Edwin Chapman (biochemist)

Edwin R. Chapman (born July 20, 1962 in Bellingham, Washington) is an American biochemist known for his work on Ca2+-triggered exocytosis. He currently serves as the Ricardo Miledi Professor of Neuroscience at the University of Wisconsin–Madison, where he is also an investigator of the Howard Hughes Medical Institute (HHMI). Provided by Wikipedia
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  1. 1
    Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons

    Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons by Jason D Vevea, Edwin R Chapman

    Published 2020-06-01
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  2. 2
    "Self" versus "non-self" connectivity dictates properties of synaptic transmission and plasticity.

    "Self" versus "non-self" connectivity dictates properties of synaptic transmission and plasticity. by Huisheng Liu, Edwin R Chapman, Camin Dean

    Published 2013-01-01
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  3. 3
    Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin

    Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin by Nicholas A. Courtney, Huan Bao, Joseph S. Briguglio, Edwin R. Chapman

    Published 2019-09-01
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  4. 4
    The juxtamembrane linker of synaptotagmin 1 regulates Ca2+ binding via liquid-liquid phase separation

    The juxtamembrane linker of synaptotagmin 1 regulates Ca2+ binding via liquid-liquid phase separation by Nikunj Mehta, Sayantan Mondal, Emma T. Watson, Qiang Cui, Edwin R. Chapman

    Published 2024-01-01
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  5. 5
    Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores

    Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores by Debasis Das, Huan Bao, Kevin C. Courtney, Lanxi Wu, Edwin R. Chapman

    Published 2020-01-01
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  6. 6
    Functionalization and higher-order organization of liposomes with DNA nanostructures

    Functionalization and higher-order organization of liposomes with DNA nanostructures by Zhao Zhang, Zhaomeng Feng, Xiaowei Zhao, Dominique Jean, Zhiheng Yu, Edwin R. Chapman

    Published 2023-08-01
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  7. 7
    Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons

    Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons by Emma T Watson, Michaela M Pauers, Michael J Seibert, Jason D Vevea, Edwin R Chapman

    Published 2023-02-01
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  8. 8
    Digital nanoreactors to control absolute stoichiometry and spatiotemporal behavior of DNA receptors within lipid bilayers

    Digital nanoreactors to control absolute stoichiometry and spatiotemporal behavior of DNA receptors within lipid bilayers by Vishal Maingi, Zhao Zhang, Chris Thachuk, Namita Sarraf, Edwin R. Chapman, Paul W. K. Rothemund

    Published 2023-03-01
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  9. 9
    Different states of synaptotagmin regulate evoked versus spontaneous release

    Different states of synaptotagmin regulate evoked versus spontaneous release by Hua Bai, Renhao Xue, Huan Bao, Leili Zhang, Arun Yethiraj, Qiang Cui, Edwin R. Chapman

    Published 2016-03-01
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  10. 10
    N-glycoproteomics of brain synapses and synaptic vesicles

    N-glycoproteomics of brain synapses and synaptic vesicles by Mazdak M. Bradberry, Trenton M. Peters-Clarke, Evgenia Shishkova, Edwin R. Chapman, Joshua J. Coon

    Published 2023-04-01
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  11. 11
    Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

    Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons by Jason D Vevea, Grant F Kusick, Kevin C Courtney, Erin Chen, Shigeki Watanabe, Edwin R Chapman

    Published 2021-09-01
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  12. 12
    Synaptotagmin-7 outperforms synaptotagmin-1 to promote the formation of large, stable fusion pores via robust membrane penetration

    Synaptotagmin-7 outperforms synaptotagmin-1 to promote the formation of large, stable fusion pores via robust membrane penetration by Kevin C. Courtney, Taraknath Mandal, Nikunj Mehta, Lanxi Wu, Yueqi Li, Debasis Das, Qiang Cui, Edwin R. Chapman

    Published 2023-11-01
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  13. 13
    SV2 mediates entry of tetanus neurotoxin into central neurons.

    SV2 mediates entry of tetanus neurotoxin into central neurons. by Felix L Yeh, Min Dong, Jun Yao, William H Tepp, Guangyun Lin, Eric A Johnson, Edwin R Chapman

    Published 2010-11-01
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  14. 14
    Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment

    Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment by Huisheng Liu, Hua Bai, Enfu Hui, Lu Yang, Chantell S Evans, Zhao Wang, Sung E Kwon, Edwin R Chapman

    Published 2014-02-01
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  15. 15
    Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release

    Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release by Zhenyong Wu, Grant F Kusick, Manon MM Berns, Sumana Raychaudhuri, Kie Itoh, Alexander M Walter, Edwin R Chapman, Shigeki Watanabe

    Published 2024-03-01
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  16. 16
    Deterministic HOX Patterning in Human Pluripotent Stem Cell-Derived Neuroectoderm

    Deterministic HOX Patterning in Human Pluripotent Stem Cell-Derived Neuroectoderm by Ethan S. Lippmann, Clay E. Williams, David A. Ruhl, Maria C. Estevez-Silva, Edwin R. Chapman, Joshua J. Coon, Randolph S. Ashton

    Published 2015-04-01
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  17. 17
    Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity

    Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity by Derrick P. McVicker, Adam M. Awe, Karl E. Richters, Rebecca L. Wilson, Diana A. Cowdrey, Xindao Hu, Edwin R. Chapman, Erik W. Dent

    Published 2016-09-01
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  18. 18
    Interneuronal Transfer and Distal Action of Tetanus Toxin and Botulinum Neurotoxins A and D in Central Neurons

    Interneuronal Transfer and Distal Action of Tetanus Toxin and Botulinum Neurotoxins A and D in Central Neurons by Ewa Bomba-Warczak, Jason D. Vevea, Joel M. Brittain, Annette Figueroa-Bernier, William H. Tepp, Eric A. Johnson, Felix L. Yeh, Edwin R. Chapman

    Published 2016-08-01
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  19. 19
    The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission

    The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission by Berrak Ugur, Huan Bao, Michal Stawarski, Lita R. Duraine, Zhongyuan Zuo, Yong Qi Lin, G. Gregory Neely, Gregory T. Macleod, Edwin R. Chapman, Hugo J. Bellen

    Published 2017-12-01
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  20. 20
    Inappropriate Intrusion of an Axonal Mitochondrial Anchor into Dendrites Causes Neurodegeneration

    Inappropriate Intrusion of an Axonal Mitochondrial Anchor into Dendrites Causes Neurodegeneration by Dinesh C. Joshi, Chuan-Li Zhang, Lavanya Babujee, Jason D. Vevea, Benjamin K. August, Zu-Hang Sheng, Edwin R. Chapman, Timothy M. Gomez, Shing Yan Chiu

    Published 2019-10-01
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