Is HER2-Low a New Clinical Entity or Merely a Biomarker for an Antibody Drug Conjugate? by Heidi Ko, Rebecca A. Previs, Kyle C. Strickland, Jonathan Klein, Brian Caveney, Chiara Chiruzzi, Marcia Eisenberg, Eric A. Severson, Shakti Ramkissoon, Kamal S. Saini

Get full text

Genomic landscape of non‐small‐cell lung cancer with methylthioadenosine phosphorylase (MTAP) deficiency by Prashanth Ashok Kumar, Stephen L. Graziano, Natalie Danziger, Dean Pavlick, Eric A. Severson, Shakti H. Ramkissoon, Richard S. P. Huang, Brennan Decker, Jeffrey S. Ross

Get full text

1455 Characterization of gene expression signatures of tumor immunogenicity and cellular proliferation from murine cancer models grown in vitro and in vivo by Marcia Eisenberg, Shakti Ramkissoon, Mary K Nesline, Kyle C Strickland, Zachary D Wallen, Taylor J Jensen, Brian Caveney, Prasanth Reddy, Eric A Severson, Sheri Barnes, Scott C Wise

Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and novel associa... by Zachary D. Wallen, Mary K. Nesline, Marni Tierno, Alison Roos, Erica Schnettler, Hatim Husain, Pratheesh Sathyan, Brian Caveney, Marcia Eisenberg, Eric A. Severson, Shakti H. Ramkissoon, Shakti H. Ramkissoon

Get full text

Mechanisms of immune modulation in the tumor microenvironment and implications for targeted therapy by Paulina Czajka-Francuz, Maria J. Prendes, Arun Mankan, Ángela Quintana, Sarabjot Pabla, Shakti Ramkissoon, Taylor J. Jensen, Sandra Peiró, Eric A. Severson, Bhagelu R. Achyut, Laura Vidal, Martine Poelman, Kamal S. Saini, Kamal S. Saini

Get full text

1499 Molecular and immune profiling of lobular-enriched versus non-lobular invasive breast cancers by Sarabjot Pabla, Marcia Eisenberg, Shengle Zhang, Shakti Ramkissoon, Kamal S Saini, Mary K Nesline, Jeffrey M Conroy, Kyle C Strickland, Heidi Ko, Rebecca A Previs, Zachary D Wallen, Jennifer B Jackson, Taylor J Jensen, Brian Caveney, Prasanth Reddy, Eric A Severson

From tissue-specific to tissue-agnostic: HER2 overexpression and the rise of antibody-drug conjugates by Heidi C. Ko, Kyle C. Strickland, Kyle C. Strickland, Dana Jaggessarsingh, Alicia Dillard, Michelle Green, Erin Newburn, Tiffany Sellaro, Jonathan L. Klein, Brian Caveney, Marcia Eisenberg, Eric A. Severson, Shakti Ramkissoon, Shakti Ramkissoon, Rebecca A. Previs, Rebecca A. Previs, Anis Toumeh

Get full text

513 Comprehensive genomic and immune profiling of ALK fusion-positive and negative lung adenocarcinomas by Sarabjot Pabla, Marcia Eisenberg, Shengle Zhang, Shakti Ramkissoon, Kamal S Saini, Mary K Nesline, Jeffrey M Conroy, Kyle C Strickland, Heidi Ko, Rebecca A Previs, Zachary D Wallen, Taylor J Jensen, Brian Caveney, Prasanth Reddy, Eric A Severson, Pratheesh Sathyan, Marc AT Muskavitch, Ken Culver

176 Immune microenvironment of primary versus metastatic melanoma of the brain by Sarabjot Pabla, Marcia Eisenberg, Erik Van Roey, Shuang Gao, Shengle Zhang, Shakti Ramkissoon, Mary K Nesline, Maria-Fernanda Senosain, Jeffrey M Conroy, Kyle C Strickland, Heidi Ko, Rebecca A Previs, Taylor J Jensen, Brian Caveney, Eric A Severson, Stephanie B Hastings, Robert Seager

183 Comprehensive genomic and immune profiling (CGIP) reveals a distinct genomic and immune gene expression profile for younger patients with non-small cell lung cancer (NSCLC) by Sarabjot Pabla, Shengle Zhang, Shakti Ramkissoon, Kamal S Saini, Mary K Nesline, Jeffrey M Conroy, Kyle C Strickland, Heidi Ko, Rebecca A Previs, Zachary D Wallen, Jennifer B Jackson, Taylor J Jensen, Brian Caveney, Prasanth Reddy, Eric A Severson, Stephanie B Hastings, Pratheesh Sathyan

