The Therapeutic Challenge of Disseminated Bone Marrow Metastasis From HR-Positive HER2-Negative Breast Cancer: Case Report and Review of the Literature by Giovanna Garufi, Giovanna Garufi, Luisa Carbognin, Armando Orlandi, Antonella Palazzo, Giampaolo Tortora, Giampaolo Tortora, Emilio Bria, Emilio Bria

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Harnessing the epigenome to boost immunotherapy response in non-small cell lung cancer patients by Anastasios Gkountakos, Pietro Delfino, Rita T. Lawlor, Aldo Scarpa, Vincenzo Corbo, Emilio Bria

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Modern Challenges for Early-Phase Clinical Trial Design and Biomarker Discovery in Metastatic Non-Small-Cell Lung Cancer by Antonio Rossi, Sara Pilotto, Luisa Carbognin, Miriam Grazia Ferrara, Lorenzo Belluomini, Gennaro Daniele, Emilio Bria

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Seize the Opportunity With Small Tissue Samples: The Tailor Teaches! by Rocco Trisolini, MD, Emilio Bria, MD, Valeria Cetoretta, MD, Marta Viscuso, MD, Umberto Malapelle, MD

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Deciphering Crosstalk Circuits in Non-small Cell Lung Cancers with an Increasing Interval Length of Low Dose CT Screening by Rafael Rosell, Niki Karachaliou, Imane Chaib, Sara Pilotto, Emilio Bria, Juan Luis Fernández-Martínez, Jose Luis Ramirez

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Identification of Targetable Liabilities in the Dynamic Metabolic Profile of <i>EGFR</i>-Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance by Anastasios Gkountakos, Giovanni Centonze, Emanuele Vita, Lorenzo Belluomini, Michele Milella, Emilio Bria, Massimo Milione, Aldo Scarpa, Michele Simbolo

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The likelihood of being helped or harmed as a patient-centred tool to assess cyclin dependent kinase 4/6 inhibitors clinical impact and safety in metastatic breast cancer: a system... by Luca Mastrantoni, Armando Orlandi, Antonella Palazzo, Giovanna Garufi, Alessandra Fabi, Gennaro Daniele, Diana Giannarelli, Giampaolo Tortora, Emilio Bria

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Bronchoscopically-visible massive central airway cancer cavitation is associated with metastatic disease, lack of actionable mutations and poor prognosis: a case series by Daniele Magnini, Emilio Bria, Alessandra Cancellieri, Vanina Livi, Fausto Leoncini, Marco Ferrari, Teresa Bruni, Daniela Paioli, Rocco Trisolini

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Case report: Vitiligo-like toxicity due to ribociclib during first-line treatment of metastatic breast cancer: two cases of premature interruption of therapy and exceptional respon... by Mariangela Pasqualoni, Mariangela Pasqualoni, Armando Orlandi, Antonella Palazzo, Giovanna Garufi, Giovanna Garufi, Maria Chiara Cannizzaro, Maria Chiara Cannizzaro, Letizia Pontolillo, Letizia Pontolillo, Sergio Pannunzio, Sergio Pannunzio, Claudia Cutigni, Claudia Cutigni, Pietro Sollena, Francesco Federico, Emilio Bria, Emilio Bria, Giampaolo Tortora, Giampaolo Tortora

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The likelihood of being helped or harmed as a patient-centred tool to assess ALK-Inhibitors clinical impact and safety in ALK-addicted non-small cell lung cancer: A systematic revi... by Luca Mastrantoni, Giulia Giordano, Emanuele Vita, Guido Horn, Jacopo Russo, Armando Orlandi, Gennaro Daniele, Diana Giannarelli, Giampaolo Tortora, Emilio Bria

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Large Cell Neuro-Endocrine Carcinoma of the Lung: Current Treatment Options and Potential Future Opportunities by Miriam Grazia Ferrara, Miriam Grazia Ferrara, Alessio Stefani, Alessio Stefani, Michele Simbolo, Sara Pilotto, Maurizio Martini, Filippo Lococo, Emanuele Vita, Emanuele Vita, Marco Chiappetta, Alessandra Cancellieri, Ettore D’Argento, Ettore D’Argento, Rocco Trisolini, Guido Rindi, Aldo Scarpa, Stefano Margaritora, Michele Milella, Giampaolo Tortora, Giampaolo Tortora, Emilio Bria, Emilio Bria

