PD-L1 inhibitors in the pipeline: Promise and progress by Vito Vanella, Lucia Festino, Martina Strudel, Ester Simeone, Antonio M. Grimaldi, Paolo A. Ascierto

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Exosomal CD73 from serum of patients with melanoma suppresses lymphocyte functions and is associated with therapy resistance to anti-PD-1 agents by Mariaelena Capone, Gabriele Madonna, Ester Simeone, Paolo A Ascierto, Antonio Sorrentino, Roberta Turiello, Elva Morretta, Maria Chiara Monti, Rosa Azzaro, Silvana Morello, Pasquale Del Gaudio

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Baseline neutrophil-to-lymphocyte ratio (NLR) and derived NLR could predict overall survival in patients with advanced melanoma treated with nivolumab by Mariaelena Capone, Diana Giannarelli, Domenico Mallardo, Gabriele Madonna, Lucia Festino, Antonio Maria Grimaldi, Vito Vanella, Ester Simeone, Miriam Paone, Giuseppe Palmieri, Ernesta Cavalcanti, Corrado Caracò, Paolo Antonio Ascierto

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Electrochemotherapy efficacy evaluation for treatment of locally advanced stage III cutaneous squamous cell carcinoma: a 22-cases retrospective analysis by Gianluca Di Monta, Corrado Caracò, Ester Simeone, Antonio Maria Grimaldi, Ugo Marone, Massimiliano Di Marzo, Vito Vanella, Lucia Festino, Marco Palla, Stefano Mori, Nicola Mozzillo, Paolo Antonio Ascierto

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Immunotherapy Assessment: A New Paradigm for Radiologists by Vincenza Granata, Roberta Fusco, Sergio Venanzio Setola, Igino Simonetti, Carmine Picone, Ester Simeone, Lucia Festino, Vito Vanella, Maria Grazia Vitale, Agnese Montanino, Alessandro Morabito, Francesco Izzo, Paolo Antonio Ascierto, Antonella Petrillo

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Potential clinical implications of CD4+CD26high T cells for nivolumab treated melanoma patients by Domenico Galati, Serena Zanotta, Mariaelena Capone, Gabriele Madonna, Domenico Mallardo, Marilena Romanelli, Ester Simeone, Lucia Festino, Francesca Sparano, Rosa Azzaro, Rosaria De Filippi, Antonio Pinto, Chrystal M. Paulos, Paolo A. Ascierto

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308 Transcriptomic analysis of melanoma patients in adjuvant setting treated with anti PD1 therapy: real life study by Nicola Normanno, Andrew White, Mariaelena Capone, Gabriele Madonna, Corrado Caracò, Ester Simeone, Lucia Festino, Sarah Warren, Domenico Mallardo, Vito Vanella, Paolo Ascierto, Claudia Trojaniello, Maria Grazia Vitale, Antonio Sorrentino, Grazia D’Angelo, Marilena Tuffanelli

579 Evaluation of cemiplimab treatment duration: clinical outcomes in advanced CSCC by Francesca Sparano, Corrado Caracò, Ester Simeone, Assunta Esposito, Lucia Festino, Alfredo Budillon, Domenico Mallardo, Vito Vanella, Paolo Ascierto, Claudia Trojaniello, Maria Grazia Vitale, Margaret Ottaviano, Mario Mallardo, Eleonora Cioli, Teresa De Cristofaro, Boanca Arianna Facchini, Paolo Meinardi

41 CD39 affect the prognostic role of NLR via N2 neutrophils in metastatic melanoma patients treated with immunotherapy by Michael Bailey, Andrew White, Francesca Sparano, Alessandra Cesano, Corrado Caracò, Ester Simeone, Alfredo Budillon, Sarah Warren, SuFey Ong, Domenico Mallardo, Sarah Church, Ernesta Cavalcanti, Paolo Ascierto, Margaret Ottaviano, Paolo Chiodini, Piera Maiolino, Mario Fordellone, Bianca Arianna Facchini

CD39 and LDHA affects the prognostic role of NLR in metastatic melanoma patients treated with immunotherapy by Domenico Mallardo, Mario Fordellone, Andrew White, Margaret Ottaviano, Francesca Sparano, Michael Bailey, Arianna Bianca Facchini, Sufey Ong, Piera Maiolino, Corrado Caracò, Sarah Church, Ernesta Cavalcanti, Sarah Warren, Alfredo Budillon, Alessandra Cesano, Ester Simeone, Paolo Chiodini, Paolo Antonio Ascierto

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42 IL-6 as prognostic factor in adjuvant or metastatic skin cancer patients treated with immunotherapy – a deep biomarker analysis by Francesca Sparano, Corrado Caracò, Ester Simeone, Lucia Festino, Alfredo Budillon, Domenico Mallardo, Vito Vanella, Ernesta Cavalcanti, Paolo Ascierto, Claudia Trojaniello, Maria Grazia Vitale, Grazia D’Angelo, Marilena Tuffanelli, Sergio Arpino, Anita Minopoli, Mario Mallardo, Eleonora Cioli, Benedetta Alfano

