Editorial: Machine learning, epistasis, and protein engineering: From sequence-structure-function relationships to regulation of metabolic pathways Autor Frederic Cadet, Frederic Cadet, Emma Saavedra, Per-Olof Syren, Per-Olof Syren, Brigitte Gontero

Získat plný text

The contribution of two isozymes to the pyruvate kinase activity of Vibrio cholerae: One K+-dependent constitutively active and another K+-independent with essential allosteric act... Autor Carlos Guerrero-Mendiola, José J García-Trejo, Rusely Encalada, Emma Saavedra, Leticia Ramírez-Silva

Získat plný text

Repurposing the Antidiabetic Drugs Glyburide, Gliquidone, and Glipizide in Combination with Benznidazole for <i>Trypanosoma cruzi</i> Infection Autor Citlali Vázquez, Rusely Encalada, Isabel Jiménez-Galicia, Rogelio Gómez-Escobedo, Gildardo Rivera, Benjamín Nogueda-Torres, Emma Saavedra

Získat plný text

Identification of flux checkpoints in a metabolic pathway through white-box, grey-box and black-box modeling approaches Autor Ophélie Lo-Thong, Philippe Charton, Xavier F. Cadet, Brigitte Grondin-Perez, Emma Saavedra, Cédric Damour, Frédéric Cadet

Získat plný text

Inhibition of non flux-controlling enzymes deters cancer glycolysis by accumulation of regulatory metabolites of controlling steps Autor Álvaro Marín-Hernández, José Salud Rodríguez-Zavala, Isis Del Mazo-Monsalvo, Sara Rodríguez-Enríquez, Rafael Moreno-Sánchez, Emma Saavedra

Získat plný text

Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole Autor Edar O. Pech-Santiago, Raúl Argüello-García, Citlali Vázquez, Emma Saavedra, Iliana González-Hernández, Helgi Jung-Cook, Steven P. Rafferty, M. Guadalupe Ortega-Pierres

Získat plný text

Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole. Autor Edar O Pech-Santiago, Raúl Argüello-García, Citlali Vázquez, Emma Saavedra, Iliana González-Hernández, Helgi Jung-Cook, Steven P Rafferty, M Guadalupe Ortega-Pierres

Získat plný text

Air-adapted Methanosarcina acetivorans shows high methane production and develops resistance against oxygen stress. Autor Ricardo Jasso-Chávez, M Geovanni Santiago-Martínez, Elizabeth Lira-Silva, Erika Pineda, Armando Zepeda-Rodríguez, Javier Belmont-Díaz, Rusely Encalada, Emma Saavedra, Rafael Moreno-Sánchez

Získat plný text

Exploring Quinazoline Nitro-Derivatives as Potential Antichagasic Agents: Synthesis and In Vitro Evaluation Autor Citlali Vázquez, Audifás-Salvador Matus-Meza, Oswaldo Nuñez-Moreno, Brenda Michelle Barbosa-Sánchez, Victor Manuel Farías-Gutiérrez, Mariana Mendoza-Conde, Francisco Hernández-Luis, Emma Saavedra

Získat plný text

Molecular Docking-Based Virtual Screening of FDA-Approved Drugs Using Trypanothione Reductase Identified New Trypanocidal Agents Autor Rogelio Gómez-Escobedo, Domingo Méndez-Álvarez, Citlali Vázquez, Emma Saavedra, Karina Vázquez, Verónica Alcántara-Farfán, Joaquín Cordero-Martínez, Alonzo Gonzalez-Gonzalez, Gildardo Rivera, Benjamín Nogueda-Torres

Získat plný text

Physiological Role of Glutamate Dehydrogenase in Cancer Cells Autor Rafael Moreno-Sánchez, Álvaro Marín-Hernández, Juan C. Gallardo-Pérez, Silvia C. Pacheco-Velázquez, Diana X. Robledo-Cadena, Joaquín Alberto Padilla-Flores, Emma Saavedra, Sara Rodríguez-Enríquez

Získat plný text

Endoplasmic reticulum stress-sensing mechanism is activated in Entamoeba histolytica upon treatment with nitric oxide. Autor Julien Santi-Rocca, Sherri Smith, Christian Weber, Erika Pineda, Chung-Chau Hon, Emma Saavedra, Alfonso Olivos-García, Sandrine Rousseau, Marie-Agnès Dillies, Jean-Yves Coppée, Nancy Guillén

Získat plný text

Advances in Protozoan Epigenetic Targets and Their Inhibitors for the Development of New Potential Drugs Autor Carlos Gaona-López, Lenci K. Vazquez-Jimenez, Alonzo Gonzalez-Gonzalez, Timoteo Delgado-Maldonado, Eyrá Ortiz-Pérez, Benjamín Nogueda-Torres, Adriana Moreno-Rodríguez, Karina Vázquez, Emma Saavedra, Gildardo Rivera

Získat plný text

New Amino Naphthoquinone Derivatives as Anti-<i>Trypanosoma cruzi</i> Agents Targeting Trypanothione Reductase Autor Christian Espinosa-Bustos, Mariana Ortiz Pérez, Alonzo Gonzalez-Gonzalez, Ana María Zarate, Gildardo Rivera, Javier A. Belmont-Díaz, Emma Saavedra, Mauricio A. Cuellar, Karina Vázquez, Cristian O. Salas

Získat plný text

Non-linearity of Metabolic Pathways Critically Influences the Choice of Machine Learning Model Autor Ophélie Lo-Thong-Viramoutou, Ophélie Lo-Thong-Viramoutou, Ophélie Lo-Thong-Viramoutou, Philippe Charton, Philippe Charton, Philippe Charton, Xavier F. Cadet, Brigitte Grondin-Perez, Emma Saavedra, Cédric Damour, Frédéric Cadet, Frédéric Cadet, Frédéric Cadet

Získat plný text

Transcriptional Regulation of Energy Metabolism in Cancer Cells Autor Sara Rodríguez-Enríquez, Álvaro Marín-Hernández, Juan Carlos Gallardo-Pérez, Silvia Cecilia Pacheco-Velázquez, Javier Alejandro Belmont-Díaz, Diana Xochiquetzal Robledo-Cadena, Jorge Luis Vargas-Navarro, Norma Angélica Corona de la Peña, Emma Saavedra, Rafael Moreno-Sánchez

Získat plný text

Cultivation of gastrointestinal microbiota in a new growth system revealed dysbiosis and metabolic disruptions in carcinoma-bearing rats Autor Betsy Anaid Peña-Ocaña, Yuki Hoshiko, Mayel Silva-Flores, Toshinari Maeda, Israel Pérez-Torres, Rodolfo García-Contreras, Wilbert Gutiérrez-Sarmiento, Luz Hernández-Esquivel, Álvaro Marín-Hernández, Rosina Sánchez-Thomas, Emma Saavedra, José Salud Rodríguez-Zavala, Ricardo Jasso-Chávez

Získat plný text

Acetate Promotes a Differential Energy Metabolic Response in Human HCT 116 and COLO 205 Colon Cancer Cells Impacting Cancer Cell Growth and Invasiveness Autor Sara Rodríguez-Enríquez, Diana Xochiquetzal Robledo-Cadena, Juan Carlos Gallardo-Pérez, Silvia Cecilia Pacheco-Velázquez, Citlali Vázquez, Emma Saavedra, Jorge Luis Vargas-Navarro, Betsy Alejandra Blanco-Carpintero, Álvaro Marín-Hernández, Ricardo Jasso-Chávez, Rusely Encalada, Luz Ruiz-Godoy, José Luis Aguilar-Ponce, Rafael Moreno-Sánchez

Získat plný text