175 Metastatic triple negative breast cancer has distinct tumor immune landscape by Sarabjot Pabla, Marcia Eisenberg, Shipra Gandhi, Erik Van Roey, Shuang Gao, Shengle Zhang, Shakti Ramkissoon, Mary K Nesline, Maria-Fernanda Senosain, Jeffrey M Conroy, Kyle C Strickland, Heidi Ko, Rebecca A Previs, Taylor J Jensen, Brian Caveney, Eric A Severson, Stephanie B Hastings, Robert Seager

The Impact of Prior Single-Gene Testing on Comprehensive Genomic Profiling Results for Patients with Non-Small Cell Lung Cancer by Mary K. Nesline, Vivek Subbiah, Rebecca A. Previs, Kyle C. Strickland, Heidi Ko, Paul DePietro, Michael D. Biorn, Maureen Cooper, Nini Wu, Jeffrey Conroy, Sarabjot Pabla, Shengle Zhang, Zachary D. Wallen, Pratheesh Sathyan, Kamal Saini, Marcia Eisenberg, Brian Caveney, Eric A. Severson, Shakti Ramkissoon

Get full text

184 Distinct immunotherapy immune response phenotypes in non-small cell lung cancer present with unique genomic alteration profiles by Sarabjot Pabla, Marcia Eisenberg, RJ Seager, Erik Van Roey, Shuang Gao, Shengle Zhang, Shakti Ramkissoon, Mary K Nesline, Maria-Fernanda Senosain, Jeffrey M Conroy, Kyle C Strickland, Rebecca A Previs, Zachary D Wallen, Taylor J Jensen, Brian Caveney, Prasanth Reddy, Eric A Severson, Stephanie B Hastings

Cancer testis antigen burden (CTAB): a novel biomarker of tumor-associated antigens in lung cancer by R. J. Seager, Maria-Fernanda Senosain, Erik Van Roey, Shuang Gao, Paul DePietro, Mary K. Nesline, Durga Prasad Dash, Shengle Zhang, Heidi Ko, Stephanie B. Hastings, Kyle C. Strickland, Rebecca A. Previs, Taylor J. Jensen, Marcia Eisenberg, Brian J. Caveney, Eric A. Severson, Shakti Ramkissoon, Jeffrey M. Conroy, Sarabjot Pabla

Get full text

Real-world comprehensive genomic and immune profiling reveals distinct age- and sex-based genomic and immune landscapes in tumors of patients with non-small cell lung cancer by Zachary D. Wallen, Heidi Ko, Mary K. Nesline, Stephanie B. Hastings, Kyle C. Strickland, Kyle C. Strickland, Rebecca A. Previs, Rebecca A. Previs, Shengle Zhang, Sarabjot Pabla, Jeffrey Conroy, Jennifer B. Jackson, Kamal S. Saini, Taylor J. Jensen, Marcia Eisenberg, Brian Caveney, Pratheesh Sathyan, Eric A. Severson, Shakti H. Ramkissoon, Shakti H. Ramkissoon

Get full text

Case report: Single gene testing and comprehensive genomic profiling in non-small cell lung cancer—a case series of divergent results from a large reference laboratory by Kyle C. Strickland, Kyle C. Strickland, Mary K. Nesline, Rebecca A. Previs, Rebecca A. Previs, Heidi Ko, Maureen Cooper, Jennifer R. Rushton, Zachary D. Wallen, Sarabjot Pabla, Jeffrey M. Conroy, Mark Sausen, Kamal S. Saini, Kamal S. Saini, Luca Cantini, Taylor J. Jensen, Brian J. Caveney, Marcia Eisenberg, Eric A. Severson, Shakti Ramkissoon, Shakti Ramkissoon

Get full text

Primary Adult Retroperitoneal Sarcoma: A Comprehensive Genomic Profiling Study by Andrea Necchi, Giuseppe Basile, Filippo Pederzoli, Marco Bandini, Petros Grivas, Gennady Bratslavsky, Philippe E. Spiess, J. Keith Killian, Douglas I. Lin, Erik Williams, Shakti Ramkissoon, Eric A. Severson, Brian M. Alexander, Jeffrey Venstrom, Prasanth Reddy, Kimberley McGregor, Julia A. Elvin, Alexa B. Schrock, Dean V. Pavlick, Dexter X. Jin, Sally E. Trabucco, Natalie Danzinger, Jeffrey S. Ross

Get full text