A triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor (DSM421) with improved drug-like properties for treatment and prevention of malaria by Phillips, M, White, K, Kokkonda, S, Deng, X, White, J, El Mazouni, F, Marsh, K, Tomchick, D, Manjalanagara, K, Rudra, K, Wirjanata, G, Noviyanti, R, Price, R, Marfurt, J, Shackleford, D, Chiu, F, Campbell, M, Jimenez Diaz, M, Ferrer-Bazaga, S, Angulo-Barturen, I, Martínez-Martínez, M, Lafuente-Monasterio, M, Kaminsky, W, Silue, K, Zeeman, A, Kocken, C, Leroy, D, Blasco, B, Rossignol, E, Rueckle, T, Matthews, D, Burrows, J, Waterson, D, Palmer, M, Rathod, P, Charman, S

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria by Phillips, M. A., Lotharius, J., Marsh, K., White, J., Dayan, A., White, K. L., Njoroge, J. W., El Mazouni, F., Lao, Y., Kokkonda, S., Tomchick, D. R., Deng, X., Laird, T., Ng, C. L., Fidock, D. A., Wittlin, S., Lafuente-Monasterio, M., Benito, F. J. G., Alonso, L. M. S., Martinez, M. S., Jimenez-Diaz, M. B., Bazaga, S. F., Angulo-Barturen, I., Haselden, J. N., Louttit, J., Cui, Y., Sridhar, A., Zeeman, A.-M., Kocken, C., Sauerwein, R., Dechering, K., Avery, V. M., Duffy, S., Delves, M., Sinden, R., Ruecker, A., Wickham, K. S., Rochford, R., Gahagen, J., Iyer, L., Riccio, E., Mirsalis, J., Bathhurst, I., Rueckle, T., Ding, X., Campo, B., Leroy, D., Rogers, M. J., Rathod, P. K., Burrows, J. N., Charman, S. A., Bhatia, Sangeeta N, March-Riera, Sandra

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