Chemical probes for understudied kinases: challenges and opportunities by Serafim, RAM, Elkins, JM, Zuercher, WJ, Laufer, SA, Gehringer, M

Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer by Scott, F, Fala, AM, Pennicott, LE, Reuillon, TD, Massirer, KB, Elkins, JM, Ward, SE

Targeting the water network in cyclin G-associated kinase (GAK) with 4-anilino-quin(az)oline inhibitors by Asquith, CRM, Tizzard, GJ, Bennett, JM, Wells, CI, Elkins, JM, Willson, TM, Poso, A, Laitinen, T

Mining public domain data to develop selective DYRK1A inhibitors by Henderson, SH, Sorrell, F, Bennett, J, Hanley, MT, Robinson, S, Hopkins Navratilova, I, Elkins, JM, Ward, SE

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety by Sansook, S, Ocasio, CA, Day, IJ, Tizzard, GJ, Coles, SJ, Fedorov, O, Bennett, JM, Elkins, JM, Spencer, J

Discovery of a selective allosteric inhibitor targeting macrodomain 2 of polyadenosine-diphosphate-ribose polymerase 14 by Schuller, M, Riedel, K, Gibbs-Seymour, I, Uth, K, Sieg, C, Gehring, AP, Ahel, I, Bracher, F, Kessler, BM, Elkins, JM, Knapp, S

Discovery of a potent dual SLK/STK10 inhibitor based on a maleimide scaffold by Serafim, RAM, Sorrell, FJ, Berger, B-T, Collins, RJ, Vasconcelos, SNS, Massirer, KB, Knapp, S, Bennett, J, Fedorov, O, Patel, H, Zuercher, WJ, Elkins, JM

Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available... by Profeta, GS, Reis, CVD, Santiago, ADS, Godoi, PHC, Fala, AM, Wells, CI, Sartori, R, Salmazo, APT, Ramos, PZ, Massirer, KB, Elkins, JM, Drewry, DH, Gileadi, O, Couñago, RM

A ligand discovery toolbox for the WWE domain family of human E3 ligases by Münzker, L, Kimani, SW, Fowkes, MM, Dong, A, Zheng, H, Li, Y, Dasovich, M, Zak, KM, Leung, AKL, Elkins, JM, Kessler, D, Arrowsmith, CH, Halabelian, L, Böttcher, J

Discovery and characterization of selective and ligand-efficient DYRK inhibitors by Henderson, SH, Sorrell, F, Bennett, J, Fedorov, O, Hanley, MT, Godoi, PH, Ruela de Sousa, R, Robinson, S, Ashall-Kelly, A, Hopkins Navratilova, I, Walter, DS, Elkins, JM, Ward, SE

Synthesis and structure-activity relationships of 3,5-disubstituted-pyrrolo[2,3-b]pyridines as inhibitors of adaptor-sssociated kinase 1 with antiviral activity by Verdonck, S, Pu, S-Y, Sorrell, FJ, Elkins, JM, Froeyen, M, Gao, L-J, Prugar, LI, Dorosky, DE, Brannan, JM, Barouch-Bentov, R, Knapp, S, Dye, JM, Herdewijn, P, Einav, S, De Jonghe, S

Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2 by Berger, B-T, Amaral, M, Kokh, DB, Nunes-Alves, A, Musil, D, Heinrich, T, Schröder, M, Neil, R, Wang, J, Navratilova, I, Bomke, J, Elkins, JM, Müller, S, Frech, M, Wade, RC, Knapp, S

Updated protein domain annotation of the PARP protein family sheds new light on biological function by Suskiewicz, MJ, Munnur, D, Strømland, Ø, Yang, J-C, Easton, LE, Chatrin, C, Zhu, K, Baretić, D, Goffinont, S, Schuller, M, Wu, W-F, Elkins, JM, Ahel, D, Sanyal, S, Neuhaus, D, Ahel, I

Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist by Balıkçı, E, Marques, AMC, Bauer, LG, Seupel, R, Bennett, J, Raux, B, Buchan, K, Simelis, K, Singh, U, Rogers, C, Ward, J, Cheng, C, Szommer, T, Schützenhofer, K, Elkins, JM, Sloman, DL, Ahel, I, Fedorov, O, Brennan, PE, Huber, KVM

Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target by Alam, MM, Sanchez-Azqueta, A, Janha, O, Flannery, EL, Mahindra, A, Mapesa, K, Char, AB, Sriranganadane, D, Brancucci, NMB, Antonova-Koch, Y, Crouch, K, Simwela, NV, Millar, SB, Akinwale, J, Mitcheson, D, Solyakov, L, Dudek, K, Jones, C, Zapatero, C, Doerig, C, Nwakanma, DC, Vázquez, MJ, Colmenarejo, G, Lafuente-Monasterio, MJ, Leon, ML, Godoi, PHC, Elkins, JM, Waters, AP, Jamieson, AG, Álvaro, EF, Ranford-Cartwright, LC, Marti, M, Winzeler, EA, Gamo, FJ, Tobin, AB