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Prognostic Value of Beta-Tubulin-3 and c-Myc in Muscle Invasive Urothelial Carcinoma of the Bladder. by Francesco Massari, Emilio Bria, Chiara Ciccarese, Enrico Munari, Alessandra Modena, Valentina Zambonin, Isabella Sperduti, Walter Artibani, Liang Cheng, Guido Martignoni, Giampaolo Tortora, Matteo Brunelli

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Safety and Efficacy of a First-Line Chemotherapy Tailored by G8 Score in Elderly Metastatic or Locally Advanced Gastric and Gastro-Esophageal Cancer Patients: A Real-World Analysis by Ina Valeria Zurlo, Carmelo Pozzo, Antonia Strippoli, Samantha Mignogna, Michele Basso, Raffaella Vivolo, Giovanni Trovato, Michele Ciaburri, Franco Morelli, Emilio Bria, Silvana Leo, Giampaolo Tortora

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Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer by Carmine Carbone, Geny Piro, Vincenzo Di Noia, Ettore D’Argento, Emanuele Vita, Miriam Grazia Ferrara, Sara Pilotto, Michele Milella, Giovanni Cammarota, Antonio Gasbarrini, Giampaolo Tortora, Emilio Bria

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Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma,... by Luisa Carbognin, Sara Pilotto, Michele Milella, Vanja Vaccaro, Matteo Brunelli, Anna Caliò, Federica Cuppone, Isabella Sperduti, Diana Giannarelli, Marco Chilosi, Vincenzo Bronte, Aldo Scarpa, Emilio Bria, Giampaolo Tortora

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Cryoablation in Locoregional Management of Complex Unresectable Chest Neoplasms by Roberto Iezzi, Andrea Contegiacomo, Alessandro Posa, Nico Attempati, Ernesto Punzi, Alessandro Tanzilli, Stefano Margaritora, Maria Teresa Congedo, Alessandra Cassano, Emilio Bria, Luca Tagliaferri, Vincenzo Valentini, Cesare Colosimo, Riccardo Manfredi

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Tissue- and liquid-biopsy based NGS profiling in advanced non-small-cell lung cancer in a real-world setting: the IMMINENT study by Marco Sposito, Lorenzo Belluomini, Riccardo Nocini, Jessica Insolda, Ilaria Mariangela Scaglione, Jessica Menis, Michele Simbolo, Antonio Lugini, Federica Buzzacchino, Francesco Verderame, Francesca Spinnato, Giuseppe Aprile, Lorenzo Calvetti, Mario Occhipinti, Mario Occhipinti, Daniele Marinelli, Daniele Marinelli, Antonello Veccia, Fiorella Lombardo, Hector José Soto Parra, Francesco Ferraù, Clementina Savastano, Camilla Porta, Lorenzo Pradelli, Emilia Sicari, Silvia Castellani, Umberto Malapelle, Silvia Novello, Emilio Bria, Emilio Bria, Sara Pilotto, Michele Milella

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Intratumoral injection of TLR9 agonist promotes an immunopermissive microenvironment transition and causes cooperative antitumor activity in combination with anti-PD1 in pancreatic... by Paola Cappello, Maurizio Martini, Aldo Scarpa, Stefano Ugel, Francesco De Sanctis, Giampaolo Tortora, Emilio Bria, Vincenzo Corbo, Carmine Carbone, Geny Piro, Antonio Agostini, Pietro Delfino, Vincenzo Nasca, Francesco Spallotta, Claudio Sette

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Interleukin-8 in Colorectal Cancer: A Systematic Review and Meta-Analysis of Its Potential Role as a Prognostic Biomarker by Chiara Bazzichetto, Michele Milella, Ilaria Zampiva, Francesca Simionato, Carla Azzurra Amoreo, Simonetta Buglioni, Chiara Pacelli, Loredana Le Pera, Teresa Colombo, Emilio Bria, Massimo Zeuli, Donatella Del Bufalo, Isabella Sperduti, Fabiana Conciatori

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Adjuvant denosumab in early breast cancer: a systematic review and meta-analysis of randomized controlled clinical trials by Luca Mastrantoni, Giovanna Garufi, Elena Di Monte, Noemi Maliziola, Mariangela Pasqualoni, Letizia Pontolillo, Sergio Pannunzio, Maria Chiara Cannizzaro, Armando Di Bello, Alessandra Fabi, Antonella Palazzo, Giampaolo Tortora, Emilio Bria, Armando Orlandi

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