his distinguished contributions to the field of efflux transporters, which mediate resistance to a variety of antimicrobials in bacteria, and his research into the crystallography of integral membrane proteins." Provided by Wikipedia
Showing 1 - 20 results of 25 for search 'Edward W. Yu', query time: 4.06s Refine Results
  1. 1
    Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity

    Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity by Zhemin Zhang, Christopher E. Morgan, Meng Cui, Edward W. Yu

    Published 2023-02-01
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  2. 2
    An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii

    An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii by Christopher E. Morgan, Zhemin Zhang, Robert A. Bonomo, Edward W. Yu

    Published 2022-02-01
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  3. 3
    Cryo-EM Structures of the Klebsiella pneumoniae AcrB Multidrug Efflux Pump

    Cryo-EM Structures of the Klebsiella pneumoniae AcrB Multidrug Efflux Pump by Zhemin Zhang, Christopher E. Morgan, Robert A. Bonomo, Edward W. Yu

    Published 2023-06-01
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  4. 4
    Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator

    Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator by Zhemin Zhang, Yuqi Yan, Jinji Pang, Lei Dai, Qijing Zhang, Edward W. Yu

    Published 2024-03-01
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  5. 5
    Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance

    Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance by Zhemin Zhang, Nicholas Lizer, Zuowei Wu, Christopher E. Morgan, Yuqi Yan, Qijing Zhang, Edward W. Yu

    Published 2023-08-01
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  6. 6
    Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump

    Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump by Meinan Lyu, Julio C. Ayala, Isabella Chirakos, Chih-Chia Su, William M. Shafer, Edward W. Yu

    Published 2022-10-01
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  7. 7
    Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport.

    Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport. by Chih-Chia Su, Philip A Klenotic, Meng Cui, Meinan Lyu, Christopher E Morgan, Edward W Yu

    Published 2021-08-01
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  8. 8
    High-resolution structural-omics of human liver enzymes

    High-resolution structural-omics of human liver enzymes by Chih-Chia Su, Meinan Lyu, Zhemin Zhang, Masaru Miyagi, Wei Huang, Derek J. Taylor, Edward W. Yu

    Published 2023-06-01
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  9. 9
    (S)-5-ethynyl-anabasine, a novel compound, is a more potent agonist than other nicotine alkaloids on the nematode Asu-ACR-16 receptor

    (S)-5-ethynyl-anabasine, a novel compound, is a more potent agonist than other nicotine alkaloids on the nematode Asu-ACR-16 receptor by Fudan Zheng, Xiangwei Du, Tsung-Han Chou, Alan P. Robertson, Edward W. Yu, Brett VanVeller, Richard J. Martin

    Published 2017-04-01
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  10. 10
    Mapping Protein–Protein Interactions at Birth: Single-Particle Cryo-EM Analysis of a Ribosome–Nascent Globin Complex

    Mapping Protein–Protein Interactions at Birth: Single-Particle Cryo-EM Analysis of a Ribosome–Nascent Globin Complex by Meranda M. Masse, Rachel B. Hutchinson, Christopher E. Morgan, Heather J. Allaman, Hongqing Guan, Edward W. Yu, Silvia Cavagnero

    Published 2024-02-01
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  11. 11
    Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates

    Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates by Christopher E. Morgan, Przemyslaw Glaza, Inga V. Leus, Anhthu Trinh, Chih-Chia Su, Meng Cui, Helen I. Zgurskaya, Edward W. Yu

    Published 2021-02-01
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  12. 12
    Cryo-EM Structures of CusA Reveal a Mechanism of Metal-Ion Export

    Cryo-EM Structures of CusA Reveal a Mechanism of Metal-Ion Export by Mitchell A. Moseng, Meinan Lyu, Tanadet Pipatpolkai, Przemyslaw Glaza, Corey C. Emerson, Phoebe L. Stewart, Phillip J. Stansfeld, Edward W. Yu

