Atypical Manifestation of X-linked Agammaglobulinemia – the Importance of Genetic Testing by Adam Markocsy, Daniela Kapustová, Andrej Čereš, Eva Froňková, Miloš Jeseňák

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P388: THERAPY OF ADULT PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA BASED ON PEDIATRIC-INSPIRED PROTOCOLS IN THE CZECH REPUBLIC IN 2007–2020 by Cyril Salek, Stepan Hrabovsky, František Folber, Jan Horacek, Zdenek Koristek, Tomáš Szotkowski, Pavla Pecherková, Eva Fronkova, Michael Doubek

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INFANT EXTRAMEDULLARY KMT2A REARRANGED T/MYELOID ACUTE LEUKEMIA MIMICKING LANGERHANS CELL HISTIOCYTOSIS by Barbora Vakrmanova, Ester Mejstrikova, Jakub Jonas, Petr Pavlicek, Marketa Zaliova, Marek Turnovec, Livia Molcanyova, Eva Fronkova, Ondrej Hrusak, Lucie Sramkova

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BIOLOGY OF BONE MARROW DISORDER CHARACTERIZE DISTINCT SUBTYPES OF REFRACTORY CYTOPENIA OF CHILDHOOD (RCC) by Martina Sukova, Ester Mejstrikova, Michaela Reiterova, Marketa Kubricanova-Zaliova, Eva Fronkova, Vit Campr, Zuzana Zemanova, Iveta Janotova, Lucie Sramkova, Jan Stary

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Acute lymphoblastic leukemia with aleukemic prodrome: preleukemic dynamics and possible mechanisms of immunosurveillance by Olga Zimmermannova, Marketa Zaliova, Anthony V. Moorman, Halima Al-Shehhi, Eva Fronkova, Zuzana Zemanova, Tomas Kalina, Ajay Vora, Jan Stary, Jan Trka, Ondrej Hrusak, Jan Zuna

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P397: IKZF1 ALTERATIONS HAVE A NEGATIVE IMPACT ON EARLY MOLECULAR RESPONSE AND SURVIVAL OF ADULT PATIENTS WITH B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA TREATED WITH GMALL 07/2... by Vaclava Polivkova, Stepan Hrabovsky, Zuzana Vrzalova, Jiri Stika, Jan Horacek, Pavla Pecherková, Hana Halamova, Jan Zuna, Jan Trka, Eva Fronkova, Marketa Zaliova, Michael Doubek, Katerina Machova Polakova, Cyril Salek

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Minimal residual disease in peripheral blood at day 15 identifies a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with superior prognosis by Jana Volejnikova, Ester Mejstrikova, Tatana Valova, Leona Reznickova, Ladislava Hodonska, Vladimir Mihal, Jaroslav Sterba, Yahia Jabali, Daniela Prochazkova, Bohumir Blazek, Jiri Hak, Zdenka Cerna, Ondrej Hrusak, Jan Stary, Jan Trka, Eva Fronkova

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<i>DUX4r</i>, <i>ZNF384r</i> and <i>PAX5</i>-P80R mutated B-cell precursor acute lymphoblastic leukemia frequently undergo monocytic switch by Michaela Novakova, Marketa Zaliova, Karel Fiser, Barbora Vakrmanova, Lucie Slamova, Alena Musilova, Monika Brüggemann, Matthias Ritgen, Eva Fronkova, Tomas Kalina, Jan Stary, Lucie Winkowska, Peter Svec, Alexandra Kolenova, Jan Stuchly, Jan Zuna, Jan Trka, Ondrej Hrusak, Ester Mejstrikova

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Blinatumomab in induction therapy improves molecular response in untreated adults with Ph- B-cell precursor acute lymphoblastic leukemia by Cyril Salek, Stepan Hrabovsky, Frantisek Folber, Zdenek Koristek, Jan M. Horacek, Eva Fronkova, Leona Rezkova Reznickova, Pavla Pecherkova, Petr Soukup, Barbora Dluhosova, Vaclava Polivkova, Jitka Krizkova, Katerina Machova Polakova, Zuzana Vrzalova, Hana Halamova, Jan Trka, Petr Cetkovsky, Michael Doubek

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Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria by Ester Mejstrikova, Jana Volejnikova, Eva Fronkova, Katerina Zdrahalova, Tomas Kalina, Jaroslav Sterba, Yahia Jabali, Vladimir Mihal, Bohumir Blazek, Zdena Cerna, Daniela Prochazkova, Jiri Hak, Zuzana Zemanova, Marie Jarosova, Alexandra Oltova, Petr Sedlacek, Jiri Schwarz, Jan Zuna, Jan Trka, Jan Stary, Ondrej Hrusak

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Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome by Michaela Nováková, Markéta Žaliová, Martina Suková, Marcin Wlodarski, Aleš Janda, Eva Froňková, Vít Campr, Kateřina Lejhancová, Ondřej Zapletal, Dagmar Pospíšilová, Zdeňka Černá, Tomáš Kuhn, Peter Švec, Vendula Pelková, Zuzana Zemanová, Gitte Kerndrup, Marry van den Heuvel-Eibrink, Vincent van der Velden, Charlotte Niemeyer, Tomáš Kalina, Jan Trka, Jan Starý, Ondřej Hrušák, Ester Mejstříková

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Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia? by Claire Schwab, Karin Nebral, Lucy Chilton, Cristina Leschi, Esmé Waanders, Judith M. Boer, Markéta Žaliová, Rosemary Sutton, Ingegerd Ivanov Öfverholm, Kentaro Ohki, Yuka Yamashita, Stefanie Groeneveld-Krentz, Eva Froňková, Marleen Bakkus, Joelle Tchinda, Thayana da Conceição Barbosa, Grazia Fazio, Wojciech Mlynarski, Agata Pastorczak, Giovanni Cazzaniga, Maria S. Pombo-de-Oliveira, Jan Trka, Renate Kirschner-Schwabe, Toshihiko Imamura, Gisela Barbany, Martin Stanulla, Andishe Attarbaschi, Renate Panzer-Grümayer, Roland P. Kuiper, Monique L. den Boer, Hélène Cavé, Anthony V. Moorman, Christine J. Harrison, Sabine Strehl

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