Colorectal cancer in patients of advanced age is associated with increased incidence of BRAF p.V600E mutation and mismatch repair deficiency by Eric S. Christenson, Eric S. Christenson, Hua-Ling Tsai, Hua-Ling Tsai, Dung T. Le, Dung T. Le, Elizabeth M. Jaffee, Elizabeth M. Jaffee, Jonathan Dudley, Jonathan Dudley, Rena R. Xian, Rena R. Xian, Christopher D. Gocke, Christopher D. Gocke, James R. Eshleman, James R. Eshleman, Ming-Tseh Lin

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Analysis of Population Differences in Digital Conversations About Cancer Clinical Trials: Advanced Data Mining and Extraction Study by Edith A Perez, Elizabeth M Jaffee, John Whyte, Cheryl A Boyce, John D Carpten, Guillermina Lozano, Raymond M Williams, Karen M Winkfield, David Bernstein, Sung Poblete

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Solid Organ Transplantation Is Associated with an Increased Rate of Mismatch Repair Deficiency and PIK3CA Mutations in Colorectal Cancer by Eric S. Christenson, Valerie Lee, Hao Wang, Mark Yarchoan, Ana De Jesus-Acosta, Nilo Azad, Ahmet Gurakar, Ming-Tseh Lin, Dung T. Le, Daniel C. Brennan, Elizabeth M. Jaffee, Katherine Bever

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Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence by Shuming Zhang, Long Yuan, Ludmila Danilova, Guanglan Mo, Qingfeng Zhu, Atul Deshpande, Alexander T. F. Bell, Jennifer Elisseeff, Aleksander S. Popel, Robert A. Anders, Elizabeth M. Jaffee, Mark Yarchoan, Elana J. Fertig, Luciane T. Kagohara

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Integrated T cell cytometry metrics for immune-monitoring applications in immunotherapy clinical trials by Dimitrios N. Sidiropoulos, Genevieve L. Stein-O’Brien, Ludmila Danilova, Nicole E. Gross, Soren Charmsaz, Stephanie Xavier, James Leatherman, Hao Wang, Mark Yarchoan, Elizabeth M. Jaffee, Elana J. Fertig, Won Jin Ho

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Barcoding intracellular reverse transcription enables high-throughput phenotype-coupled T cell receptor analyses by Sahana Jayaraman, Janelle M. Montagne, Thomas R. Nirschl, Emily Marcisak, Jeanette Johnson, Amanda Huff, Meng-Hsuan Hsiao, Julie Nauroth, Thatcher Heumann, Jelani C. Zarif, Elizabeth M. Jaffee, Nilo Azad, Elana J. Fertig, Neeha Zaidi, H. Benjamin Larman

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641 A pilot study of a DNAJB1-PRKACA fusion kinase peptide vaccine combined with nivolumab and ipilimumab for patients with fibrolamellar hepatocellular carcinoma by Hao Wang, Paul Thomas, Elizabeth M Jaffee, Mark Yarchoan, Jennifer Durham, Brian Ladle, Alex Thompson, Madalena Brancati, Christopher Thoburn, Zeal Kamdar, Marina Baretti, Julie Nauroth, Anna Ferguson, Paige Griffith, Allison Kirk, Neeha Zaidi, Amanda Huff, Won Ho, Mark Furth

A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer by Mark Yarchoan, Chiung‐Yu Huang, Qingfeng Zhu, Anna K. Ferguson, Jennifer N. Durham, Robert A. Anders, Elizabeth D. Thompson, Noah S. Rozich, Dwayne L. Thomas II, Julie M. Nauroth, Christina Rodriguez, Arsen Osipov, Ana De Jesus‐Acosta, Dung T. Le, Adrian G. Murphy, Daniel Laheru, Ross C. Donehower, Elizabeth M. Jaffee, Lei Zheng, Nilofer S. Azad

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1245 Th17 and Type 2 CD8+ cytokine signatures predict irAEs in solid tumors by Evan J Lipson, Jarushka Naidoo, Julie Brahmer, Ludmila Danilova, Elizabeth M Jaffee, Won Jin Ho, Mark Yarchoan, Maximilian F Konig, Yasser Ged, Jean Hoffman-Censits, Jennifer Durham, Laura Cappelli, Sanjay Bansal, Aanika Balaji, Rajat Mohindra, Stephanie L Alden, Tanguy Y Seiwert, Chester J Kao, Soren Charmsaz, Madalena Brancati, Howard L Li, Kabeer Munjal, Hua-Ling Tsai, Alexei Hernandez, Nicole Gross, Erin M Coyne, Sarah M Shin, Brian Christmas, Christopher Thoburn, Marina Barretti, Rachel Garonce-Hediger, Laura Tang, G Scott Chandler

Molecular signature incorporating the immune microenvironment enhances thyroid cancer outcome prediction by George J. Xu, Matthew A. Loberg, Jean-Nicolas Gallant, Quanhu Sheng, Sheau-Chiann Chen, Brian D. Lehmann, Sophia M. Shaddy, Megan L. Tigue, Courtney J. Phifer, Li Wang, Mario W. Saab-Chalhoub, Lauren M. Dehan, Qiang Wei, Rui Chen, Bingshan Li, Christine Y. Kim, Donna C. Ferguson, James L. Netterville, Sarah L. Rohde, Carmen C. Solórzano, Lindsay A. Bischoff, Naira Baregamian, Aaron C. Shaver, Mitra Mehrad, Kim A. Ely, Daniel W. Byrne, Thomas P. Stricker, Barbara A. Murphy, Jennifer H. Choe, Luciane T. Kagohara, Elizabeth M. Jaffee, Eric C. Huang, Fei Ye, Ethan Lee, Vivian L. Weiss

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