A single-arm study design with non-inferiority and superiority time-to-event endpoints: a tool for proof-of-concept and de-intensification strategies in breast cancer by Miguel Sampayo-Cordero, Bernat Miguel-Huguet, Andrea Malfettone, Elena López-Miranda, Elena López-Miranda, María Gion, Elena Abad, Daniel Alcalá-López, Jhudit Pérez-Escuredo, José Manuel Pérez-García, José Manuel Pérez-García, Antonio Llombart-Cussac, Antonio Llombart-Cussac, Javier Cortés, Javier Cortés, Javier Cortés

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High Frequency of ERBB2 Activating Mutations in Invasive Lobular Breast Carcinoma with Pleomorphic Features by Juan Manuel Rosa-Rosa, Tamara Caniego-Casas, Susanna Leskela, Eva Cristobal, Silvia González-Martínez, Esther Moreno-Moreno, Elena López-Miranda, Esther Holgado, Belén Pérez-Mies, Pilar Garrido, José Palacios

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Maintained complete response to talazoparib in a BRCA-2 mutated metastatic luminal breast cancer: case report and review of literature by Víctor Albarrán, Jesús Chamorro, Javier Pozas, María San Román, Diana Isabel Rosero, Cristina Saavedra, María Gion, Alfonso Cortés, Elena Escalera, Eva Guerra, Elena López Miranda, María Fernández Abad, Noelia Martínez Jañez

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Inclusion of non-inferiority analysis in superiority-based clinical trials with single-arm, two-stage Simon's design by Miguel Sampayo-Cordero, Bernat Miguel-Huguet, José Pérez-García, David Páez, Ángel L. Guerrero-Zotano, Javier Garde-Noguera, Elena Aguirre, Esther Holgado, Elena López-Miranda, Xin Huang, Andrea Malfettone, Antonio Llombart-Cussac, Javier Cortés

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Discordant Humoral and T-Cell Response to mRNA SARS-CoV-2 Vaccine and the Risk of Breakthrough Infections in Women with Breast Cancer, Receiving Cyclin-Dependent Kinase 4 and 6 Inh... by Cristina Saavedra, Alejandro Vallejo, Federico Longo, Juan José Serrano, María Fernández, María Gion, Elena López-Miranda, Noelia Martínez-Jáñez, Eva Guerra, Jesús Chamorro, Diana Rosero, Héctor Velasco, Adrián Martín, Alfredo Carrato, José Luis Casado, Alfonso Cortés

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Trastuzumab Emtansine Plus Non-Pegylated Liposomal Doxorubicin in HER2-Positive Metastatic Breast Cancer (Thelma): A Single-Arm, Multicenter, Phase Ib Trial by Elena López-Miranda, José Manuel Pérez-García, Serena Di Cosimo, Etienne Brain, Maja Ravnik, Santiago Escrivá-de-Romaní, Maria Vidal, Joseph Gligorov, Simona Borštnar, Laura Calabuig, Miguel Sampayo-Cordero, Andrea Malfettone, Antonio Llombart-Cussac, Thomas M. Suter, Javier Cortés

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Challenging Endocrine Sensitivity of Hormone Receptor-Positive/HER2-Negative Advanced Breast Cancer with the Combination of Eribulin and Endocrine Therapy: The REVERT Study by Ana López González, Sonia Del Barco Berrón, Isabel Grau, Maria Galan, Beatriz Castelo Fernández, Alfonso Cortés, Pedro Sánchez Rovira, Alejandro Martinez-Bueno, Xavier Gonzalez, Almudena García, Petra Gener, Leonardo Mina, Daniel Alcalá-López, Miguel Sampayo, Javier Cortés, José Manuel Pérez-Garcia, Antonio Llombart-Cussac, Elena López-Miranda

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Pembrolizumab Plus Gemcitabine in the Subset of Triple-Negative Advanced Breast Cancer Patients in the GEICAM/2015-04 (PANGEA-Breast) Study by Luis de la Cruz-Merino, María Gion, Josefina Cruz-Jurado, Vanesa Quiroga, Raquel Andrés, Fernando Moreno, Jose L. Alonso-Romero, Manuel Ramos, Esther Holgado, Javier Cortés, Elena López-Miranda, Fernando Henao-Carrasco, Natalia Palazón-Carrión, Luz M. Rodríguez, Isaac Ceballos, Maribel Casas, Sara Benito, Massimo Chiesa, Susana Bezares, Rosalia Caballero, Carlos Jiménez-Cortegana, Víctor Sánchez-Margalet, Federico Rojo

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