To inhibit TrxR1 is to inactivate STAT3–Inhibition of TrxR1 enzymatic function by STAT3 small molecule inhibitors by Sander Busker, Brent Page, Elias S.J. Arnér

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Qualitative Differences in Protection of PTP1B Activity by the Reductive Trx1 or TRP14 Enzyme Systems upon Oxidative Challenges with Polysulfides or H₂O₂ Toge... by Markus Dagnell, Qing Cheng, Elias S.J. Arnér

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Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells. by Karin Anestål, Stefanie Prast-Nielsen, Narimantas Cenas, Elias S J Arnér

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Time- and cell-resolved dynamics of redox-sensitive Nrf2, HIF and NF-κB activities in 3D spheroids enriched for cancer stem cells by Anna P. Kipp, Stefanie Deubel, Elias S.J. Arnér, Katarina Johansson

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Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin by Pierre Sabatier, Christian M. Beusch, Radosveta Gencheva, Qing Cheng, Roman Zubarev, Elias S.J. Arnér

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Novel gold(III)-dithiocarbamate complex targeting bacterial thioredoxin reductase: antimicrobial activity, synergy, toxicity, and mechanistic insights by Carlos Ratia, Victoria Ballén, Yaiza Gabasa, Raquel G. Soengas, María Velasco-de Andrés, María José Iglesias, Qing Cheng, Francisco Lozano, Francisco Lozano, Francisco Lozano, Elias S. J. Arnér, Elias S. J. Arnér, Fernando López-Ortiz, Sara M. Soto, Sara M. Soto

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Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress by Andreas Lundqvist, Rolf Kiessling, Isabelle Magalhaes, Jonas Mattsson, Stefanie Renken, Takahiro Nakajima, Elias S J Arnér, Stina Linnea Wickström

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TXNL1 has dual functions as a redox active thioredoxin-like protein as well as an ATP- and redox-independent chaperone by Attila Andor, Mahendravarman Mohanraj, Zsuzsanna Anna Pató, Katalin Úri, Beáta Biri-Kovács, Qing Cheng, Elias S.J. Arnér

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Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target. by Angela N Kuntz, Elisabeth Davioud-Charvet, Ahmed A Sayed, Lindsay L Califf, Jean Dessolin, Elias S J Arnér, David L Williams

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Correction: Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target. by Angela N Kuntz, Elisabeth Davioud-Charvet, Ahmed A Sayed, Lindsay L Califf, Jean Dessolin, Elias S. J Arnér, David L Williams

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Evaluation of dithiothreitol-oxidizing capacity (DOC) as a serum biomarker for chronic hepatitis B in patients exhibiting normal alanine aminotransferase levels: a pilot study towa... by Lumin Yang, Yafei Zhang, Ke Zhang, Zhongping Liu, Tengfei He, Xiaowei Zheng, Lei Li, Elias S J Arnér, Zhenhua Zhang, Jinsong Zhang

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Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4 by Dorian M. Cheff, Qing Cheng, Hui Guo, Jameson Travers, Carleen Klumpp-Thomas, Min Shen, Elias S.J. Arnér, Matthew D. Hall

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The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1 by Dorian M. Cheff, Chuying Huang, Karoline C. Scholzen, Radosveta Gencheva, Michael H. Ronzetti, Qing Cheng, Matthew D. Hall, Elias S.J. Arnér

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Identification and targeting of selective vulnerability rendered by tamoxifen resistance by Madhurendra Singh, Xiaolei Zhou, Xinsong Chen, Gema Sanz Santos, Sylvain Peuget, Qing Cheng, Ali Rihani, Elias S. J. Arnér, Johan Hartman, Galina Selivanova

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Clozapine suppresses NADPH oxidase activation, counteracts cytosolic H2O2, and triggers early onset mitochondrial dysfunction during adipogenesis of human liposarcoma SW872 cells by Giulia Blandino, Mara Fiorani, Barbara Canonico, Rita De Matteis, Andrea Guidarelli, Mariele Montanari, Gloria Buffi, Lucia Coppo, Elias S.J. Arnér, Orazio Cantoni

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Production and purification of homogenous recombinant human selenoproteins reveals a unique codon skipping event in E. coli and GPX4-specific affinity to bromosulfophthalein by Qing Cheng, Antonella Roveri, Giorgio Cozza, Luciana Bordin, Isabelle Rohn, Tanja Schwerdtle, Anna Kipp, Fulvio Ursini, Matilde Maiorino, Giovanni Miotto, Elias S.J. Arnér

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Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin by Amir Ata Saei, Hjalmar Gullberg, Pierre Sabatier, Christian M. Beusch, Katarina Johansson, Bo Lundgren, Per I. Arvidsson, Elias S.J. Arnér, Roman A. Zubarev

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Cardiolipin drives the catalytic activity of GPX4 on membranes: Insights from the R152H mutant by Antonella Roveri, Flavio Di Giacinto, Monica Rossetto, Giorgio Cozza, Qing Cheng, Giovanni Miotto, Lucio Zennaro, Maria Luisa Di Paolo, Elias S.J. Arnér, Marco De Spirito, Matilde Maiorino, Fulvio Ursini

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Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus by Francesca Fata, Radosveta Gencheva, Qing Cheng, Rachel Lullo, Matteo Ardini, Ilaria Silvestri, Federica Gabriele, Rodolfo Ippoliti, Christina A. Bulman, Judy A. Sakanari, David L. Williams, Elias S.J. Arnér, Francesco Angelucci

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Combining [11C]-AnxA5 PET imaging with serum biomarkers for improved detection in live mice of modest cell death in human solid tumor xenografts. by Qing Cheng, Li Lu, Jonas Grafström, Maria Hägg Olofsson, Jan-Olov Thorell, Erik Samén, Katarina Johansson, Hanna-Stina Ahlzén, Sharon Stone-Elander, Stig Linder, Elias S J Arnér, Sel-tag Imaging Project

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