Anorectal and Genital Mucosal Melanoma: Diagnostic Challenges, Current Knowledge and Therapeutic Opportunities of Rare Melanomas by Margaret Ottaviano, Emilio Francesco Giunta, Laura Marandino, Marianna Tortora, Laura Attademo, Davide Bosso, Cinzia Cardalesi, Antonietta Fabbrocini, Mario Rosanova, Antonia Silvestri, Liliana Montella, Pasquale Tammaro, Ester Marra, Claudia Trojaniello, Maria Grazia Vitale, Ester Simeone, Teresa Troiani, Bruno Daniele, Paolo Antonio Ascierto

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Ipilimumab and Stereotactic Radiosurgery with CyberKnife^® System in Melanoma Brain Metastases: A Retrospective Monoinstitutional Experience by Valentina Borzillo, Rossella Di Franco, Diana Giannarelli, Fabrizio Cammarota, Esmeralda Scipilliti, Emma D'Ippolito, Angela Petito, Marcello Serra, Sara Falivene, Antonio M. Grimaldi, Ester Simeone, Lucia Festino, Vito Vanella, Claudia Trojaniello, Maria Grazia Vitale, Gabriele Madonna, Paolo A. Ascierto, Paolo Muto

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A monocentric phase I study of vemurafenib plus cobimetinib plus PEG-interferon (VEMUPLINT) in advanced melanoma patients harboring the V600BRAF mutation by Ester Simeone, Giosuè Scognamiglio, Mariaelena Capone, Diana Giannarelli, Antonio M. Grimaldi, Domenico Mallardo, Gabriele Madonna, Marcello Curvietto, Assunta Esposito, Fabio Sandomenico, Francesco Sabbatino, Nicholas L. Bayless, Sarah Warren, SuFey Ong, Gerardo Botti, Keith T. Flaherty, Soldano Ferrone, Paolo A. Ascierto

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Clinical Categorization Algorithm (CLICAL) and Machine Learning Approach (SRF-CLICAL) to Predict Clinical Benefit to Immunotherapy in Metastatic Melanoma Patients: Real-World Evide... by Gabriele Madonna, Giuseppe V. Masucci, Mariaelena Capone, Domenico Mallardo, Antonio Maria Grimaldi, Ester Simeone, Vito Vanella, Lucia Festino, Marco Palla, Luigi Scarpato, Marilena Tuffanelli, Grazia D'angelo, Lisa Villabona, Isabelle Krakowski, Hanna Eriksson, Felipe Simao, Rolf Lewensohn, Paolo Antonio Ascierto

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BRAF Gene and Melanoma: Back to the Future by Margaret Ottaviano, Emilio Francesco Giunta, Marianna Tortora, Marcello Curvietto, Laura Attademo, Davide Bosso, Cinzia Cardalesi, Mario Rosanova, Pietro De Placido, Erica Pietroluongo, Vittorio Riccio, Brigitta Mucci, Sara Parola, Maria Grazia Vitale, Giovannella Palmieri, Bruno Daniele, Ester Simeone, on behalf of SCITO YOUTH

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1247 Gene signature predict autoimmune toxicity in patients with metastatic melanoma by Michael Bailey, Andrew White, Francesca Sparano, Alessandra Cesano, Corrado Caracò, Ester Simeone, Lucia Festino, Alfredo Budillon, Sarah Warren, Domenico Mallardo, Sarah Church, Vito Vanella, Ernesta Cavalcanti, Paolo Ascierto, Claudia Trojaniello, Maria Grazia Vitale, Margaret Ottaviano, Paolo Chiodini, Marilena Tuffanelli, Mario Fordellone, Bianca Arianna Facchini

IL-6 as new prognostic factor in patients with advanced cutaneous squamous cell carcinoma treated with cemiplimab by Domenico Mallardo, Ester Simeone, Lucia Festino, Marilena Tuffanelli, Vito Vanella, Claudia Trojaniello, Maria Grazia Vitale, Margaret Ottaviano, Mariaelena Capone, Gabriele Madonna, Francesca Sparano, Eleonora Cioli, Luigi Scarpato, Marco Palla, Rossella Di Trolio, Paolo Meinardi, Corrado Caracò, Gerardo Ferrara, Paolo Muto, Ernesta Cavalcanti, Paolo Antonio Ascierto

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The role of diabetes in metastatic melanoma patients treated with nivolumab plus relatlimab by Domenico Mallardo, Rachel Woodford, Alexander M. Menzies, Lisa Zimmer, Andrew williamson, Egle Ramelyte, Florentia Dimitriou, Alexandre Wicky, Roslyn Wallace, Mario Mallardo, Alessio Cortellini, Alfredo Budillon, Victoria Atkinson, Shahneen Sandhu, Michielin Olivier, Reinhard Dummer, Paul Lorigan, Dirk Schadendorf, Georgina V. Long, Ester Simeone, Paolo A. Ascierto

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24 Nivolumab serum concentration in metastatic melanoma patients could be related to anti-tumor activity gene and outcome by Diana Giannarelli, Nicola Normanno, Michael Bailey, Andrew White, Mariaelena Capone, Gabriele Madonna, Corrado Caracò, Ester Simeone, Assunta Esposito, Lucia Festino, Sarah Warren, Domenico Mallardo, Vito Vanella, Ernesta Cavalcanti, Paolo Ascierto, Claudia Trojaniello, Maria Grazia Vitale, Giusy Trillò, Maria Antonietta Isgrò, Grazia D’Angelo, Alessandro Manzoni, Piera Maiolino