    Published 2021-04-01
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  13. 13
    Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance

    Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance by Meinan Lyu, Mitchell A. Moseng, Jennifer L. Reimche, Concerta L. Holley, Vijaya Dhulipala, Chih-Chia Su, William M. Shafer, Edward W. Yu

    Published 2020-06-01
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  14. 14
    Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment

    Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment by Samual C. Allgood, Chih-Chia Su, Amy L. Crooks, Christian T. Meyer, Bojun Zhou, Meredith D. Betterton, Michael R. Barbachyn, Edward W. Yu, Corrella S. Detweiler

    Published 2023-12-01
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  15. 15
    A cell-based infection assay identifies efflux pump modulators that reduce bacterial intracellular load.

    A cell-based infection assay identifies efflux pump modulators that reduce bacterial intracellular load. by Abigail L Reens, Amy L Crooks, Chih-Chia Su, Toni A Nagy, David L Reens, Jessica D Podoll, Madeline E Edwards, Edward W Yu, Corrella S Detweiler

    Published 2018-06-01
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  16. 16
    Structure and Function of Neisseria gonorrhoeae MtrF Illuminates a Class of Antimetabolite Efflux Pumps

    Structure and Function of Neisseria gonorrhoeae MtrF Illuminates a Class of Antimetabolite Efflux Pumps by Chih-Chia Su, Jani Reddy Bolla, Nitin Kumar, Abhijith Radhakrishnan, Feng Long, Jared A. Delmar, Tsung-Han Chou, Kanagalaghatta R. Rajashankar, William M. Shafer, Edward W. Yu

    Published 2015-04-01
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  17. 17
    A small molecule that mitigates bacterial infection disrupts Gram-negative cell membranes and is inhibited by cholesterol and neutral lipids.

    A small molecule that mitigates bacterial infection disrupts Gram-negative cell membranes and is inhibited by cholesterol and neutral lipids. by Jamie L Dombach, Joaquin L J Quintana, Toni A Nagy, Chun Wan, Amy L Crooks, Haijia Yu, Chih-Chia Su, Edward W Yu, Jingshi Shen, Corrella S Detweiler

    Published 2020-12-01
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  18. 18
    Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1

    Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1 by Kristy Rochon, Brianna L. Bauer, Nathaniel A. Roethler, Yuli Buckley, Chih-Chia Su, Wei Huang, Rajesh Ramachandran, Maria S. K. Stoll, Edward W. Yu, Derek J. Taylor, Jason A. Mears

    Published 2024-02-01
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  19. 19
    Cryo-Electron Microscopy Structure of an <named-content content-type="genus-species">Acinetobacter baumannii</named-content> Multidrug Efflux Pump

    Cryo-Electron Microscopy Structure of an <named-content content-type="genus-species">Acinetobacter baumannii</named-content> Multidrug Efflux Pump by Chih-Chia Su, Christopher E. Morgan, Sekhar Kambakam, Malligarjunan Rajavel, Harry Scott, Wei Huang, Corey C. Emerson, Derek J. Taylor, Phoebe L. Stewart, Robert A. Bonomo, Edward W. Yu

    Published 2019-08-01
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  20. 20
    RND Pump-Mediated Efflux of Amotosalen, a Compound Used in Pathogen Inactivation Technology to Enhance Safety of Blood Transfusion Products, May Compromise Its Gram-Negative Anti-Bacterial Activity

    RND Pump-Mediated Efflux of Amotosalen, a Compound Used in Pathogen Inactivation Technology to Enhance Safety of Blood Transfusion Products, May Compromise Its Gram-Negative Anti-B... by Alex B. Green, Lucius Chiaraviglio, Katherine A. Truelson, Katelyn E. Zulauf, Meng Cui, Zhemin Zhang, Matthew P. Ware, Willy A. Flegel, Richard L. Haspel, Edward W. Yu, James E. Kirby

    Published 2023-04-01
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