TLRs in COVID-19: How they drive immunopathology and the rationale for modulation by F. Linzee Mabrey, Eric D Morrell, Mark M Wurfel

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Mediators of monocyte chemotaxis and matrix remodeling are associated with mortality and pulmonary fibroproliferation in patients with severe COVID-19. by Sarah E Holton, Mallorie Mitchem, Hamid Chalian, Sudhakar Pipavath, Eric D Morrell, Pavan K Bhatraju, Jessica A Hamerman, Cate Speake, Uma Malhotra, Mark M Wurfel, Steven E Ziegler, Carmen Mikacenic

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Evaluating construct validity of computable acute respiratory distress syndrome definitions in adults hospitalized with COVID-19: an electronic health records based approach by Neha A. Sathe, Su Xian, F. Linzee Mabrey, David R. Crosslin, Sean D. Mooney, Eric D. Morrell, Kevin Lybarger, Meliha Yetisgen, Gail P. Jarvik, Pavan K. Bhatraju, Mark M. Wurfel

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Mitochondrial N-formyl methionine peptides contribute to exaggerated neutrophil activation in patients with COVID-19 by Runa Kuley, Bhargavi Duvvuri, Jeffrey J. Wallin, Nam Bui, Mary Vic Adona, Nicholas G. O’Connor, Sharon K. Sahi, Ian B. Stanaway, Mark M. Wurfel, Eric D. Morrell, W. Conrad Liles, Pavan K. Bhatraju, Christian Lood

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Presence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus-2 on Admission Is Associated With Decreased Mortality in COVID-19 Critical Illness by F. Linzee Mabrey, MD, Leila R. Zelnick, PhD, Eric D. Morrell, MD, Nicholas G. O’Connor, BS, Andrew Hart, BA, Mark M. Wurfel, MD, PhD, W. Conrad Liles, MD, PhD, Pavan K. Bhatraju, MD, MSc

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The transcriptional and phenotypic characteristics that define alveolar macrophage subsets in acute hypoxemic respiratory failure by Eric D. Morrell, Sarah E. Holton, Matthew Lawrance, Marika Orlov, Zoie Franklin, Mallorie A. Mitchem, Hannah DeBerg, Vivian H. Gersuk, Ashley Garay, Elizabeth Barnes, Ted Liu, Ithan D. Peltan, Angela Rogers, Steven Ziegler, Mark M. Wurfel, Carmen Mikacenic

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25-Hydroxycholesterol exacerbates vascular leak during acute lung injury by Jennifer H. Madenspacher, Eric D. Morrell, Jeffrey G. McDonald, Bonne M. Thompson, Yue Li, Konstantin G. Birukov, Anna A. Birukova, Renee D. Stapleton, Aidin Alejo, Peer W. Karmaus, Julie M. Meacham, Prashant Rai, Carmen Mikacenic, Mark M. Wurfel, Michael B. Fessler

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Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumo... by F. Linzee Mabrey, Hui Nian, Chang Yu, Elizabeth M. Barnes, Uma Malhotra, Carmen Mikacenic, Julia Goldstein, D. Shane O'Mahony, Julia Garcia-Diaz, Patricia Finn, Kirk Voelker, Eric D. Morrell, Wesley H. Self, Patrice M. Becker, Thomas R. Martin, Mark M. Wurfel

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Plasma Interleukin-6 Predicts Clinical Decline After Completion of Dexamethasone Therapy in Severe COVID-19 by F. Linzee Mabrey, MD, Pavan K. Bhatraju, MD, MSc, Eric D. Morrell, MD, Leila R. Zelnick, PhD, Neha A. Sathe, MD, Nicholas G. O’Connor, BS, Carmen Mikacenic, MD, Thomas R. Martin, MD, W. Conrad Liles, MD, PhD, Mark M. Wurfel, MD, PhD

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Biomarker Signatures of Severe Acute Kidney Injury in a Critically Ill Cohort of COVID-19 and Non-COVID-19 Acute Respiratory Illness by Neha A. Sathe, MD, MSc, Ana Mostaghim, MD, Elizabeth Barnes, BS, Nicholas G. O’Connor, BS, Sharon K. Sahi, MS, Sana S. Sakr, PhD, Jana M. Zahlan, BS, Craig H. Smith, MD, Michael Fitzpatrick, BS, Eric D. Morrell, MD, W. Conrad Liles, MD, PhD, Pavan K. Bhatraju, MD, MSc

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Proteomic Analyses in COVID-19-Associated Secondary Hemophagocytic Lymphohistiocytosis by Susan P. Canny, MD, PhD, Ian B. Stanaway, PhD, Sarah E. Holton, MD, PhD, Mallorie Mitchem, BA, Allison R. O’Rourke, PhD, Stephan Pribitzer, PhD, Sarah K. Baxter, MD, PhD, Mark M. Wurfel, MD, PhD, Uma Malhotra, MD, Jane H. Buckner, MD, Pavan K. Bhatraju, MD, Eric D. Morrell, MD, Cate Speake, PhD, Carmen Mikacenic, MD, Jessica A. Hamerman, PhD

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COVID-19 Across Pandemic Variant Periods: The Severe Acute Respiratory Infection-Preparedness (SARI-PREP) Study by Vikramjit Mukherjee, MD, FRCP, Radu Postelnicu, MD, Chelsie Parker, MS, Patrick S. Rivers, PhD, George L. Anesi, MD, MSCE, MBE, Adair Andrews, RN, MATD, Erin Ables, MA, Eric D. Morrell, MD, MA, David M. Brett-Major, MD, MPH, M. Jana Broadhurst, MD, PhD, J. Perren Cobb, MD, Amy Irwin, DNP, RN, Christopher J. Kratochvil, MD, Kelsey Krolikowski, BA, Vishakha K. Kumar, MD, MBA, Douglas P. Landsittel, PhD, Richard A. Lee, MD, Janice M. Liebler, MD, Leopoldo N. Segal, MD, Jonathan E. Sevransky, MD, MHS, Avantika Srivastava, MS, Timothy M. Uyeki, MD, MPH, Mark M. Wurfel, MD, PhD, David Wyles, MD, Laura E. Evans, MD, MSc, Karen Lutrick, PhD, Pavan K. Bhatraju, MD, MSc, on behalf of the Severe Acute Respiratory Infection-Preparedness (SARI-PREP) Study Group

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Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity by Pavan K. Bhatraju, MD, MSc, Eric D. Morrell, MD, Ian B. Stanaway, PhD, Neha A. Sathe, MD, MSc, Avantika Srivastava, MS, Radu Postelnicu, MD, Richard Green, BS, Adair Andrews, BSN, Martin Gonzalez, BS, Christopher J. Kratochvil, MD, Vishakha K. Kumar, BS, Tien-Ying Hsiang, PhD, Michael Gale, Jr, PhD, George L. Anesi, MD, David Wyles, MD, M. Jana Broadhurst, MD, PhD, David Brett-Major, MD, MPH, Vikramjit Mukherjee, MD, Jonathan E. Sevransky, MD, Douglas Landsittel, PhD, Chi Hung, MD, William A. Altemeier, MD, Sina A. Gharib, MD, Timothy M. Uyeki, MD, MPH, J. Perren Cobb, MD, Janice M. Liebler, MD, David R. Crosslin, PhD, Gail P. Jarvik, MD, Leopoldo N. Segal, MD, Laura Evans, MD, Carmen Mikacenic, MD, Mark M. Wurfel, MD, PhD

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