SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity. by Derek Cerchione, Katherine Loveluck, Eric L Tillotson, Fred Harbinski, Jen DaSilva, Chase P Kelley, Elise Keston-Smith, Cecilia A Fernandez, Vic E Myer, Hariharan Jayaram, Barrett E Steinberg

Get full text

Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing by Colin McGaw, Anthony J. Garrity, Gabrielle Z. Munoz, Jeffrey R. Haswell, Sejuti Sengupta, Elise Keston-Smith, Pratyusha Hunnewell, Alexa Ornstein, Mishti Bose, Quinton Wessells, Noah Jakimo, Paul Yan, Huaibin Zhang, Lauren E. Alfonse, Roy Ziblat, Jason M. Carte, Wei-Cheng Lu, Derek Cerchione, Brendan Hilbert, Shanmugapriya Sothiselvam, Winston X. Yan, David R. Cheng, David A. Scott, Tia DiTommaso, Shaorong Chong

Get full text