The Immuno-Modulatory Effects of Inhibitor of Apoptosis Protein Antagonists in Cancer Immunotherapy ‌ Jessica Michie, Conor J. Kearney, Edwin D. Hawkins, John Silke, Jane Oliaro

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Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny ‌ Mark R. Dowling, Mark R. Dowling, Andrey Kan, Andrey Kan, Susanne Heinzel, Susanne Heinzel, Julia M. Marchingo, Julia M. Marchingo, Philip D. Hodgkin, Philip D. Hodgkin, Edwin D. Hawkins, Edwin D. Hawkins

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An arrayed CRISPR screen of primary B cells reveals the essential elements of the antibody secretion pathway ‌ Stephanie Trezise, Stephanie Trezise, Stephanie Trezise, Isabella Y. Kong, Isabella Y. Kong, Isabella Y. Kong, Edwin D. Hawkins, Edwin D. Hawkins, Marco J. Herold, Marco J. Herold, Simon N. Willis, Simon N. Willis, Stephen L. Nutt, Stephen L. Nutt

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Cyton2: A Model of Immune Cell Population Dynamics That Includes Familial Instructional Inheritance ‌ HoChan Cheon, Andrey Kan, Andrey Kan, Giulio Prevedello, Simone C. Oostindie, Simone C. Oostindie, Simon J. Dovedi, Edwin D. Hawkins, Edwin D. Hawkins, Julia M. Marchingo, Susanne Heinzel, Susanne Heinzel, Ken R. Duffy, Philip D. Hodgkin, Philip D. Hodgkin

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Automated Identification and Localization of Hematopoietic Stem Cells in 3D Intravital Microscopy Data ‌ Reema A. Khorshed, Edwin D. Hawkins, Delfim Duarte, Mark K. Scott, Olufolake A. Akinduro, Narges M. Rashidi, Martin Spitaler, Cristina Lo Celso

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The passive biomechanics of human pelvic collecting lymphatic vessels. ‌ Dimitrios Athanasiou, Lowell T Edgar, Mohammad Jafarnejad, Katherine Nixon, Delfim Duarte, Edwin D Hawkins, Samira Jamalian, Paula Cunnea, Cristina Lo Celso, Shunichi Kobayashi, Christina Fotopoulou, James E Moore

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Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia. ‌ Edwin D Hawkins, Jane Oliaro, Kelly M Ramsbottom, Stephen B Ting, Faruk Sacirbegovic, Michael Harvey, Tanja Kinwell, Jacques Ghysdael, Ricky W Johnstone, Patrick O Humbert, Sarah M Russell

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Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis ‌ Raymond K. H. Yip, Joel S. Rimes, Bianca D. Capaldo, François Vaillant, Kellie A. Mouchemore, Bhupinder Pal, Yunshun Chen, Elliot Surgenor, Andrew J. Murphy, Robin L. Anderson, Gordon K. Smyth, Geoffrey J. Lindeman, Edwin D. Hawkins, Jane E. Visvader

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MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions ‌ Shene Chiou, Wayne Cawthorne, Thomas Soerianto, Vinzenz Hofferek, Komal M. Patel, Sarah E. Garnish, Emma C. Tovey Crutchfield, Cathrine Hall, Joanne M. Hildebrand, Malcolm J. McConville, Kate E. Lawlor, Edwin D. Hawkins, Andre L. Samson, James M. Murphy

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Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene ‌ Marcus Lefebure, Richard W. Tothill, Elizabeth Kruse, Edwin D. Hawkins, Jake Shortt, Geoffrey M. Matthews, Gareth P. Gregory, Benjamin P. Martin, Madison J. Kelly, Izabela Todorovski, Maria A. Doyle, Richard Lupat, Jason Li, Jan Schroeder, Meaghan Wall, Stuart Craig, Gretchen Poortinga, Don Cameron, Megan Bywater, Lev Kats, Micah D. Gearhart, Vivian J. Bardwell, Ross A. Dickins, Ross D. Hannan, Anthony T. Papenfuss, Ricky W. Johnstone

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MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis ‌ Andre L. Samson, Ying Zhang, Niall D. Geoghegan, Xavier J. Gavin, Katherine A. Davies, Michael J. Mlodzianoski, Lachlan W. Whitehead, Daniel Frank, Sarah E. Garnish, Cheree Fitzgibbon, Anne Hempel, Samuel N. Young, Annette V. Jacobsen, Wayne Cawthorne, Emma J. Petrie, Maree C. Faux, Kristy Shield-Artin, Najoua Lalaoui, Joanne M. Hildebrand, John Silke, Kelly L. Rogers, Guillaume Lessene, Edwin D. Hawkins, James M. Murphy

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In situ visualization of endothelial cell-derived extracellular vesicle formation in steady state and malignant conditions ‌ Georgia K. Atkin-Smith, Jascinta P. Santavanond, Amanda Light, Joel S. Rimes, Andre L. Samson, Jeremy Er, Joy Liu, Darryl N. Johnson, Mélanie Le Page, Pradeep Rajasekhar, Raymond K. H. Yip, Niall D. Geoghegan, Kelly L. Rogers, Catherine Chang, Vanessa L. Bryant, Mai Margetts, M. Cristina Keightley, Trevor J. Kilpatrick, Michele D. Binder, Sharon Tran, Erinna F. Lee, Walter D. Fairlie, Dilara C. Ozkocak, Andrew H. Wei, Edwin D. Hawkins, Ivan K. H. Poon

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An immunohistochemical atlas of necroptotic pathway expression ‌ Shene Chiou, Aysha H Al-Ani, Yi Pan, Komal M Patel, Isabella Y Kong, Lachlan W Whitehead, Amanda Light, Samuel N Young, Marilou Barrios, Callum Sargeant, Pradeep Rajasekhar, Leah Zhu, Anne Hempel, Ann Lin, James A Rickard, Cathrine Hall, Pradnya Gangatirkar, Raymond KH Yip, Wayne Cawthorne, Annette V Jacobsen, Christopher R Horne, Katherine R Martin, Lisa J Ioannidis, Diana S Hansen, Jessica Day, Ian P Wicks, Charity Law, Matthew E Ritchie, Rory Bowden, Joanne M Hildebrand, Lorraine A O’Reilly, John Silke, Lisa Giulino-Roth, Ellen Tsui, Kelly L Rogers, Edwin D Hawkins, Britt Christensen, James M Murphy, André L Samson

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